STRINGSTRING
GBA2 GBA2 ASAH2 ASAH2 Smpd5 Smpd5 NEU2 NEU2 ACER2 ACER2 SMPD4 SMPD4 GALC GALC CEL CEL NAGA NAGA GM2A GM2A GBA3 GBA3 SMPD2 SMPD2 ZPBP2 ZPBP2 Hexa Hexa NEU3 NEU3 TMEM130 TMEM130 SMPD1 SMPD1 GBA GBA PNLIPRP2 PNLIPRP2 HEXB HEXB ASAH1 ASAH1 GLA GLA SMPDL3B SMPDL3B MGST2 MGST2 ACER3 ACER3 SGPL1 SGPL1 ACER1 ACER1 ENPP2 ENPP2 CYP1B1 CYP1B1 NEU1 NEU1 LCT LCT SMPD3 SMPD3 ENPP7 ENPP7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (919 aa)
ASAH2Neutral ceramidase. (716 aa)
Smpd5Endo/exonuclease/phosphatase domain-containing protein. (472 aa)
NEU2Neuraminidase 2. (388 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
SMPD4Sphingomyelin phosphodiesterase 4. (827 aa)
GALCGalactosylceramidase. (622 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (558 aa)
NAGAAlpha-galactosidase. (423 aa)
GM2AGM2 ganglioside activator. (192 aa)
GBA3Glucosylceramidase beta 3 (gene/pseudogene); Belongs to the glycosyl hydrolase 1 family. (472 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (419 aa)
ZPBP2Zona pellucida binding protein 2. (337 aa)
HexaBeta-hexosaminidase. (527 aa)
NEU3Neuraminidase 3. (435 aa)
TMEM130Transmembrane protein 130. (338 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
GBAGlucosylceramidase. (516 aa)
PNLIPRP2Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (481 aa)
HEXBBeta-hexosaminidase. (538 aa)
ASAH1N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (395 aa)
GLAAlpha-galactosidase. (427 aa)
SMPDL3BAcid sphingomyelinase-like phosphodiesterase. (456 aa)
MGST2Microsomal glutathione S-transferase 2. (153 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (268 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (915 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
NEU1Neuraminidase 1. (416 aa)
LCTLactase. (1928 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
ENPP7Ectonucleotide pyrophosphatase/phosphodiesterase 7. (427 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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