STRINGSTRING
PAQR7 PAQR7 CTSV CTSV AGXT AGXT ENG ENG AIFM1 AIFM1 BAD BAD OR51E2 OR51E2 Hdac8 Hdac8 ALDH3A1 ALDH3A1 GABRB1 GABRB1 AREG AREG GNRH1 GNRH1 CPN1 CPN1 GBA GBA MAP2K1 MAP2K1 ESRRG ESRRG CLDN1 CLDN1 URI1 URI1 PLAT PLAT ZFP36L1 ZFP36L1 TGFB1 TGFB1 ERRFI1 ERRFI1 GLB1 GLB1 SCGB1A1 SCGB1A1 TFPI TFPI RXRG RXRG PCSK1 PCSK1 CYP7B1 CYP7B1 PPARA PPARA IGFBP2 IGFBP2 UCN UCN IGF1R IGF1R ADCYAP1 ADCYAP1 CDO1 CDO1 TAF7 TAF7 AGTR2 AGTR2 DDX5 DDX5 BMP7 BMP7 TNF TNF PIK3CA PIK3CA ABCA3 ABCA3 LOC101969101 LOC101969101 LOC101969382 LOC101969382 EPO EPO DDX17 DDX17 ABCA2 ABCA2 SLIT3 SLIT3 TXNIP TXNIP SOX30 SOX30 Tbl1x Tbl1x IL1RN IL1RN BCKDHB BCKDHB PCK1 PCK1 RBFOX2 RBFOX2 LOC101967926 LOC101967926 SST SST Aqp1 Aqp1 GHRHR GHRHR GHSR GHSR ZMIZ1 ZMIZ1 PARP1 PARP1 ADIPOQ ADIPOQ PFKFB1 PFKFB1 Ube2l3 Ube2l3 LOX LOX HSD11B2 HSD11B2 GOT1 GOT1 STC1 STC1 Rest Rest CALCOCO1 CALCOCO1 Eif4ebp1 Eif4ebp1 ESR1 ESR1 EGFR EGFR JAK2 JAK2 NPC1 NPC1 IL10 IL10 METTL21C METTL21C LOC101957447 LOC101957447 USP8 USP8 ABHD2 ABHD2 PADI2 PADI2 UBR5 UBR5 CRH CRH MAOB MAOB TRIM63 TRIM63 UCP3 UCP3 CST11 CST11 I3M4W8_ICTTR I3M4W8_ICTTR SCNN1G SCNN1G NR3C2 NR3C2 PDCD7 PDCD7 FOSL1 FOSL1 TAT TAT FLT3 FLT3 TSPO TSPO RBBP7 RBBP7 SAFB SAFB TPH2 TPH2 KDM3A KDM3A GPI GPI DAXX DAXX EIF4E EIF4E HMGCS2 HMGCS2 FBXO32 FBXO32 CYP1B1 CYP1B1 LOC101955676 LOC101955676 MSTN MSTN TGFB2 TGFB2 BCHE BCHE BMP4 BMP4 TYMS TYMS GSK3A GSK3A DDIT4 DDIT4 ALAD ALAD CCND1 CCND1 Hnrnpu Hnrnpu CPS1 CPS1 PCK2 PCK2 NR3C1 NR3C1 NEFL NEFL Sgk1 Sgk1 SSTR5 SSTR5 AVPR1A AVPR1A AR AR CAV1 CAV1 Acr Acr SSTR2 SSTR2 SLC12A3 SLC12A3 I3MU87_ICTTR I3MU87_ICTTR MDK MDK LCAT LCAT EPHX1 EPHX1 I3MVI7_ICTTR I3MVI7_ICTTR BCL2 BCL2 I3MVL6_ICTTR I3MVL6_ICTTR RXRA RXRA Ppp1r9b Ppp1r9b AGTR1 AGTR1 LOC101960216 LOC101960216 LOC101976546 LOC101976546 SOX10 SOX10 SPP1 SPP1 Fibin Fibin ZFP36L2 ZFP36L2 ZFP36 ZFP36 RWDD1 RWDD1 BMP6 BMP6 LOC101959454 LOC101959454 MED1 MED1 I3N090_ICTTR I3N090_ICTTR PTGER2 PTGER2 ACOD1 ACOD1 I3N0W3_ICTTR I3N0W3_ICTTR OXTR OXTR SMYD3 SMYD3 ACTA1 ACTA1 RXRB RXRB LOC101960206 LOC101960206 PGR PGR GDNF GDNF YWHAH YWHAH I3N5X0_ICTTR I3N5X0_ICTTR NPAS4 NPAS4 LOC101968529 LOC101968529 AXIN2 AXIN2 GJB2 GJB2 LOC101968765 LOC101968765 I3N7W8_ICTTR I3N7W8_ICTTR LOC101967640 LOC101967640 Rps6kb1 Rps6kb1 ESRRA ESRRA SSTR4 SSTR4 PHB2 PHB2 ANXA1 ANXA1 NCOA2 NCOA2 POU4F2 POU4F2 ANXA3 ANXA3 SERPINF1 SERPINF1 ADAM9 ADAM9 BPIFB2 BPIFB2 MGARP MGARP SSTR3 SSTR3 TFAP4 TFAP4 JUN JUN I3NC46_ICTTR I3NC46_ICTTR Foxo3 Foxo3 ESRRB ESRRB TRH TRH I3NCK5_ICTTR I3NCK5_ICTTR TLR2 TLR2 Phb Phb SRD5A2 SRD5A2 TGFB3 TGFB3 TH TH Pcna Pcna ALPL ALPL CYBB CYBB PAQR8 PAQR8 FOSB FOSB MYOD1 MYOD1 GSK3B GSK3B LOC101968945 LOC101968945 TMF1 TMF1 FKBP4 FKBP4 ADTRP ADTRP MT-ND3 MT-ND3 LOC101963381 LOC101963381 PAM PAM CYBA CYBA LOC101962631 LOC101962631 TGFBR2 TGFBR2 ENSSTOP00000024982 ENSSTOP00000024982 PTGES3 PTGES3 KCNMA1 KCNMA1 PTPRU PTPRU ATP1A2 ATP1A2 CFLAR CFLAR TRIP4 TRIP4 FAM107A FAM107A NEDD4 NEDD4 NKX3-1 NKX3-1 COL1A1 COL1A1 PIK3R1 PIK3R1 ENSSTOP00000026272 ENSSTOP00000026272 ENSSTOP00000026381 ENSSTOP00000026381 CARM1 CARM1 ADM ADM Arid1a Arid1a ASS1 ASS1 PIAS2 PIAS2 NR1H3 NR1H3 Slco1b3 Slco1b3 ENSSTOP00000028389 ENSSTOP00000028389 GPR83 GPR83 PAPPA PAPPA NTRK3 NTRK3 Wbp2 Wbp2 ACSBG1 ACSBG1 SREBF1 SREBF1 LOC101959938 LOC101959938 ATP5F1A ATP5F1A ESR2 ESR2 IGF1 IGF1 PPARGC1B PPARGC1B DAB2 DAB2 ATP1A1 ATP1A1 SCNN1B SCNN1B NCOA1 NCOA1 UBE3A UBE3A ATP2B1 ATP2B1 IDH1 IDH1 TRERF1 TRERF1 GPER1 GPER1 CNGA3 CNGA3 SLIT2 SLIT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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PAQR7Progestin and adipoQ receptor family member 7. (345 aa)
CTSVCathepsin V; Belongs to the peptidase C1 family. (332 aa)
AGXTSerine--pyruvate aminotransferase. (414 aa)
ENGEndoglin. (463 aa)
AIFM1Apoptosis inducing factor mitochondria associated 1. (613 aa)
BADBCL2 associated agonist of cell death. (208 aa)
OR51E2Olfactory receptor. (320 aa)
Hdac8Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (377 aa)
ALDH3A1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (453 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
AREGAmphiregulin. (252 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (92 aa)
CPN1Carboxypeptidase N subunit 1. (459 aa)
GBAGlucosylceramidase. (516 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
ESRRGEstrogen related receptor gamma. (458 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
URI1URI1 prefoldin like chaperone. (456 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (560 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (459 aa)
GLB1Beta-galactosidase. (668 aa)
SCGB1A1Secretoglobin family 1A member 1. (93 aa)
TFPITissue factor pathway inhibitor. (301 aa)
RXRGRetinoid X receptor gamma. (463 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (753 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (497 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
IGFBP2Insulin like growth factor binding protein 2. (308 aa)
UCNUrocortin. (127 aa)
IGF1RTyrosine-protein kinase receptor. (1368 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
CDO1Cysteine dioxygenase. (200 aa)
TAF7TATA-box binding protein associated factor 7. (349 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (361 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ABCA3ATP binding cassette subfamily A member 3. (1704 aa)
LOC101969101Sulfotransferase; Belongs to the sulfotransferase 1 family. (295 aa)
LOC101969382Sulfotransferase; Belongs to the sulfotransferase 1 family. (295 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (729 aa)
ABCA2ATP binding cassette subfamily A member 2. (2414 aa)
SLIT3Slit guidance ligand 3. (1385 aa)
TXNIPThioredoxin interacting protein. (391 aa)
SOX30SRY-box transcription factor 30. (774 aa)
Tbl1xUncharacterized protein. (530 aa)
IL1RNInterleukin-1. (177 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (326 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
RBFOX2RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events. (378 aa)
LOC101967926Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (124 aa)
SSTSomatostatin. (116 aa)
Aqp1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1068 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (471 aa)
Ube2l3UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
LOXLysyl oxidase. (397 aa)
HSD11B2Hydroxysteroid 11-beta dehydrogenase 2. (398 aa)
GOT1Aspartate aminotransferase. (413 aa)
STC1Stanniocalcin 1. (247 aa)
RestUncharacterized protein. (328 aa)
CALCOCO1Calcium binding and coiled-coil domain 1. (691 aa)
Eif4ebp1Uncharacterized protein. (118 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (593 aa)
EGFRReceptor protein-tyrosine kinase. (1192 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
NPC1NPC intracellular cholesterol transporter 1. (1277 aa)
IL10Interleukin 10. (178 aa)
METTL21CMethyltransferase like 21C. (263 aa)
LOC101957447Uncharacterized protein. (93 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1097 aa)
ABHD2Abhydrolase domain containing 2. (425 aa)
PADI2Peptidyl arginine deiminase 2. (674 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2782 aa)
CRHCorticotropin releasing hormone. (180 aa)
MAOBAmine oxidase. (520 aa)
TRIM63Tripartite motif containing 63. (354 aa)
UCP3Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (308 aa)
CST11Cystatin 11. (137 aa)
I3M4W8_ICTTRUncharacterized protein. (207 aa)
SCNN1GSodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (649 aa)
NR3C2Nuclear receptor subfamily 3 group C member 2. (985 aa)
PDCD7Programmed cell death 7. (259 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (275 aa)
TATTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (454 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (985 aa)
TSPOTranslocator protein. (169 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (425 aa)
SAFBScaffold attachment factor B. (866 aa)
TPH2Tryptophan hydroxylase 2. (491 aa)
KDM3ALysine demethylase 3A. (1320 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)
DAXXDeath domain associated protein. (740 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (218 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (507 aa)
FBXO32F-box protein 32. (355 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
LOC101955676RING-type domain-containing protein. (326 aa)
MSTNMyostatin. (376 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
BCHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (579 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
TYMSUncharacterized protein. (218 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (395 aa)
DDIT4DNA damage inducible transcript 4. (228 aa)
ALADDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (329 aa)
CCND1Cyclin D1. (250 aa)
HnrnpuB30.2/SPRY domain-containing protein. (411 aa)
CPS1Carbamoyl-phosphate synthase 1. (1500 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
NR3C1Nuclear receptor subfamily 3 group C member 1. (778 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (509 aa)
Sgk1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (454 aa)
SSTR5Somatostatin receptor 5; Belongs to the G-protein coupled receptor 1 family. (363 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. (418 aa)
ARAndrogen receptor. (884 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
AcrPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (271 aa)
SSTR2Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
SLC12A3Solute carrier family 12 member 3. (1004 aa)
I3MU87_ICTTRProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (250 aa)
MDKMidkine. (143 aa)
LCATLecithin-cholesterol acyltransferase. (440 aa)
EPHX1Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. (454 aa)
I3MVI7_ICTTRSulfotransferase; Belongs to the sulfotransferase 1 family. (352 aa)
BCL2BCL2 apoptosis regulator. (195 aa)
I3MVL6_ICTTRUncharacterized protein. (192 aa)
RXRARetinoid X receptor alpha. (461 aa)
Ppp1r9bPDZ domain-containing protein. (361 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (360 aa)
LOC1019602163Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (373 aa)
LOC101976546PKS_ER domain-containing protein. (375 aa)
SOX10SRY-box transcription factor 10. (466 aa)
SPP1Secreted phosphoprotein 1. (309 aa)
FibinUncharacterized protein. (211 aa)
ZFP36L2ZFP36 ring finger protein like 2. (489 aa)
ZFP36ZFP36 ring finger protein. (324 aa)
RWDD1RWD domain containing 1. (199 aa)
BMP6Bone morphogenetic protein 6. (507 aa)
LOC1019594543Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (373 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1575 aa)
I3N090_ICTTRUncharacterized protein. (207 aa)
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (361 aa)
ACOD1Aconitate decarboxylase 1. (473 aa)
I3N0W3_ICTTRBAF250_C domain-containing protein. (135 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (391 aa)
SMYD3SET and MYND domain containing 3. (428 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
RXRBRetinoid X receptor beta. (531 aa)
LOC101960206Uncharacterized protein. (207 aa)
PGRProgesterone receptor. (932 aa)
GDNFGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (212 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
I3N5X0_ICTTRUncharacterized protein. (183 aa)
NPAS4Neuronal PAS domain protein 4. (802 aa)
LOC101968529Sulfotransferase; Belongs to the sulfotransferase 1 family. (265 aa)
AXIN2Axin 2. (840 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa)
LOC101968765Uncharacterized protein. (187 aa)
I3N7W8_ICTTRUncharacterized protein; Belongs to the TCP-1 chaperonin family. (202 aa)
LOC101967640Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (125 aa)
Rps6kb1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
ESRRAEstrogen related receptor alpha. (422 aa)
SSTR4Somatostatin receptor 4; Belongs to the G-protein coupled receptor 1 family. (387 aa)
PHB2Prohibitin. (299 aa)
ANXA1Annexin. (346 aa)
NCOA2Nuclear receptor coactivator. (1465 aa)
POU4F2POU domain protein. (410 aa)
ANXA3Annexin. (323 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (417 aa)
ADAM9ADAM metallopeptidase domain 9. (782 aa)
BPIFB2BPI fold containing family B member 2. (458 aa)
MGARPMitochondria localized glutamic acid rich protein. (236 aa)
SSTR3Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (428 aa)
TFAP4Transcription factor AP-4. (338 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
I3NC46_ICTTRNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (397 aa)
Foxo3Forkhead box O3. (673 aa)
ESRRBEstrogen related receptor beta. (454 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (240 aa)
I3NCK5_ICTTRCARD domain-containing protein. (102 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (784 aa)
PhbProhibitin. (272 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (246 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
THTyrosine hydroxylase. (497 aa)
PcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
ALPLAlkaline phosphatase. (524 aa)
CYBBCytochrome b-245 beta chain. (549 aa)
PAQR8Progestin and adipoQ receptor family member 8. (354 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (317 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
LOC101968945Uncharacterized protein; Belongs to the peptidase C1 family. (339 aa)
TMF1TATA element modulatory factor 1. (1090 aa)
FKBP4Peptidylprolyl isomerase. (459 aa)
ADTRPAndrogen dependent TFPI regulating protein. (219 aa)
MT-ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (115 aa)
LOC101963381Prohibitin. (297 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (979 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (195 aa)
LOC101962631Prohibitin. (247 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
ENSSTOP00000024982GRAM domain-containing protein. (244 aa)
PTGES3CS domain-containing protein. (182 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1219 aa)
PTPRUProtein tyrosine phosphatase receptor type U. (1444 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (488 aa)
TRIP4Thyroid hormone receptor interactor 4. (581 aa)
FAM107AFamily with sequence similarity 107 member A. (144 aa)
NEDD4E3 ubiquitin-protein ligase. (901 aa)
NKX3-1NK3 homeobox 1. (144 aa)
COL1A1Collagen type I alpha 1 chain. (1268 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSSTOP00000026272CS domain-containing protein. (150 aa)
ENSSTOP00000026381Uncharacterized protein. (87 aa)
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (598 aa)
ADMAdrenomedullin. (188 aa)
Arid1aARID domain-containing protein. (1014 aa)
ASS1Argininosuccinate synthase 1. (412 aa)
PIAS2Protein inhibitor of activated STAT 2. (615 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (444 aa)
Slco1b3Solute carrier organic anion transporter family member. (687 aa)
ENSSTOP00000028389Uncharacterized protein. (113 aa)
GPR83G protein-coupled receptor 83; Belongs to the G-protein coupled receptor 1 family. (424 aa)
PAPPAPappalysin 1. (1549 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
Wbp2GRAM domain-containing protein. (261 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (730 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1152 aa)
LOC1019599383Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (373 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa)
ESR2Estrogen receptor 2. (525 aa)
IGF1Insulin like growth factor 1. (166 aa)
PPARGC1BPPARG coactivator 1 beta. (1033 aa)
DAB2DAB adaptor protein 2. (767 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (640 aa)
NCOA1Nuclear receptor coactivator. (1442 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (874 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (413 aa)
TRERF1Transcriptional regulating factor 1. (1213 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (688 aa)
SLIT2Slit guidance ligand 2. (1559 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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