STRINGSTRING
BCR BCR ARG2 ARG2 DNAJA3 DNAJA3 FER FER CLEC4G CLEC4G LOXL3 LOXL3 CACTIN CACTIN TGFB2 TGFB2 TBX21 TBX21 DUSP22 DUSP22 METTL3 METTL3 PARP3 PARP3 VSIG4 VSIG4 TTLL12 TTLL12 Ahr Ahr Rabgef1 Rabgef1 Tap2 Tap2 TAP1 TAP1 DRD2 DRD2 OAS3 OAS3 CD96 CD96 GRN GRN FOXP3 FOXP3 FCRLB FCRLB TRIM21 TRIM21 IL12B IL12B PGLYRP3 PGLYRP3 Ndfip1 Ndfip1 PSMA1 PSMA1 HLX HLX IL10 IL10 THOC1 THOC1 DHX58 DHX58 C4BPA C4BPA IRAK3 IRAK3 SLAMF1 SLAMF1 SLAMF8 SLAMF8 PTPN2 PTPN2 JAK3 JAK3 TNFAIP3 TNFAIP3 Banf1 Banf1 Nlrc3 Nlrc3 I3NHR2_ICTTR I3NHR2_ICTTR ARRB2 ARRB2 TRIM27 TRIM27 MUL1 MUL1 TRAFD1 TRAFD1 CRK CRK FGL2 FGL2 BCL6 BCL6 IL33 IL33 KLRD1 KLRD1 ENSSTOP00000026236 ENSSTOP00000026236 PTPRC PTPRC HMOX1 HMOX1 SERPING1 SERPING1 CNOT7 CNOT7 NLRP6 NLRP6 ENSSTOP00000027114 ENSSTOP00000027114 SUSD4 SUSD4 ABR ABR YTHDF3 YTHDF3 ENSSTOP00000029572 ENSSTOP00000029572 GPX2 GPX2 PTPN6 PTPN6 ENSSTOP00000030092 ENSSTOP00000030092 ENSSTOP00000030168 ENSSTOP00000030168 NLRX1 NLRX1 ENSSTOP00000030875 ENSSTOP00000030875 USP15 USP15 COL3A1 COL3A1 ENSSTOP00000031571 ENSSTOP00000031571 PPP3CB PPP3CB MMP12 MMP12 IL27RA IL27RA DCST1 DCST1 SELENOS SELENOS LOC101968188 LOC101968188 NLRC5 NLRC5 TNFSF18 TNFSF18 TREM2 TREM2 MKRN2 MKRN2 RC3H2 RC3H2 INPP5D INPP5D Cd59 Cd59 ADCYAP1 ADCYAP1 CLEC12B CLEC12B DUSP10 DUSP10 ATG12 ATG12 PSMB4 PSMB4 PPARG PPARG CSMD3 CSMD3 STAT6 STAT6 LOC101967274 LOC101967274 ADAR ADAR I3MMN9_ICTTR I3MMN9_ICTTR I3MMP4_ICTTR I3MMP4_ICTTR HFE HFE TYRO3 TYRO3 STAT2 STAT2 RC3H1 RC3H1 IL2 IL2 IL13RA2 IL13RA2 ATG5 ATG5 SMAD7 SMAD7 PDCD1 PDCD1 NOD2 NOD2 Ins Ins FOXJ1 FOXJ1 ACOD1 ACOD1 NCKAP1L NCKAP1L OLFM4 OLFM4 PGLYRP1 PGLYRP1 ZBTB7B ZBTB7B LOC101973215 LOC101973215 SAMHD1 SAMHD1 TREX1 TREX1 LOC101957374 LOC101957374 GPR17 GPR17 NPY5R NPY5R ALOX15 ALOX15 Fcgr2b Fcgr2b LOC101968765 LOC101968765 IL1RL1 IL1RL1 CTLA4 CTLA4 CD84 CD84 PGLYRP2 PGLYRP2 SPI1 SPI1 ANXA1 ANXA1 SOCS5 SOCS5 ZC3H12A ZC3H12A YTHDF2 YTHDF2 Lyar Lyar PARP14 PARP14 GFER GFER IL4R IL4R SAMSN1 SAMSN1 OTOP1 OTOP1 Cd55 Cd55 LGALS3 LGALS3 NMI NMI Usp18 Usp18 GPX1 GPX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BCRBCR activator of RhoGEF and GTPase. (1283 aa)
ARG2Arginase. (354 aa)
DNAJA3DnaJ heat shock protein family (Hsp40) member A3. (479 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
CLEC4GC-type lectin domain family 4 member G. (295 aa)
LOXL3Lysyl oxidase like 3. (753 aa)
CACTINCactin, spliceosome C complex subunit. (720 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TBX21T-box transcription factor 21. (535 aa)
DUSP22Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (205 aa)
METTL3Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa)
PARP3Poly [ADP-ribose] polymerase. (529 aa)
VSIG4V-set and immunoglobulin domain containing 4. (399 aa)
TTLL12Tubulin tyrosine ligase like 12. (590 aa)
AhrUncharacterized protein. (848 aa)
Rabgef1Uncharacterized protein. (491 aa)
Tap2Uncharacterized protein. (703 aa)
TAP1Transporter 1, ATP binding cassette subfamily B member. (749 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
OAS32'-5'-oligoadenylate synthetase 3. (991 aa)
CD96CD96 molecule. (558 aa)
GRNGranulin precursor. (596 aa)
FOXP3Forkhead box P3. (431 aa)
FCRLBFc receptor like B. (430 aa)
TRIM21Tripartite motif containing 21. (477 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa)
PGLYRP3Peptidoglycan recognition protein 3. (346 aa)
Ndfip1Nedd4 family interacting protein 1. (229 aa)
PSMA1Proteasome subunit alpha type. (266 aa)
HLXH2.0 like homeobox. (490 aa)
IL10Interleukin 10. (178 aa)
THOC1THO complex 1. (657 aa)
DHX58DExH-box helicase 58. (678 aa)
C4BPAComplement component 4 binding protein alpha. (540 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (607 aa)
SLAMF1Signaling lymphocytic activation molecule family member 1. (335 aa)
SLAMF8SLAM family member 8. (298 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (389 aa)
JAK3Tyrosine-protein kinase. (1042 aa)
TNFAIP3TNF alpha induced protein 3. (776 aa)
Banf1Uncharacterized protein. (89 aa)
Nlrc3Uncharacterized protein. (397 aa)
I3NHR2_ICTTRUncharacterized protein. (435 aa)
ARRB2Arrestin beta 2. (409 aa)
TRIM27Tripartite motif containing 27. (513 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
TRAFD1TRAF-type zinc finger domain containing 1. (580 aa)
CRKCRK proto-oncogene, adaptor protein. (305 aa)
FGL2Fibrinogen like 2. (439 aa)
BCL6BCL6 transcription repressor. (706 aa)
IL33Interleukin 33. (264 aa)
KLRD1Killer cell lectin like receptor D1. (178 aa)
ENSSTOP00000026236Uncharacterized protein. (74 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1180 aa)
HMOX1Heme oxygenase 1. (288 aa)
SERPING1Serpin family G member 1; Belongs to the serpin family. (474 aa)
CNOT7Uncharacterized protein. (285 aa)
NLRP6NLR family pyrin domain containing 6. (880 aa)
ENSSTOP00000027114Uncharacterized protein. (91 aa)
SUSD4Sushi domain containing 4. (489 aa)
ABRABR activator of RhoGEF and GTPase. (871 aa)
YTHDF3YTH N6-methyladenosine RNA binding protein 3. (588 aa)
ENSSTOP00000029572Uncharacterized protein. (198 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (189 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
ENSSTOP00000030092Uncharacterized protein. (1408 aa)
ENSSTOP00000030168Uncharacterized protein. (76 aa)
NLRX1NLR family member X1. (975 aa)
ENSSTOP00000030875Uncharacterized protein. (528 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
COL3A1Collagen type III alpha 1 chain. (1462 aa)
ENSSTOP00000031571C-type lectin domain-containing protein. (138 aa)
PPP3CBSerine/threonine-protein phosphatase. (523 aa)
MMP12Matrix metallopeptidase 12. (477 aa)
IL27RAInterleukin 27 receptor subunit alpha. (569 aa)
DCST1DC-STAMP domain containing 1. (710 aa)
SELENOSSelenoprotein S. (189 aa)
LOC101968188Ig-like domain-containing protein. (266 aa)
NLRC5NLR family CARD domain containing 5. (1847 aa)
TNFSF18TNF superfamily member 18. (172 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (262 aa)
MKRN2Makorin ring finger protein 2. (415 aa)
RC3H2Ring finger and CCCH-type domains 2. (1188 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1213 aa)
Cd59UPAR/Ly6 domain-containing protein. (131 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
CLEC12BC-type lectin domain family 12 member B. (276 aa)
DUSP10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
CSMD3CUB and Sushi multiple domains 3. (3707 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
LOC101967274SERPIN domain-containing protein; Belongs to the serpin family. (375 aa)
ADARAdenosine deaminase RNA specific. (1165 aa)
I3MMN9_ICTTRSERPIN domain-containing protein; Belongs to the serpin family. (417 aa)
I3MMP4_ICTTRNUC domain-containing protein. (149 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (376 aa)
TYRO3TYRO3 protein tyrosine kinase. (890 aa)
STAT2Signal transducer and activator of transcription. (805 aa)
RC3H1Ring finger and CCCH-type domains 1. (1130 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
IL13RA2Interleukin 13 receptor subunit alpha 2. (388 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
PDCD1Programmed cell death 1. (288 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1014 aa)
InsInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
FOXJ1Forkhead box J1. (421 aa)
ACOD1Aconitate decarboxylase 1. (473 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
OLFM4Olfactomedin 4. (456 aa)
PGLYRP1Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (195 aa)
ZBTB7BZinc finger and BTB domain containing 7B. (539 aa)
LOC101973215SERPIN domain-containing protein; Belongs to the serpin family. (375 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (618 aa)
TREX1Three prime repair exonuclease 1. (304 aa)
LOC101957374SERPIN domain-containing protein; Belongs to the serpin family. (427 aa)
GPR17G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family. (338 aa)
NPY5RNeuropeptide Y receptor Y5. (446 aa)
ALOX15Arachidonate 15-lipoxygenase. (663 aa)
Fcgr2bUncharacterized protein. (341 aa)
LOC101968765Uncharacterized protein. (187 aa)
IL1RL1Interleukin 1 receptor like 1. (554 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (226 aa)
CD84CD84 molecule. (301 aa)
PGLYRP2Peptidoglycan recognition protein 2. (522 aa)
SPI1Spi-1 proto-oncogene. (270 aa)
ANXA1Annexin. (346 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (599 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (588 aa)
LyarUncharacterized protein. (190 aa)
PARP14Poly [ADP-ribose] polymerase. (1803 aa)
GFERSulfhydryl oxidase. (206 aa)
IL4RInterleukin 4 receptor. (795 aa)
SAMSN1SAM domain, SH3 domain and nuclear localization signals 1. (373 aa)
OTOP1Otopetrin 1. (583 aa)
Cd55Uncharacterized protein. (432 aa)
LGALS3Galectin. (220 aa)
NMIN-myc and STAT interactor. (308 aa)
Usp18USP domain-containing protein; Belongs to the peptidase C19 family. (354 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (201 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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