STRINGSTRING
CREB3L1 CREB3L1 PPARG PPARG I3MJJ6_ICTTR I3MJJ6_ICTTR DDX5 DDX5 AXIN1 AXIN1 SMAD5 SMAD5 MYOCD MYOCD SMAD1 SMAD1 COL1A2 COL1A2 SMAD3 SMAD3 DAB2 DAB2 COL3A1 COL3A1 USP15 USP15 SKI SKI PRDM16 PRDM16 LOC101960243 LOC101960243 ACVR1C ACVR1C MEN1 MEN1 ZEB2 ZEB2 ENSSTOP00000026660 ENSSTOP00000026660 ENSSTOP00000026381 ENSSTOP00000026381 TRIM33 TRIM33 SMURF2 SMURF2 LOC101955706 LOC101955706 DROSHA DROSHA MEF2A MEF2A Yy1 Yy1 TGFBR2 TGFBR2 EID2 EID2 Gata4 Gata4 Hmga2 Hmga2 JUN JUN RGCC RGCC ZBTB7A ZBTB7A FOXA2 FOXA2 RANBP3L RANBP3L AXIN2 AXIN2 SKOR2 SKOR2 BMP2 BMP2 SAV1 SAV1 SMAD4 SMAD4 TGFB1I1 TGFB1I1 Tob1 Tob1 SMAD9 SMAD9 SKIL SKIL CITED1 CITED1 CITED2 CITED2 FERMT2 FERMT2 TGFBRAP1 TGFBRAP1 ANKRD1 ANKRD1 FOXH1 FOXH1 PURA PURA LDLRAD4 LDLRAD4 ACVRL1 ACVRL1 ACVR1B ACVR1B SMAD6 SMAD6 USP9X USP9X RNF111 RNF111 PMEPA1 PMEPA1 MAGI2 MAGI2 SKOR1 SKOR1 FOS FOS PAX6 PAX6 SNW1 SNW1 SMAD2 SMAD2 ZC3H3 ZC3H3 INTS8 INTS8 ACVR1 ACVR1 CREBBP CREBBP FLNA FLNA RANBP3 RANBP3 SMAD7 SMAD7 TGFBR3 TGFBR3 STUB1 STUB1 TGIF1 TGIF1 CTNNB1 CTNNB1 PARP1 PARP1 BMPR1A BMPR1A ZMIZ1 ZMIZ1 COL5A2 COL5A2 SMURF1 SMURF1 BMPR1B BMPR1B PPM1A PPM1A PML PML TGFBR1 TGFBR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
I3MJJ6_ICTTRPeptidylprolyl isomerase. (98 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
AXIN1Axin 1. (869 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
MYOCDMyocardin. (894 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
DAB2DAB adaptor protein 2. (767 aa)
COL3A1Collagen type III alpha 1 chain. (1462 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
SKISKI proto-oncogene. (730 aa)
PRDM16PR/SET domain 16. (1127 aa)
LOC101960243Uncharacterized protein. (175 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
MEN1Menin 1. (616 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1249 aa)
ENSSTOP00000026660Uncharacterized protein. (178 aa)
ENSSTOP00000026381Uncharacterized protein. (87 aa)
TRIM33Tripartite motif containing 33. (1028 aa)
SMURF2E3 ubiquitin-protein ligase. (740 aa)
LOC101955706Peptidylprolyl isomerase. (108 aa)
DROSHADrosha ribonuclease III. (1019 aa)
MEF2AMyocyte enhancer factor 2A. (496 aa)
Yy1Uncharacterized protein. (190 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
EID2EP300 interacting inhibitor of differentiation 2. (242 aa)
Gata4GATA-type domain-containing protein. (212 aa)
Hmga2Uncharacterized protein. (109 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
RGCCRegulator of cell cycle. (161 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (414 aa)
FOXA2Forkhead box A2. (463 aa)
RANBP3LRAN binding protein 3 like. (490 aa)
AXIN2Axin 2. (840 aa)
SKOR2SKI family transcriptional corepressor 2. (837 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
SAV1Salvador family WW domain containing protein 1. (335 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (479 aa)
Tob1Uncharacterized protein. (345 aa)
SMAD9Mothers against decapentaplegic homolog. (452 aa)
SKILSKI like proto-oncogene. (677 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (195 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (274 aa)
FERMT2Fermitin family member 2. (680 aa)
TGFBRAP1Transforming growth factor beta receptor associated protein 1. (860 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
FOXH1Forkhead box H1. (370 aa)
PURAPurine rich element binding protein A. (266 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (306 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
SMAD6Mothers against decapentaplegic homolog. (496 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2554 aa)
RNF111Ring finger protein 111. (984 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (264 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1188 aa)
SKOR1SKI family transcriptional corepressor 1. (862 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
PAX6Paired box 6. (436 aa)
SNW1SNW domain containing 1. (554 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
ZC3H3Zinc finger CCCH-type containing 3. (958 aa)
INTS8Integrator complex subunit 8. (994 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
CREBBPCREB binding protein. (2410 aa)
FLNAFilamin A. (2647 aa)
RANBP3RAN binding protein 3. (429 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
TGFBR3Transforming growth factor beta receptor 3. (851 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
TGIF1TGFB induced factor homeobox 1. (272 aa)
CTNNB1Catenin beta 1. (781 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1068 aa)
COL5A2Collagen type V alpha 2 chain. (1117 aa)
SMURF1E3 ubiquitin-protein ligase. (753 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (382 aa)
PMLPromyelocytic leukemia. (877 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (489 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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