STRINGSTRING
SOCS1 SOCS1 PPP2R5B PPP2R5B CCK CCK WNT3A WNT3A ALKAL2 ALKAL2 SOCS5 SOCS5 IGF2 IGF2 LOC101960206 LOC101960206 NF2 NF2 PECAM1 PECAM1 NEURL1 NEURL1 NTF3 NTF3 ADNP ADNP SH3BP5L SH3BP5L FGF10 FGF10 I3N090_ICTTR I3N090_ICTTR LOC101962730 LOC101962730 Ctf1 Ctf1 NRG2 NRG2 TLR4 TLR4 BMP6 BMP6 CSF1R CSF1R ADRA1A ADRA1A FBXW7 FBXW7 Fam72a Fam72a AGT AGT RAP2B RAP2B NOD2 NOD2 SFRP1 SFRP1 FGF7 FGF7 I3MVL6_ICTTR I3MVL6_ICTTR I3MV62_ICTTR I3MV62_ICTTR CAV1 CAV1 CNTF CNTF LEP LEP IL18 IL18 VTN VTN SRC SRC IL2 IL2 ADIPOQ ADIPOQ CNTN1 CNTN1 IL23A IL23A ZZEF1 ZZEF1 CLCF1 CLCF1 PRNP PRNP IL34 IL34 RIPK2 RIPK2 IFNAR1 IFNAR1 SH3BP5 SH3BP5 IL12A IL12A HAX1 HAX1 DGKQ DGKQ HES5 HES5 GATA1 GATA1 GAS6 GAS6 DMTN DMTN Plpp3 Plpp3 GREM1 GREM1 PARP14 PARP14 OSBP OSBP CAV2 CAV2 SAMSN1 SAMSN1 Pdcl3 Pdcl3 LOC101966442 LOC101966442 CD4 CD4 CD40 CD40 PDGFRB PDGFRB GPRC5B GPRC5B BST1 BST1 GHRL GHRL ERBB3 ERBB3 LRP8 LRP8 HBEGF HBEGF ARRB2 ARRB2 ARL2BP ARL2BP PSEN2 PSEN2 DLG3 DLG3 STAP1 STAP1 NEDD9 NEDD9 DLG4 DLG4 TGFA TGFA PSEN1 PSEN1 GPRC5A GPRC5A CD36 CD36 ENSSTOP00000025794 ENSSTOP00000025794 ICAM1 ICAM1 PTPRC PTPRC CNOT7 CNOT7 HSF1 HSF1 TNK2 TNK2 SRCIN1 SRCIN1 MUSK MUSK APP APP CTNND1 CTNND1 ENSSTOP00000027114 ENSSTOP00000027114 HNF4A HNF4A FGF8 FGF8 HYAL2 HYAL2 IQGAP1 IQGAP1 IL9 IL9 PTPRJ PTPRJ EPHA7 EPHA7 ABI1 ABI1 KITLG KITLG ENSSTOP00000029018 ENSSTOP00000029018 LYN LYN MLST8 MLST8 IL24 IL24 PTPN6 PTPN6 IGF1 IGF1 AGRN AGRN PTK2B PTK2B HPX HPX AFAP1L2 AFAP1L2 EFNA1 EFNA1 IL7 IL7 LRP4 LRP4 IL21 IL21 BANK1 BANK1 MTOR MTOR NRG1 NRG1 FGFR3 FGFR3 LOC101968601 LOC101968601 VEGFB VEGFB I3MM52_ICTTR I3MM52_ICTTR BTC BTC CSF2 CSF2 EPO EPO NRP1 NRP1 ITGB1 ITGB1 PARP9 PARP9 ISL1 ISL1 HDAC2 HDAC2 PRKCE PRKCE HRG HRG IL22RA2 IL22RA2 ZFYVE28 ZFYVE28 NCAPG2 NCAPG2 CBLB CBLB ZGPAT ZGPAT CASS4 CASS4 RELN RELN PDGFRA PDGFRA SOCS3 SOCS3 Osm Osm TREM2 TREM2 TNFSF18 TNFSF18 TNFRSF1A TNFRSF1A APLP2 APLP2 HCLS1 HCLS1 ERRFI1 ERRFI1 IRF1 IRF1 AREG AREG VEGFA VEGFA LRRK1 LRRK1 CD74 CD74 THBS4 THBS4 IL6R IL6R IL5 IL5 SPINK1 SPINK1 ERBB4 ERBB4 CD81 CD81 PIBF1 PIBF1 TMEM102 TMEM102 EREG EREG UNC119 UNC119 ARHGEF2 ARHGEF2 RASA1 RASA1 IL11 IL11 EHD4 EHD4 KIT KIT SEMA4D SEMA4D SH2B3 SH2B3 ITGB2 ITGB2 MVP MVP PDGFC PDGFC DUSP22 DUSP22 ENPP2 ENPP2 IL9R IL9R SFRP2 SFRP2 GGNBP2 GGNBP2 ALK ALK Itgb3 Itgb3 HTR2A HTR2A EPHA4 EPHA4 ALKAL1 ALKAL1 HGF HGF EPGN EPGN ERCC6 ERCC6 PDGFA PDGFA VPS25 VPS25 IBTK IBTK PDGFD PDGFD SOCS4 SOCS4 ADAM17 ADAM17 PRKCD PRKCD ACVR1 ACVR1 CRLF1 CRLF1 EFNA5 EFNA5 I3M4W8_ICTTR I3M4W8_ICTTR DOK7 DOK7 IL31RA IL31RA IL12B IL12B IL6ST IL6ST INPP5F INPP5F CSF3 CSF3 CBL CBL THY1 THY1 RICTOR RICTOR IL15 IL15 PLCG2 PLCG2 SYK SYK LIF LIF NCF1 NCF1 JAK2 JAK2 EGFR EGFR FBXW9 FBXW9 RACK1 RACK1 FYN FYN PTPN2 PTPN2 PTK6 PTK6 IL13 IL13 ANGPT1 ANGPT1 ITGA5 ITGA5 NOX4 NOX4 PAK2 PAK2 TAL1 TAL1 DVL2 DVL2 Tsg101 Tsg101 LOC101974931 LOC101974931 PTGER4 PTGER4 CSPG4 CSPG4 PDGFB PDGFB CHMP6 CHMP6 GDNF GDNF TP53 TP53 PTPN11 PTPN11 HES1 HES1 PTPN1 PTPN1 ANGPT4 ANGPT4 PTPRZ1 PTPRZ1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOCS1Suppressor of cytokine signaling 1. (211 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
CCKCholecystokinin. (115 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ALKAL2ALK and LTK ligand 2. (131 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
IGF2Insulin like growth factor 2. (180 aa)
LOC101960206Uncharacterized protein. (207 aa)
NF2Neurofibromin 2. (596 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (740 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
ADNPActivity dependent neuroprotector homeobox. (1103 aa)
SH3BP5LSH3 binding domain protein 5 like. (393 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
I3N090_ICTTRUncharacterized protein. (207 aa)
LOC101962730Uncharacterized protein. (2398 aa)
Ctf1Uncharacterized protein. (204 aa)
NRG2Neuregulin 2. (767 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (840 aa)
BMP6Bone morphogenetic protein 6. (507 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (975 aa)
ADRA1AAdrenoceptor alpha 1A. (466 aa)
FBXW7F-box and WD repeat domain containing 7. (713 aa)
Fam72aUncharacterized protein. (149 aa)
AGTAngiotensinogen; Belongs to the serpin family. (477 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1014 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
I3MVL6_ICTTRUncharacterized protein. (192 aa)
I3MV62_ICTTRPhosducin domain-containing protein. (198 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
CNTFCiliary neurotrophic factor. (199 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
VTNSMB domain-containing protein. (466 aa)
SRCTyrosine-protein kinase. (541 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
CNTN1Contactin 1. (627 aa)
IL23AInterleukin 23 subunit alpha. (185 aa)
ZZEF1Zinc finger ZZ-type and EF-hand domain containing 1. (2953 aa)
CLCF1Cardiotrophin like cytokine factor 1. (219 aa)
PRNPMajor prion protein; Belongs to the prion family. (247 aa)
IL34Interleukin 34. (240 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (490 aa)
SH3BP5SH3 domain binding protein 5. (390 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (253 aa)
DGKQDiacylglycerol kinase. (924 aa)
HES5Hes family bHLH transcription factor 5. (141 aa)
GATA1GATA binding protein 1. (413 aa)
GAS6Growth arrest specific 6. (654 aa)
DMTNDematin actin binding protein. (405 aa)
Plpp3acidPPc domain-containing protein. (312 aa)
GREM1Gremlin. (184 aa)
PARP14Poly [ADP-ribose] polymerase. (1803 aa)
OSBPOxysterol-binding protein; Belongs to the OSBP family. (730 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
SAMSN1SAM domain, SH3 domain and nuclear localization signals 1. (373 aa)
Pdcl3Phosducin domain-containing protein. (240 aa)
LOC101966442Uncharacterized protein. (370 aa)
CD4CD4 molecule. (451 aa)
CD40CD40 molecule. (284 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1112 aa)
GPRC5BG protein-coupled receptor class C group 5 member B. (411 aa)
BST1Bone marrow stromal cell antigen 1. (311 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1248 aa)
LRP8LDL receptor related protein 8. (940 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
ARRB2Arrestin beta 2. (409 aa)
ARL2BPADP ribosylation factor like GTPase 2 binding protein. (163 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (867 aa)
STAP1Signal transducing adaptor family member 1. (297 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (834 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
TGFATransforming growth factor alpha. (159 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
GPRC5AG protein-coupled receptor class C group 5 member A. (357 aa)
CD36CD36 molecule; Belongs to the CD36 family. (473 aa)
ENSSTOP00000025794Uncharacterized protein. (78 aa)
ICAM1Intercellular adhesion molecule 1. (531 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1180 aa)
CNOT7Uncharacterized protein. (285 aa)
HSF1Heat shock transcription factor 1. (545 aa)
TNK2Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1055 aa)
SRCIN1SRC kinase signaling inhibitor 1. (1234 aa)
MUSKMuscle associated receptor tyrosine kinase. (884 aa)
APPAmyloid beta precursor protein. (739 aa)
CTNND1Catenin delta 1. (967 aa)
ENSSTOP00000027114Uncharacterized protein. (91 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
HYAL2Hyaluronidase. (472 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
IL9Interleukin 9. (144 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1197 aa)
EPHA7EPH receptor A7. (998 aa)
ABI1Abl interactor 1. (508 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
ENSSTOP00000029018UEV domain-containing protein. (97 aa)
LYNTyrosine-protein kinase. (512 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
IL24Interleukin 24. (220 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
IGF1Insulin like growth factor 1. (166 aa)
AGRNAgrin. (1964 aa)
PTK2BProtein tyrosine kinase 2 beta. (968 aa)
HPXHemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (462 aa)
AFAP1L2Actin filament associated protein 1 like 2. (846 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (159 aa)
LRP4LDL receptor related protein 4. (1905 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (158 aa)
BANK1B cell scaffold protein with ankyrin repeats 1. (726 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2577 aa)
NRG1Neuregulin 1. (700 aa)
FGFR3Fibroblast growth factor receptor. (804 aa)
LOC101968601Uncharacterized protein. (80 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (184 aa)
I3MM52_ICTTRIg-like domain-containing protein. (222 aa)
BTCBetacellulin. (143 aa)
CSF2Colony stimulating factor 2. (138 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (820 aa)
ISL1ISL LIM homeobox 1. (349 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
HRGHistidine rich glycoprotein. (531 aa)
IL22RA2Interleukin 22 receptor subunit alpha 2. (231 aa)
ZFYVE28Zinc finger FYVE-type containing 28. (910 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1139 aa)
CBLBCbl proto-oncogene B. (985 aa)
ZGPATZinc finger CCCH-type and G-patch domain containing. (465 aa)
CASS4Cas scaffold protein family member 4. (752 aa)
RELNReelin. (3416 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
SOCS3Suppressor of cytokine signaling 3. (227 aa)
OsmUncharacterized protein. (214 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (262 aa)
TNFSF18TNF superfamily member 18. (172 aa)
TNFRSF1ATNF receptor superfamily member 1A. (437 aa)
APLP2Amyloid beta precursor like protein 2. (760 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (478 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (459 aa)
IRF1Interferon regulatory factor. (326 aa)
AREGAmphiregulin. (252 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (392 aa)
LRRK1Leucine rich repeat kinase 1. (2014 aa)
CD74CD74 molecule. (279 aa)
THBS4Thrombospondin 4. (961 aa)
IL6RInterleukin 6 receptor. (409 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
SPINK1Serine peptidase inhibitor, Kazal type 1. (68 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
CD81Tetraspanin. (214 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (757 aa)
TMEM102Transmembrane protein 102. (510 aa)
EREGEpiregulin. (163 aa)
UNC119Unc-119 lipid binding chaperone. (240 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (869 aa)
RASA1RAS p21 protein activator 1. (1030 aa)
IL11Interleukin 11. (199 aa)
EHD4EH domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (541 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (747 aa)
SH2B3SH2B adaptor protein 3. (429 aa)
ITGB2Integrin beta. (769 aa)
MVPMajor vault protein. (759 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (344 aa)
DUSP22Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (205 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (915 aa)
IL9RInterleukin 9 receptor. (465 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
GGNBP2Gametogenetin binding protein 2. (738 aa)
ALKTyrosine-protein kinase receptor. (1612 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (792 aa)
HTR2A5-hydroxytryptamine receptor 2A. (472 aa)
EPHA4EPH receptor A4. (986 aa)
ALKAL1ALK and LTK ligand 1. (128 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa)
EPGNEpithelial mitogen. (153 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1521 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
VPS25Vacuolar protein sorting 25 homolog. (176 aa)
IBTKInhibitor of Bruton tyrosine kinase. (1354 aa)
PDGFDPlatelet derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (370 aa)
SOCS4Suppressor of cytokine signaling 4. (439 aa)
ADAM17ADAM metallopeptidase domain 17. (811 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
CRLF1Cytokine receptor like factor 1. (362 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (186 aa)
I3M4W8_ICTTRUncharacterized protein. (207 aa)
DOK7Docking protein 7. (576 aa)
IL31RAInterleukin 31 receptor A. (704 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa)
IL6STInterleukin 6 signal transducer. (928 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1110 aa)
CSF3Colony stimulating factor 3. (210 aa)
CBLCbl proto-oncogene. (870 aa)
THY1Thy-1 cell surface antigen. (162 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1660 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (134 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
SYKTyrosine-protein kinase. (626 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
NCF1Neutrophil cytosolic factor 1. (405 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
EGFRReceptor protein-tyrosine kinase. (1192 aa)
FBXW9F-box and WD repeat domain containing 9. (462 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
FYNTyrosine-protein kinase. (537 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (389 aa)
PTK6Tyrosine-protein kinase. (450 aa)
IL13Interleukin 13. (130 aa)
ANGPT1Angiopoietin 1. (497 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1105 aa)
NOX4NADPH oxidase 4. (578 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
Tsg101SB domain-containing protein. (325 aa)
LOC101974931Tyrosine-protein phosphatase non-receptor type. (433 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (488 aa)
CSPG4Chondroitin sulfate proteoglycan 4. (2322 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (211 aa)
CHMP6Charged multivesicular body protein 6. (201 aa)
GDNFGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (212 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (413 aa)
ANGPT4Angiopoietin 4. (496 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2277 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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