STRINGSTRING
NIPBL NIPBL TCF7L2 TCF7L2 STRA6 STRA6 Gata4 Gata4 TCF21 TCF21 GLI3 GLI3 SALL1 SALL1 Pitx2 Pitx2 FOXF2 FOXF2 ALDH1A2 ALDH1A2 PKDCC PKDCC TGFB2 TGFB2 VPS52 VPS52 CXCL8 CXCL8 FGFR2 FGFR2 GLI2 GLI2 HLX HLX MYB MYB RARB RARB RBPMS2 RBPMS2 SHOX2 SHOX2 PDGFRA PDGFRA PCSK5 PCSK5 HNF1B HNF1B TNF TNF LOC101972479 LOC101972479 ID2 ID2 IHH IHH SIX2 SIX2 RARRES2 RARRES2 LOC101972772 LOC101972772 OVOL2 OVOL2 FGF10 FGF10 TCF7 TCF7 SHH SHH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NIPBLNipped-B protein. (2803 aa)
TCF7L2Transcription factor 7 like 2. (514 aa)
STRA6Stimulated by retinoic acid 6. (662 aa)
Gata4GATA-type domain-containing protein. (212 aa)
TCF21Transcription factor 21. (179 aa)
GLI3GLI family zinc finger 3. (1582 aa)
SALL1Spalt like transcription factor 1. (1313 aa)
Pitx2Homeobox protein. (325 aa)
FOXF2Forkhead box F2. (384 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (294 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
VPS52VPS52 subunit of GARP complex. (723 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
FGFR2Fibroblast growth factor receptor. (823 aa)
GLI2GLI family zinc finger 2. (1540 aa)
HLXH2.0 like homeobox. (490 aa)
MYBMYB proto-oncogene, transcription factor. (753 aa)
RARBRetinoic acid receptor beta. (448 aa)
RBPMS2RNA binding protein, mRNA processing factor 2. (206 aa)
SHOX2Short stature homeobox 2. (319 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1880 aa)
HNF1BHNF1 homeobox B. (558 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
LOC101972479A_deaminase domain-containing protein. (338 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
IHHIndian hedgehog signaling molecule. (379 aa)
SIX2SIX homeobox 2. (296 aa)
RARRES2Retinoic acid receptor responder 2. (163 aa)
LOC101972772A_deaminase domain-containing protein. (352 aa)
OVOL2Ovo like zinc finger 2. (276 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
TCF7Transcription factor 7. (302 aa)
SHHSonic hedgehog signaling molecule. (370 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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