STRINGSTRING
CDH23 CDH23 ENSSTOP00000031765 ENSSTOP00000031765 ENSSTOP00000031958 ENSSTOP00000031958 KCNA1 KCNA1 ENSSTOP00000032126 ENSSTOP00000032126 SCN8A SCN8A ENSSTOP00000032440 ENSSTOP00000032440 CDH1 CDH1 CCDC50 CCDC50 COCH COCH LRIG2 LRIG2 KIT KIT GRIN2B GRIN2B ATP6V0A4 ATP6V0A4 KCNQ4 KCNQ4 COL2A1 COL2A1 USH1C USH1C TRPV1 TRPV1 LOC101973790 LOC101973790 GRXCR2 GRXCR2 RAB3A RAB3A SLC12A2 SLC12A2 ATP8B1 ATP8B1 GABRB2 GABRB2 COL11A2 COL11A2 CNTN5 CNTN5 USP53 USP53 CACNB3 CACNB3 TBX1 TBX1 COL11A1 COL11A1 FBXO11 FBXO11 TRPA1 TRPA1 THRB THRB NDUFS4 NDUFS4 TMTC4 TMTC4 GJB6 GJB6 CXCL12 CXCL12 CLRN3 CLRN3 CXCR4 CXCR4 GRM8 GRM8 CRYM CRYM Rest Rest FYN FYN ATP6V1B1 ATP6V1B1 CHRNA5 CHRNA5 NTRK1 NTRK1 HEXB HEXB MYO3B MYO3B KCNK4 KCNK4 HOMER2 HOMER2 TMIE TMIE PDZD7 PDZD7 USH2A USH2A SCARB2 SCARB2 TECTA TECTA SERPINE2 SERPINE2 CLRN2 CLRN2 ITGA2 ITGA2 PGAP1 PGAP1 TJP1 TJP1 UCN UCN SLC26A5 SLC26A5 SLC17A8 SLC17A8 CHD7 CHD7 AXIN1 AXIN1 MYO1A MYO1A TMC2 TMC2 GET1 GET1 GRM7 GRM7 SLC9A3R2 SLC9A3R2 AQP4 AQP4 ESPN ESPN LHFPL5 LHFPL5 CHRNA9 CHRNA9 TECTB TECTB MKKS MKKS CABP2 CABP2 PCDH15 PCDH15 SPNS2 SPNS2 NIPBL NIPBL SLC1A3 SLC1A3 PKHD1L1 PKHD1L1 MYO7B MYO7B PAWR PAWR OTOS OTOS CDKN1B CDKN1B IL18 IL18 FZD4 FZD4 Sptbn4 Sptbn4 CLRN1 CLRN1 POU4F3 POU4F3 TMC1 TMC1 MYO15A MYO15A WHRN WHRN WFS1 WFS1 USH1G USH1G Slc52a3 Slc52a3 Ddit3 Ddit3 DCDC2 DCDC2 Spry2 Spry2 MAP1A MAP1A Myo15b Myo15b HPN HPN PJVK PJVK SOBP SOBP LOC101968119 LOC101968119 TLR4 TLR4 LOXHD1 LOXHD1 CFAP57 CFAP57 SIX1 SIX1 SCN1A SCN1A CDC14A CDC14A Cdkn2d Cdkn2d LOC101957938 LOC101957938 Fam107b Fam107b OTOA OTOA GJC3 GJC3 P2RX2 P2RX2 CHRNA10 CHRNA10 LRIG1 LRIG1 I3N4L5_ICTTR I3N4L5_ICTTR Triobp Triobp KCNQ1 KCNQ1 I3N6R6_ICTTR I3N6R6_ICTTR GJB2 GJB2 CLIC5 CLIC5 SNAI2 SNAI2 OTOGL OTOGL ESPNL ESPNL DRGX DRGX LHFPL4 LHFPL4 GRXCR1 GRXCR1 GRAP GRAP PTPRQ PTPRQ HOXA1 HOXA1 POU4F2 POU4F2 TMEM120A TMEM120A BARHL1 BARHL1 TSPEAR TSPEAR CEMIP CEMIP ASIC3 ASIC3 TH TH I3NDK4_ICTTR I3NDK4_ICTTR TMPRSS3 TMPRSS3 I3NE23_ICTTR I3NE23_ICTTR EPYC EPYC TBX18 TBX18 TPRN TPRN SRRM4 SRRM4 MYH14 MYH14 CEACAM16 CEACAM16 RIPOR2 RIPOR2 GPX1 GPX1 SLC9A3R1 SLC9A3R1 Alg10 Alg10 NAV2 NAV2 MYO7A MYO7A MYO3A MYO3A KCNMA1 KCNMA1 OTOG OTOG ENSSTOP00000025526 ENSSTOP00000025526 COL1A1 COL1A1 EYA4 EYA4 ICAM1 ICAM1 P2RX4 P2RX4 EPS8L2 EPS8L2 ROR1 ROR1 TFAP2A TFAP2A GABRB3 GABRB3 FGFR1 FGFR1 CHRNB2 CHRNB2 Asic2 Asic2 ENSSTOP00000028967 ENSSTOP00000028967 MARVELD2 MARVELD2 LRP2 LRP2 PHF24 PHF24 MYO6 MYO6 TSHZ3 TSHZ3 IGF1 IGF1 ATP2B2 ATP2B2 ENSSTOP00000030319 ENSSTOP00000030319 GABRA5 GABRA5 Hexa Hexa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDH23Cadherin related 23. (3053 aa)
ENSSTOP00000031765Uncharacterized protein. (515 aa)
ENSSTOP00000031958Uncharacterized protein. (80 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (476 aa)
ENSSTOP00000032126Uncharacterized protein. (141 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1975 aa)
ENSSTOP00000032440G_PROTEIN_RECEP_F2_4 domain-containing protein. (318 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (885 aa)
CCDC50Coiled-coil domain containing 50. (308 aa)
COCHCochlin. (550 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1062 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (837 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (629 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
USH1CUSH1 protein network component harmonin. (881 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (840 aa)
LOC101973790Uncharacterized protein. (311 aa)
GRXCR2Glutaredoxin and cysteine rich domain containing 2. (248 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
SLC12A2Solute carrier family 12 member 2. (1108 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
COL11A2Collagen type XI alpha 2 chain. (1689 aa)
CNTN5Contactin 5. (1099 aa)
USP53Ubiquitin specific peptidase 53. (1075 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
TBX1T-box transcription factor 1. (406 aa)
COL11A1Collagen type XI alpha 1 chain. (1721 aa)
FBXO11F-box protein 11. (849 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1. (1044 aa)
THRBThyroid hormone receptor beta. (476 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (175 aa)
TMTC4Transmembrane O-mannosyltransferase targeting cadherins 4. (742 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
CLRN3Clarin 3. (226 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (352 aa)
GRM8Glutamate metabotropic receptor 8. (908 aa)
CRYMCrystallin mu. (314 aa)
RestUncharacterized protein. (328 aa)
FYNTyrosine-protein kinase. (537 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (468 aa)
NTRK1Tyrosine-protein kinase receptor. (799 aa)
HEXBBeta-hexosaminidase. (538 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1304 aa)
KCNK4Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (419 aa)
HOMER2Homer scaffold protein 2. (354 aa)
TMIETransmembrane inner ear. (154 aa)
PDZD7PDZ domain containing 7. (1020 aa)
USH2AUsherin. (5200 aa)
SCARB2Scavenger receptor class B member 2; Belongs to the CD36 family. (428 aa)
TECTATectorin alpha. (2150 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (397 aa)
CLRN2Clarin 2. (232 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1183 aa)
PGAP1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (922 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1738 aa)
UCNUrocortin. (127 aa)
SLC26A5Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (744 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2997 aa)
AXIN1Axin 1. (869 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1042 aa)
TMC2Transmembrane channel-like protein. (868 aa)
GET1Guided entry of tail-anchored proteins factor 1. (174 aa)
GRM7Glutamate metabotropic receptor 7. (629 aa)
SLC9A3R2SLC9A3 regulator 2. (226 aa)
AQP4Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (316 aa)
ESPNEspin. (872 aa)
LHFPL5LHFPL tetraspan subfamily member 5. (231 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (479 aa)
TECTBTectorin beta. (339 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
CABP2Calcium binding protein 2. (221 aa)
PCDH15Protocadherin related 15. (1890 aa)
SPNS2Sphingolipid transporter 2. (494 aa)
NIPBLNipped-B protein. (2803 aa)
SLC1A3Amino acid transporter. (542 aa)
PKHD1L1PKHD1 like 1. (4254 aa)
MYO7BMyosin VIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2098 aa)
PAWRPro-apoptotic WT1 regulator. (340 aa)
OTOSOtospiralin. (87 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
Sptbn4Spectrin beta, non-erythrocytic 4. (2570 aa)
CLRN1Clarin 1. (232 aa)
POU4F3POU domain protein. (338 aa)
TMC1Transmembrane channel-like protein. (705 aa)
MYO15AMyosin XVA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3517 aa)
WHRNWhirlin. (887 aa)
WFS1Wolframin ER transmembrane glycoprotein. (889 aa)
USH1GUSH1 protein network component sans. (421 aa)
Slc52a3Uncharacterized protein. (230 aa)
Ddit3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
DCDC2Doublecortin domain containing 2. (477 aa)
Spry2Uncharacterized protein. (315 aa)
MAP1AMicrotubule associated protein 1A. (3001 aa)
Myo15bSH3 domain-containing protein. (234 aa)
HPNHepsin; Belongs to the peptidase S1 family. (417 aa)
PJVKPejvakin. (348 aa)
SOBPSine oculis binding protein homolog. (762 aa)
LOC101968119SERPIN domain-containing protein; Belongs to the serpin family. (197 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (840 aa)
LOXHD1Lipoxygenase homology domains 1. (2017 aa)
CFAP57Cilia and flagella associated protein 57. (1132 aa)
SIX1SIX homeobox 1. (284 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1998 aa)
CDC14ACell division cycle 14A. (612 aa)
Cdkn2dANK_REP_REGION domain-containing protein. (166 aa)
LOC101957938SERPIN domain-containing protein; Belongs to the serpin family. (377 aa)
Fam107bUncharacterized protein. (153 aa)
OTOAOtoancorin. (1101 aa)
GJC3Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (283 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (455 aa)
CHRNA10Cholinergic receptor nicotinic alpha 10 subunit. (447 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1075 aa)
I3N4L5_ICTTRUncharacterized protein. (120 aa)
TriobpPH domain-containing protein. (564 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (592 aa)
I3N6R6_ICTTRANF_receptor domain-containing protein. (186 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa)
CLIC5Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (252 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
OTOGLOtogelin like. (2284 aa)
ESPNLEspin like. (1003 aa)
DRGXDorsal root ganglia homeobox. (263 aa)
LHFPL4LHFPL tetraspan subfamily member 4. (242 aa)
GRXCR1Glutaredoxin and cysteine rich domain containing 1. (296 aa)
GRAPUncharacterized protein. (157 aa)
PTPRQProtein tyrosine phosphatase receptor type Q. (2237 aa)
HOXA1Homeobox A1. (337 aa)
POU4F2POU domain protein. (410 aa)
TMEM120ATransmembrane protein 120A. (342 aa)
BARHL1BarH like homeobox 1. (327 aa)
TSPEARThrombospondin type laminin G domain and EAR repeats. (667 aa)
CEMIPCell migration inducing hyaluronidase 1. (1365 aa)
ASIC3Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (533 aa)
THTyrosine hydroxylase. (497 aa)
I3NDK4_ICTTRUncharacterized protein. (258 aa)
TMPRSS3Transmembrane serine protease 3; Belongs to the peptidase S1 family. (453 aa)
I3NE23_ICTTRANK_REP_REGION domain-containing protein. (150 aa)
EPYCEpiphycan. (322 aa)
TBX18T-box transcription factor 18. (614 aa)
TPRNTaperin. (656 aa)
SRRM4Serine/arginine repetitive matrix 4. (517 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1807 aa)
CEACAM16Carcinoembryonic antigen related cell adhesion molecule 16. (452 aa)
RIPOR2RHO family interacting cell polarization regulator 2. (1021 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (201 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (358 aa)
Alg10Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase. (474 aa)
NAV2Neuron navigator 2. (2452 aa)
MYO7AMyosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2215 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1595 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1219 aa)
OTOGOtogelin. (2885 aa)
ENSSTOP00000025526Uncharacterized protein. (64 aa)
COL1A1Collagen type I alpha 1 chain. (1268 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (615 aa)
ICAM1Intercellular adhesion molecule 1. (531 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa)
EPS8L2EPS8 like 2. (716 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (956 aa)
TFAP2ATranscription factor AP-2 alpha. (477 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (493 aa)
FGFR1Fibroblast growth factor receptor. (822 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (599 aa)
Asic2Acid sensing ion channel subunit 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (512 aa)
ENSSTOP00000028967Uncharacterized protein. (1864 aa)
MARVELD2MARVEL domain containing 2. (558 aa)
LRP2LDL receptor related protein 2. (4656 aa)
PHF24PHD finger protein 24. (400 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1294 aa)
TSHZ3Teashirt zinc finger homeobox 3. (1089 aa)
IGF1Insulin like growth factor 1. (166 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
ENSSTOP00000030319Uncharacterized protein. (2101 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (545 aa)
HexaBeta-hexosaminidase. (527 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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