STRINGSTRING
I3M4W8_ICTTR I3M4W8_ICTTR PPP3CB PPP3CB GPER1 GPER1 ENY2 ENY2 Pde8b Pde8b ABCC8 ABCC8 ACVR1C ACVR1C PLA2G6 PLA2G6 TCF7L2 TCF7L2 SIDT2 SIDT2 RPTOR RPTOR ENSSTOP00000031124 ENSSTOP00000031124 FRMD4A FRMD4A RAP1GDS1 RAP1GDS1 ADCY8 ADCY8 MIDN MIDN LOC101963008 LOC101963008 PFKFB2 PFKFB2 EZR EZR SRI SRI IGF1 IGF1 SYT7 SYT7 SREBF1 SREBF1 ENSSTOP00000029088 ENSSTOP00000029088 ENSSTOP00000029050 ENSSTOP00000029050 TUNAR TUNAR FKBP1B FKBP1B MYO18A MYO18A ICA1 ICA1 NPFF NPFF NR1H2 NR1H2 ENSSTOP00000027973 ENSSTOP00000027973 NR1H3 NR1H3 KCNB1 KCNB1 PDE1C PDE1C HNF4A HNF4A Dph3 Dph3 TCIRG1 TCIRG1 ENSSTOP00000027065 ENSSTOP00000027065 CRHR2 CRHR2 Nadk Nadk JAGN1 JAGN1 FAM3D FAM3D SRCIN1 SRCIN1 LOC101978624 LOC101978624 ATG7 ATG7 ZNF384 ZNF384 SIRT6 SIRT6 ABAT ABAT MYH10 MYH10 Oga Oga PTGER3 PTGER3 Mpc2 Mpc2 IDUA IDUA BAIAP3 BAIAP3 MCU MCU Capn10 Capn10 CDK16 CDK16 KIF5B KIF5B ANO1 ANO1 ARRB1 ARRB1 GPLD1 GPLD1 PAM PAM MYT1 MYT1 ADTRP ADTRP GHRL GHRL GPR68 GPR68 PPARD PPARD NOS1 NOS1 NCOA6 NCOA6 Hcar2 Hcar2 ARF6 ARF6 PHPT1 PHPT1 C1qtnf3 C1qtnf3 CNR1 CNR1 PFKL PFKL OSBP OSBP MTNR1A MTNR1A TGFB3 TGFB3 FGA FGA TLR2 TLR2 TRH TRH I3NCA7_ICTTR I3NCA7_ICTTR PDX1 PDX1 I3NB10_ICTTR I3NB10_ICTTR F2RL1 F2RL1 LOC101959054 LOC101959054 ADAM9 ADAM9 BIRC5 BIRC5 GPR39 GPR39 ANXA1 ANXA1 LOC101958662 LOC101958662 TM7SF3 TM7SF3 MADD MADD TRPM4 TRPM4 FOXA2 FOXA2 PTPN11 PTPN11 INHBB INHBB LEPR LEPR RAB34 RAB34 PTGER4 PTGER4 DOC2B DOC2B PRKCQ PRKCQ LOC101960206 LOC101960206 PIM3 PIM3 PARD6A PARD6A ADRB1 ADRB1 IRS1 IRS1 I3N090_ICTTR I3N090_ICTTR ARFIP1 ARFIP1 Tbc1d1 Tbc1d1 TLR4 TLR4 I3MZU0_ICTTR I3MZU0_ICTTR TRPM2 TRPM2 KCNJ11 KCNJ11 NOS2 NOS2 Ins Ins DRD4 DRD4 PTPMT1 PTPMT1 ZBED6 ZBED6 ABCG1 ABCG1 ERP29 ERP29 DRD3 DRD3 SFRP1 SFRP1 ARNTL ARNTL SLC25A22 SLC25A22 I3MVL6_ICTTR I3MVL6_ICTTR CD2AP CD2AP SLC9B2 SLC9B2 CDV3 CDV3 NR0B2 NR0B2 ABCA12 ABCA12 ALOX5 ALOX5 Kcnn4 Kcnn4 SIRT1 SIRT1 TFAP2B TFAP2B LEP LEP SSTR5 SSTR5 EXOC1 EXOC1 Rab11fip5 Rab11fip5 GLRX GLRX PDE3B PDE3B RBP4 RBP4 PTPN23 PTPN23 GOLPH3 GOLPH3 CCL5 CCL5 GHSR GHSR SYBU SYBU ANXA5 ANXA5 LLGL1 LLGL1 AACS AACS IL12A IL12A GLUL GLUL C2cd2l C2cd2l CHGA CHGA HMGN3 HMGN3 PIK3C3 PIK3C3 RHBDF2 RHBDF2 LRP1 LRP1 LLGL2 LLGL2 TNF TNF CPT1A CPT1A Glud1 Glud1 PICK1 PICK1 PPARG PPARG PRKCE PRKCE NKX6-1 NKX6-1 RFX6 RFX6 LRP5 LRP5 NEO1 NEO1 STXBP4 STXBP4 Myrip Myrip DNM1L DNM1L PPP3CA PPP3CA NR1H4 NR1H4 EPHA5 EPHA5 Psmd9 Psmd9 SEC24A SEC24A KLF7 KLF7 RHBDF1 RHBDF1 UCP2 UCP2 SLC30A8 SLC30A8 PCSK1 PCSK1 VSNL1 VSNL1 TREM2 TREM2 SYT9 SYT9 FGB FGB CCN3 CCN3 STXBP5L STXBP5L TGFB1 TGFB1 CARTPT CARTPT P2RX7 P2RX7 SIRT4 SIRT4 RPH3AL RPH3AL Foxo1 Foxo1 LOC101968188 LOC101968188 HMGCR HMGCR HMMR HMMR CACNA1E CACNA1E SYT4 SYT4 ANKRD1 ANKRD1 APBB1 APBB1 MTNR1B MTNR1B MMP13 MMP13 PER2 PER2 OR51E2 OR51E2 BAD BAD Tardbp Tardbp F2R F2R WLS WLS STXBP5 STXBP5 IL13 IL13 FBN1 FBN1 CD200 CD200 AHI1 AHI1 PCK2 PCK2 Tmed10 Tmed10 Rest Rest RFX3 RFX3 I3M8U5_ICTTR I3M8U5_ICTTR EIPR1 EIPR1 RAC1 RAC1 NKX6-2 NKX6-2 EGFR EGFR JAK2 JAK2 CYP51A1 CYP51A1 GLP1R GLP1R NR1D1 NR1D1 RSAD2 RSAD2 NMU NMU SLC16A1 SLC16A1 ATP13A2 ATP13A2 VAMP8 VAMP8 CASK CASK MYOM1 MYOM1 I3M6M8_ICTTR I3M6M8_ICTTR I3M6L1_ICTTR I3M6L1_ICTTR Rab11fip1 Rab11fip1 SYTL4 SYTL4 NDUFAF2 NDUFAF2 ACSL4 ACSL4 CRH CRH TRPA1 TRPA1 IL12B IL12B GCG GCG Hif1a Hif1a EFNA5 EFNA5 HNF1A HNF1A EXPH5 EXPH5 GIP GIP VPS35 VPS35 DRD2 DRD2 SERGEF SERGEF SLC12A2 SLC12A2 GOLPH3L GOLPH3L GCK GCK ENSA ENSA IDH2 IDH2 DNAJC1 DNAJC1 VEGFC VEGFC IL1B IL1B IL1A IL1A LRRC8A LRRC8A APBB3 APBB3 PFKM PFKM C1QTNF12 C1QTNF12 RAPGEF4 RAPGEF4 PPID PPID RHBDD3 RHBDD3 HADH HADH TGFB2 TGFB2 UQCC2 UQCC2 BLK BLK STX4 STX4 OPRM1 OPRM1 NLGN2 NLGN2 Pde4c Pde4c FGG FGG P3H1 P3H1 ADCY5 ADCY5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I3M4W8_ICTTRUncharacterized protein. (207 aa)
PPP3CBSerine/threonine-protein phosphatase. (523 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa)
Pde8bPhosphodiesterase. (865 aa)
ABCC8ATP binding cassette subfamily C member 8. (1624 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
PLA2G6Phospholipase A2 group VI. (807 aa)
TCF7L2Transcription factor 7 like 2. (514 aa)
SIDT2SID1 transmembrane family member 2. (853 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1335 aa)
ENSSTOP00000031124Uncharacterized protein. (296 aa)
FRMD4AFERM domain containing 4A. (1055 aa)
RAP1GDS1Rap1 GTPase-GDP dissociation stimulator 1. (607 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
MIDNMidnolin. (423 aa)
LOC101963008GOLD domain-containing protein. (188 aa)
PFKFB26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2. (556 aa)
EZREzrin. (604 aa)
SRISorcin. (198 aa)
IGF1Insulin like growth factor 1. (166 aa)
SYT7Synaptotagmin 7. (688 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1152 aa)
ENSSTOP00000029088Rab-GAP TBC domain-containing protein. (355 aa)
ENSSTOP00000029050Uncharacterized protein. (117 aa)
TUNARTCL1 upstream neural differentiation-associated RNA. (61 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
MYO18AMyosin XVIIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2085 aa)
ICA1Islet cell autoantigen 1. (482 aa)
NPFFNeuropeptide FF-amide peptide precursor. (109 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (459 aa)
ENSSTOP00000027973Uncharacterized protein. (5517 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (444 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (859 aa)
PDE1CPhosphodiesterase. (769 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
Dph3DPH-type MB domain-containing protein. (82 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (861 aa)
ENSSTOP00000027065Uncharacterized protein. (55 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (436 aa)
NadkUncharacterized protein. (447 aa)
JAGN1Jagunal homolog 1. (183 aa)
FAM3DFamily with sequence similarity 3 member D. (225 aa)
SRCIN1SRC kinase signaling inhibitor 1. (1234 aa)
LOC101978624Uncharacterized protein. (906 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (726 aa)
ZNF384Zinc finger protein 384. (573 aa)
SIRT6Sirtuin 6. (351 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
OgaUncharacterized protein. (565 aa)
PTGER3Prostaglandin E receptor 3. (388 aa)
Mpc2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (90 aa)
IDUAIduronidase alpha-L-. (639 aa)
BAIAP3BAI1 associated protein 3. (1152 aa)
MCUMitochondrial calcium uniporter. (302 aa)
Capn10Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (644 aa)
CDK16Cyclin dependent kinase 16; Belongs to the protein kinase superfamily. (496 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
ANO1Anoctamin. (997 aa)
ARRB1Arrestin beta 1. (418 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (896 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (979 aa)
MYT1Myelin transcription factor 1. (1148 aa)
ADTRPAndrogen dependent TFPI regulating protein. (219 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (375 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1329 aa)
NCOA6Nuclear receptor coactivator 6. (2064 aa)
Hcar2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (352 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
PHPT1Phosphohistidine phosphatase 1. (125 aa)
C1qtnf3C1q domain-containing protein. (246 aa)
CNR1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (473 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
OSBPOxysterol-binding protein; Belongs to the OSBP family. (730 aa)
MTNR1AMelatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family. (353 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
FGAFibrinogen alpha chain. (788 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (784 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (240 aa)
I3NCA7_ICTTRCalpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (240 aa)
PDX1Pancreatic and duodenal homeobox 1. (283 aa)
I3NB10_ICTTRMitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (117 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
LOC101959054Uncharacterized protein. (395 aa)
ADAM9ADAM metallopeptidase domain 9. (782 aa)
BIRC5Baculoviral IAP repeat containing 5. (142 aa)
GPR39G protein-coupled receptor 39; Belongs to the G-protein coupled receptor 1 family. (456 aa)
ANXA1Annexin. (346 aa)
LOC101958662DPH-type MB domain-containing protein. (82 aa)
TM7SF3Transmembrane 7 superfamily member 3. (570 aa)
MADDMAP kinase activating death domain. (1597 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1173 aa)
FOXA2Forkhead box A2. (463 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
INHBBInhibin subunit beta B. (336 aa)
LEPRLeptin receptor. (1148 aa)
RAB34RAB34, member RAS oncogene family. (259 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (488 aa)
DOC2BDouble C2 domain beta. (356 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
LOC101960206Uncharacterized protein. (207 aa)
PIM3Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (297 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
ADRB1Adrenoceptor beta 1. (418 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
I3N090_ICTTRUncharacterized protein. (207 aa)
ARFIP1ADP ribosylation factor interacting protein 1. (373 aa)
Tbc1d1Uncharacterized protein. (1233 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (840 aa)
I3MZU0_ICTTRLipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (138 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1499 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1070 aa)
InsInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (374 aa)
PTPMT1Protein tyrosine phosphatase mitochondrial 1. (201 aa)
ZBED6Zinc finger BED-type containing 6. (979 aa)
ABCG1ATP binding cassette subfamily G member 1. (666 aa)
ERP29Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. (261 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (445 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (633 aa)
SLC25A22Solute carrier family 25 member 22; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa)
I3MVL6_ICTTRUncharacterized protein. (192 aa)
CD2APCD2 associated protein. (637 aa)
SLC9B2Solute carrier family 9 member B2. (509 aa)
CDV3CDV3 homolog. (266 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (260 aa)
ABCA12ATP binding cassette subfamily A member 12. (2598 aa)
ALOX5Arachidonate 5-lipoxygenase. (663 aa)
Kcnn4CaMBD domain-containing protein. (167 aa)
SIRT1Sirtuin 1. (602 aa)
TFAP2BTranscription factor AP-2 beta. (460 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
SSTR5Somatostatin receptor 5; Belongs to the G-protein coupled receptor 1 family. (363 aa)
EXOC1Exocyst complex component 1. (901 aa)
Rab11fip5Uncharacterized protein. (1315 aa)
GLRXGlutaredoxin. (107 aa)
PDE3BPhosphodiesterase. (1046 aa)
RBP4Apolipoprotein D. (163 aa)
PTPN23Protein tyrosine phosphatase non-receptor type 23. (1639 aa)
GOLPH3Golgi phosphoprotein 3. (298 aa)
CCL5C-C motif chemokine ligand 5. (91 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
SYBUSyntabulin. (780 aa)
ANXA5Annexin. (321 aa)
LLGL1LLGL scribble cell polarity complex component 1. (1045 aa)
AACSAcetoacetyl-CoA synthetase. (672 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa)
GLULGlutamine synthetase. (373 aa)
C2cd2lUncharacterized protein. (267 aa)
CHGAChromogranin A. (432 aa)
HMGN3High mobility group nucleosomal binding domain 3. (128 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (783 aa)
RHBDF2Rhomboid 5 homolog 2. (826 aa)
LRP1LDL receptor related protein 1. (4508 aa)
LLGL2LLGL scribble cell polarity complex component 2. (1024 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
Glud1ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (264 aa)
PICK1Protein interacting with PRKCA 1. (416 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
NKX6-1NK6 homeobox 1. (366 aa)
RFX6Regulatory factor X6. (928 aa)
LRP5Uncharacterized protein. (1516 aa)
NEO1Neogenin 1. (1440 aa)
STXBP4Syntaxin binding protein 4. (558 aa)
MyripMyosin VIIA and Rab interacting protein. (852 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
PPP3CASerine/threonine-protein phosphatase. (511 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (487 aa)
EPHA5EPH receptor A5. (1039 aa)
Psmd9PDZ domain-containing protein. (223 aa)
SEC24ASEC24 homolog A, COPII coat complex component. (1091 aa)
KLF7Kruppel like factor 7. (302 aa)
RHBDF1Rhomboid 5 homolog 1. (855 aa)
UCP2Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
SLC30A8Solute carrier family 30 member 8. (368 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (753 aa)
VSNL1Visinin like 1. (191 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (262 aa)
SYT9Synaptotagmin 9. (491 aa)
FGBFibrinogen beta chain. (478 aa)
CCN3Cellular communication network factor 3. (350 aa)
STXBP5LSyntaxin binding protein 5 like. (1186 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
CARTPTCART prepropeptide. (129 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (596 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
RPH3ALRabphilin 3A like (without C2 domains). (302 aa)
Foxo1Forkhead box protein O1; Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalc [...] (535 aa)
LOC101968188Ig-like domain-containing protein. (266 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa)
HMMRHyaluronan mediated motility receptor. (713 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2312 aa)
SYT4Synaptotagmin 4. (424 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
APBB1Amyloid beta precursor protein binding family B member 1. (708 aa)
MTNR1BMelatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. (364 aa)
MMP13Matrix metallopeptidase 13. (417 aa)
PER2Period circadian regulator 2. (1297 aa)
OR51E2Olfactory receptor. (320 aa)
BADBCL2 associated agonist of cell death. (208 aa)
TardbpUncharacterized protein. (414 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
WLSWnt ligand secretion mediator. (541 aa)
STXBP5Syntaxin binding protein 5. (964 aa)
IL13Interleukin 13. (130 aa)
FBN1Fibrillin 1. (2736 aa)
CD200CD200 molecule. (269 aa)
AHI1Abelson helper integration site 1. (1050 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
Tmed10GOLD domain-containing protein. (219 aa)
RestUncharacterized protein. (328 aa)
RFX3Regulatory factor X3. (749 aa)
I3M8U5_ICTTRPiwi domain-containing protein. (456 aa)
EIPR1EARP complex and GARP complex interacting protein 1. (387 aa)
RAC1Rac family small GTPase 1. (211 aa)
NKX6-2NK6 homeobox 2. (267 aa)
EGFRReceptor protein-tyrosine kinase. (1192 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
CYP51A1Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (473 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (611 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (361 aa)
NMUNeuromedin U. (170 aa)
SLC16A1Solute carrier family 16 member 1. (494 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1165 aa)
VAMP8Vesicle associated membrane protein 8. (141 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (930 aa)
MYOM1Myomesin 1. (1675 aa)
I3M6M8_ICTTRRRM domain-containing protein. (122 aa)
I3M6L1_ICTTRABC transmembrane type-1 domain-containing protein. (528 aa)
Rab11fip1Uncharacterized protein. (644 aa)
SYTL4Synaptotagmin like 4. (672 aa)
NDUFAF2NADH:ubiquinone oxidoreductase complex assembly factor 2. (204 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
CRHCorticotropin releasing hormone. (180 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1. (1044 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa)
GCGGlucagon. (180 aa)
Hif1aUncharacterized protein. (821 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (186 aa)
HNF1AHNF1 homeobox A. (449 aa)
EXPH5Exophilin 5. (2018 aa)
GIPGastric inhibitory polypeptide. (140 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
SERGEFSecretion regulating guanine nucleotide exchange factor. (459 aa)
SLC12A2Solute carrier family 12 member 2. (1108 aa)
GOLPH3LGolgi phosphoprotein 3 like. (285 aa)
GCKPhosphotransferase. (467 aa)
ENSAEndosulfine alpha; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (121 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
DNAJC1DnaJ heat shock protein family (Hsp40) member C1. (545 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (417 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (200 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (268 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (810 aa)
APBB3Amyloid beta precursor protein binding family B member 3. (486 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
C1QTNF12C1q and TNF related 12. (311 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (985 aa)
PPIDPeptidylprolyl isomerase D. (370 aa)
RHBDD3Rhomboid domain containing 3. (392 aa)
HADHHydroxyacyl-CoA dehydrogenase. (314 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
UQCC2Ubiquinol-cytochrome c reductase complex assembly factor 2. (136 aa)
BLKTyrosine-protein kinase. (499 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (298 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (326 aa)
NLGN2Neuroligin 2. (744 aa)
Pde4cPhosphodiesterase. (563 aa)
FGGFibrinogen gamma chain. (445 aa)
P3H1Prolyl 3-hydroxylase 1. (760 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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