node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADRA1D | AVPR1A | ENSSTOP00000015085 | ENSSTOP00000015243 | Adrenoceptor alpha 1D. | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. | 0.468 |
ADRA1D | HRH2 | ENSSTOP00000015085 | ENSSTOP00000024884 | Adrenoceptor alpha 1D. | Histamine receptor H2; Belongs to the G-protein coupled receptor 1 family. | 0.435 |
ADRA1D | HTR2C | ENSSTOP00000015085 | ENSSTOP00000019818 | Adrenoceptor alpha 1D. | 5-hydroxytryptamine receptor 2C. | 0.422 |
ADRA1D | TBXA2R | ENSSTOP00000015085 | ENSSTOP00000020611 | Adrenoceptor alpha 1D. | Thromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. | 0.629 |
AKT1 | CAV1 | ENSSTOP00000028457 | ENSSTOP00000015394 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | 0.597 |
AKT1 | EGFR | ENSSTOP00000028457 | ENSSTOP00000006038 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Receptor protein-tyrosine kinase. | 0.528 |
AKT1 | PDE5A | ENSSTOP00000028457 | ENSSTOP00000021040 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Phosphodiesterase. | 0.486 |
AKT1 | SHC1 | ENSSTOP00000028457 | ENSSTOP00000000045 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | SHC adaptor protein 1. | 0.605 |
AVPR1A | ADRA1D | ENSSTOP00000015243 | ENSSTOP00000015085 | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. | Adrenoceptor alpha 1D. | 0.468 |
AVPR1A | AVPR1B | ENSSTOP00000015243 | ENSSTOP00000017393 | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.862 |
AVPR1A | AVPR2 | ENSSTOP00000015243 | ENSSTOP00000007473 | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.877 |
AVPR1A | OXTR | ENSSTOP00000015243 | ENSSTOP00000018112 | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. | Oxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.513 |
AVPR1B | AVPR1A | ENSSTOP00000017393 | ENSSTOP00000015243 | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. | 0.862 |
AVPR1B | AVPR2 | ENSSTOP00000017393 | ENSSTOP00000007473 | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.862 |
AVPR1B | OXTR | ENSSTOP00000017393 | ENSSTOP00000018112 | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Oxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.431 |
AVPR2 | AVPR1A | ENSSTOP00000007473 | ENSSTOP00000015243 | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. | 0.877 |
AVPR2 | AVPR1B | ENSSTOP00000007473 | ENSSTOP00000017393 | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.862 |
CAV1 | AKT1 | ENSSTOP00000015394 | ENSSTOP00000028457 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.597 |
CAV1 | EGFR | ENSSTOP00000015394 | ENSSTOP00000006038 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Receptor protein-tyrosine kinase. | 0.956 |
CAV1 | ICAM1 | ENSSTOP00000015394 | ENSSTOP00000026234 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Intercellular adhesion molecule 1. | 0.536 |