(13 nodes) Positive regulation of histone H3-K9 methylation network (Ictidomys tridecemlineatus)

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Your Input:
	PRDM12	PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (382 aa)
	Brca1	Uncharacterized protein. (353 aa)
	LMNA	Lamin A/C; Belongs to the intermediate filament family. (665 aa)
	DMRTC2	DMRT like family C2. (371 aa)
	MYB	MYB proto-oncogene, transcription factor. (753 aa)
	JARID2	Jumonji and AT-rich interaction domain containing 2. (1226 aa)
	SUV39H1	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (412 aa)
	GFI1B	Growth factor independent 1B transcriptional repressor. (360 aa)
	SIRT1	Sirtuin 1. (602 aa)
	RIF1	Replication timing regulatory factor 1. (2480 aa)
	Znf304	Zinc finger protein 304. (616 aa)
	MECP2	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (486 aa)
	ENSSTOP00000027930	Uncharacterized protein. (173 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Brca1	ENSSTOP00000027930	ENSSTOP00000000449	ENSSTOP00000027930	Uncharacterized protein.	Uncharacterized protein.	0.899
Brca1	RIF1	ENSSTOP00000000449	ENSSTOP00000015314	Uncharacterized protein.	Replication timing regulatory factor 1.	0.666
ENSSTOP00000027930	Brca1	ENSSTOP00000027930	ENSSTOP00000000449	Uncharacterized protein.	Uncharacterized protein.	0.899
ENSSTOP00000027930	RIF1	ENSSTOP00000027930	ENSSTOP00000015314	Uncharacterized protein.	Replication timing regulatory factor 1.	0.666
JARID2	SIRT1	ENSSTOP00000010493	ENSSTOP00000015219	Jumonji and AT-rich interaction domain containing 2.	Sirtuin 1.	0.467
JARID2	SUV39H1	ENSSTOP00000010493	ENSSTOP00000013735	Jumonji and AT-rich interaction domain containing 2.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.	0.467
MECP2	SIRT1	ENSSTOP00000026241	ENSSTOP00000015219	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	Sirtuin 1.	0.438
MECP2	SUV39H1	ENSSTOP00000026241	ENSSTOP00000013735	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.	0.728
PRDM12	SUV39H1	ENSSTOP00000005349	ENSSTOP00000013735	PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.	0.676
RIF1	Brca1	ENSSTOP00000015314	ENSSTOP00000000449	Replication timing regulatory factor 1.	Uncharacterized protein.	0.666
RIF1	ENSSTOP00000027930	ENSSTOP00000015314	ENSSTOP00000027930	Replication timing regulatory factor 1.	Uncharacterized protein.	0.666
SIRT1	JARID2	ENSSTOP00000015219	ENSSTOP00000010493	Sirtuin 1.	Jumonji and AT-rich interaction domain containing 2.	0.467
SIRT1	MECP2	ENSSTOP00000015219	ENSSTOP00000026241	Sirtuin 1.	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	0.438
SIRT1	SUV39H1	ENSSTOP00000015219	ENSSTOP00000013735	Sirtuin 1.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.	0.937
SUV39H1	JARID2	ENSSTOP00000013735	ENSSTOP00000010493	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.	Jumonji and AT-rich interaction domain containing 2.	0.467
SUV39H1	MECP2	ENSSTOP00000013735	ENSSTOP00000026241	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	0.728
SUV39H1	PRDM12	ENSSTOP00000013735	ENSSTOP00000005349	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.	PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily.	0.676
SUV39H1	SIRT1	ENSSTOP00000013735	ENSSTOP00000015219	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.	Sirtuin 1.	0.937