STRINGSTRING
CARM1 CARM1 CPS1 CPS1 MMP19 MMP19 AQP8 AQP8 RAPGEF3 RAPGEF3 CYP27B1 CYP27B1 PIK3CG PIK3CG CYP1B1 CYP1B1 SLC5A5 SLC5A5 HMGCS2 HMGCS2 PAX4 PAX4 KDM1A KDM1A Ahr Ahr FOSL1 FOSL1 HCN2 HCN2 FDX1 FDX1 SLC8A3 SLC8A3 Pkd2 Pkd2 TYR TYR WNT10B WNT10B INPP5K INPP5K NDUFS4 NDUFS4 PER1 PER1 CREM CREM I3M6L1_ICTTR I3M6L1_ICTTR Birc2 Birc2 AKAP9 AKAP9 STC1 STC1 AGXT AGXT NOX4 NOX4 CITED1 CITED1 ALDH3A1 ALDH3A1 STAT1 STAT1 AREG AREG DUOX2 DUOX2 DUOX1 DUOX1 HCN1 HCN1 HCN3 HCN3 CRHBP CRHBP PLAT PLAT APEX1 APEX1 MAT2A MAT2A SLC26A3 SLC26A3 RAP1B RAP1B Rplp0 Rplp0 CDO1 CDO1 AANAT AANAT AQP9 AQP9 DGKQ DGKQ BCKDHB BCKDHB PCK1 PCK1 LOC101967926 LOC101967926 REN REN Aqp1 Aqp1 ADIPOQ ADIPOQ PFKFB1 PFKFB1 AKAP7 AKAP7 Kcne1 Kcne1 RAP1A RAP1A WT1 WT1 PDE4D PDE4D IGFBP5 IGFBP5 GATA6 GATA6 BSG BSG SLC6A3 SLC6A3 VGF VGF INHBB INHBB KCNQ1 KCNQ1 AKAP6 AKAP6 PNPT1 PNPT1 LOC101967640 LOC101967640 GATA1 GATA1 DMTN DMTN JUN JUN FOSB FOSB ITPR2 ITPR2 HCN4 HCN4 ENSSTOP00000025025 ENSSTOP00000025025 ITPR3 ITPR3 COL1A1 COL1A1 PIK3R1 PIK3R1 PDE2A PDE2A ITPR1 ITPR1 ASS1 ASS1 SREBF1 SREBF1 Akap7 Akap7 ENSSTOP00000030003 ENSSTOP00000030003 PPARGC1B PPARGC1B EZR EZR EEF2K EEF2K PKLR PKLR PTK2B PTK2B RAPGEF2 RAPGEF2 SLC26A6 SLC26A6 LOC101978336 LOC101978336 CNGA3 CNGA3 RAPGEF1 RAPGEF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (598 aa)
CPS1Carbamoyl-phosphate synthase 1. (1500 aa)
MMP19Matrix metallopeptidase 19. (539 aa)
AQP8Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (246 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (898 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (504 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1071 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
SLC5A5Solute carrier family 5 member 5; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (632 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (507 aa)
PAX4Paired box 4. (350 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (755 aa)
AhrUncharacterized protein. (848 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (275 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (838 aa)
FDX1Ferredoxin 1. (184 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (929 aa)
Pkd2EF-hand domain-containing protein. (892 aa)
TYRTyrosinase. (530 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (510 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (175 aa)
PER1Period circadian regulator 1. (1294 aa)
CREMcAMP responsive element modulator. (360 aa)
I3M6L1_ICTTRABC transmembrane type-1 domain-containing protein. (528 aa)
Birc2Uncharacterized protein. (611 aa)
AKAP9A-kinase anchoring protein 9. (3713 aa)
STC1Stanniocalcin 1. (247 aa)
AGXTSerine--pyruvate aminotransferase. (414 aa)
NOX4NADPH oxidase 4. (578 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (195 aa)
ALDH3A1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (453 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
AREGAmphiregulin. (252 aa)
DUOX2Dual oxidase 2. (1517 aa)
DUOX1Dual oxidase 1. (1551 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (832 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (780 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (560 aa)
APEX1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa)
MAT2AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (395 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (758 aa)
RAP1BRAP1B, member of RAS oncogene family. (159 aa)
Rplp060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (317 aa)
CDO1Cysteine dioxygenase. (200 aa)
AANATAralkylamine N-acetyltransferase. (212 aa)
AQP9Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
DGKQDiacylglycerol kinase. (924 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (326 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
LOC101967926Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (124 aa)
RENRenin; Belongs to the peptidase A1 family. (401 aa)
Aqp1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (471 aa)
AKAP7A-kinase anchoring protein 7. (344 aa)
Kcne1Uncharacterized protein. (129 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
WT1WT1 transcription factor. (523 aa)
PDE4DPhosphodiesterase 4D; Belongs to the cyclic nucleotide phosphodiesterase family. (808 aa)
IGFBP5Insulin like growth factor binding protein 5. (271 aa)
GATA6GATA binding protein 6. (593 aa)
BSGBasigin (Ok blood group). (389 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (587 aa)
VGFVGF nerve growth factor inducible. (615 aa)
INHBBInhibin subunit beta B. (336 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (592 aa)
AKAP6A-kinase anchoring protein 6. (2318 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (784 aa)
LOC101967640Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (125 aa)
GATA1GATA binding protein 1. (413 aa)
DMTNDematin actin binding protein. (405 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1207 aa)
ENSSTOP0000002502560S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (286 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
COL1A1Collagen type I alpha 1 chain. (1268 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PDE2APhosphodiesterase. (941 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2748 aa)
ASS1Argininosuccinate synthase 1. (412 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1152 aa)
Akap7AKAP7_RIRII_bdg domain-containing protein. (81 aa)
ENSSTOP00000030003Uncharacterized protein. (546 aa)
PPARGC1BPPARG coactivator 1 beta. (1033 aa)
EZREzrin. (604 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (565 aa)
PTK2BProtein tyrosine kinase 2 beta. (968 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1650 aa)
SLC26A6Solute carrier family 26 member 6. (740 aa)
LOC10197833660S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (300 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (688 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1261 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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