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| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa) |
| | TRIM38 | Tripartite motif containing 38. (475 aa) |
| | DHX9 | DExH-box helicase 9. (1328 aa) |
| | TRIML1 | Tripartite motif family like 1. (473 aa) |
| | TRIML2 | Tripartite motif family like 2. (415 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (769 aa) |
| | TRIM14 | Tripartite motif containing 14. (445 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | AR | Androgen receptor. (884 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | TGFBR3 | Transforming growth factor beta receptor 3. (851 aa) |
| | AMH | Anti-Mullerian hormone. (545 aa) |
| | TERF2IP | TERF2 interacting protein. (396 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (951 aa) |
| | TRIM32 | Tripartite motif containing 32. (658 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1014 aa) |
| | TRIM13 | Tripartite motif containing 13. (410 aa) |
| | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (536 aa) |
| | Ins | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (840 aa) |
| | LRRFIP2 | LRR binding FLII interacting protein 2. (437 aa) |
| | MALT1 | MALT1 paracaspase. (747 aa) |
| | Hspa1b | Heat shock protein family A (Hsp70) member 1B. (641 aa) |
| | TRIM15 | Tripartite motif containing 15. (413 aa) |
| | PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa) |
| | TNFRSF11A | TNF receptor superfamily member 11a. (625 aa) |
| | TRIM62 | Tripartite motif containing 62. (475 aa) |
| | CAPN3 | Calpain 3; Belongs to the peptidase C2 family. (821 aa) |
| | CARD14 | Caspase recruitment domain family member 14. (999 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa) |
| | CD84 | CD84 molecule. (301 aa) |
| | ZBTB7A | Zinc finger and BTB domain containing 7A. (414 aa) |
| | Lrrfip1 | Uncharacterized protein. (662 aa) |
| | SPHK1 | Sphingosine kinase 1. (385 aa) |
| | TRAF1 | TNF receptor-associated factor. (415 aa) |
| | CX3CR1 | C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa) |
| | GREM1 | Gremlin. (184 aa) |
| | TLR2 | Toll like receptor 2; Belongs to the Toll-like receptor family. (784 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa) |
| | TRIM6 | Tripartite motif containing 6. (469 aa) |
| | CD40 | CD40 molecule. (284 aa) |
| | RAB7B | RAB7B, member RAS oncogene family. (184 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (397 aa) |
| | I3NG54_ICTTR | Uncharacterized protein. (91 aa) |
| | LOC101961439 | TIR domain-containing protein. (1051 aa) |
| | NLRC4 | NLR family CARD domain containing 4. (841 aa) |
| | CLU | Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (448 aa) |
| | BCL10 | BCL10 immune signaling adaptor. (153 aa) |
| | TRIM27 | Tripartite motif containing 27. (513 aa) |
| | ENSSTOP00000024305 | Uncharacterized protein. (210 aa) |
| | Rps3 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (244 aa) |
| | CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (488 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (715 aa) |
| | ENSSTOP00000025153 | PROTEASOME_ALPHA_1 domain-containing protein. (87 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (450 aa) |
| | RIPK4 | Receptor interacting serine/threonine kinase 4. (803 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (473 aa) |
| | LOC101955567 | Uncharacterized protein. (140 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (531 aa) |
| | IL1RAP | Interleukin 1 receptor accessory protein. (687 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa) |
| | LOC101965602 | Uncharacterized protein. (424 aa) |
| | CARM1 | Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (598 aa) |
| | ROR1 | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (956 aa) |
| | CIB1 | Calcium and integrin binding 1. (191 aa) |
| | APP | Amyloid beta precursor protein. (739 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (492 aa) |
| | CRHR2 | Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (436 aa) |
| | Ptma | Uncharacterized protein. (111 aa) |
| | ENSSTOP00000027615 | Uncharacterized protein. (247 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa) |
| | ENSSTOP00000028911 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (203 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (859 aa) |
| | LOC101974845 | Uncharacterized protein. (112 aa) |
| | LOC101964884 | Uncharacterized protein. (111 aa) |
| | ANKRD42 | Ankyrin repeat domain 42. (523 aa) |
| | LOC101954459 | Uncharacterized protein. (103 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa) |
| | PRKCZ | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (413 aa) |
| | LOC101969154 | Uncharacterized protein. (110 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | Psma6 | Proteasome subunit alpha type. (148 aa) |
| | TRADD | TNFRSF1A associated via death domain. (302 aa) |
| | LOC101961086 | Uncharacterized protein. (109 aa) |
| | NTS | Neurotensin. (170 aa) |
| | NLRP3 | NLR family pyrin domain containing 3. (1035 aa) |
| | TNFSF18 | TNF superfamily member 18. (172 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa) |
| | TIRAP | TIR domain containing adaptor protein. (222 aa) |
| | Prkch | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa) |
| | TRIM25 | Tripartite motif containing 25. (644 aa) |
| | LTF | Lactotransferrin; Belongs to the transferrin family. (709 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa) |
| | EDA2R | Ectodysplasin A2 receptor. (297 aa) |
| | TRIM8 | Tripartite motif containing 8. (551 aa) |
| | MTPN | Myotrophin. (118 aa) |
| | AIM2 | Absent in melanoma 2. (349 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (799 aa) |
| | ERC1 | ELKS/RAB6-interacting/CAST family member 1. (1120 aa) |
| | Card11 | Uncharacterized protein. (1152 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa) |
| | IRAK3 | Interleukin 1 receptor associated kinase 3. (607 aa) |
| | STAT3 | Signal transducer and activator of transcription. (748 aa) |
| | RNF25 | Ring finger protein 25. (459 aa) |
| | DDRGK1 | DDRGK domain containing 1. (306 aa) |
| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (259 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa) |
| | MTDH | Metadherin. (581 aa) |
| | TRIM21 | Tripartite motif containing 21. (477 aa) |
| | IL18R1 | Interleukin 18 receptor 1. (539 aa) |
| | RHEBL1 | RHEB like 1. (183 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (843 aa) |
| | TFRC | Transferrin receptor. (760 aa) |
| | LAMTOR5 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa) |
| | DHX33 | DEAH-box helicase 33. (701 aa) |
| | PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa) |
| | PRDX3 | Peroxiredoxin 3. (257 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily. (491 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (200 aa) |
| | Rnf31 | Uncharacterized protein. (1071 aa) |
| | I3LZW4_ICTTR | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (129 aa) |
| | LOC101954381 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (176 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (665 aa) |
| | ITGB2 | Integrin beta. (769 aa) |
| | EDA | Ectodysplasin A; Belongs to the tumor necrosis factor family. (391 aa) |
| | FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) |
| | EP300 | E1A binding protein p300. (2423 aa) |
| | I3LX72_ICTTR | PH domain-containing protein. (285 aa) |
| | ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2. (869 aa) |
| | CTH | Cystathionine gamma-lyase. (405 aa) |
| | TRAPPC9 | Trafficking protein particle complex 9. (1138 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (818 aa) |
| | FLOT1 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa) |
| | TRIM37 | Tripartite motif containing 37. (965 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | SLCO3A1 | Solute carrier organic anion transporter family member. (639 aa) |
| | Hspa1a | Uncharacterized protein; Belongs to the heat shock protein 70 family. (641 aa) |
| | PYCARD | PYD and CARD domain containing. (194 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (538 aa) |
| | IRAK2 | Interleukin 1 receptor associated kinase 2. (616 aa) |
| | CARD9 | Caspase recruitment domain family member 9. (537 aa) |
| | TRIM68 | Tripartite motif containing 68. (485 aa) |
| | I3MMH2_ICTTR | B box-type domain-containing protein. (150 aa) |
