STRINGSTRING
ACVR1 ACVR1 EDN1 EDN1 GATA3 GATA3 BMP4 BMP4 TGFB2 TGFB2 BMPR2 BMPR2 BMP5 BMP5 ADGRF4 ADGRF4 NKX2-5 NKX2-5 TBX1 TBX1 EYA1 EYA1 ECE1 ECE1 ADGRF5 ADGRF5 BMP7 BMP7 ISL1 ISL1 TGFBR1 TGFBR1 PLXNA2 PLXNA2 BMPR1A BMPR1A HOXA2 HOXA2 SIX1 SIX1 SIX4 SIX4 HES1 HES1 EDNRA EDNRA NKX2-6 NKX2-6 SMARCA4 SMARCA4 NKX3-1 NKX3-1 FOLR1 FOLR1 FGF8 FGF8 Ripply3 Ripply3 PTCH1 PTCH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
EDN1Endothelin 1. (202 aa)
GATA3GATA binding protein 3. (444 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
ADGRF4Adhesion G protein-coupled receptor F4; Belongs to the G-protein coupled receptor 2 family. (662 aa)
NKX2-5NK2 homeobox 5. (321 aa)
TBX1T-box transcription factor 1. (406 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
ECE1Endothelin converting enzyme 1. (727 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1382 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
ISL1ISL LIM homeobox 1. (349 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (489 aa)
PLXNA2Plexin A2. (1795 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
HOXA2Homeobox A2. (374 aa)
SIX1SIX homeobox 1. (284 aa)
SIX4SIX homeobox 4. (781 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
NKX2-6NK2 homeobox 6. (282 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1646 aa)
NKX3-1NK3 homeobox 1. (144 aa)
FOLR1Folate receptor alpha. (255 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
Ripply3Uncharacterized protein. (177 aa)
PTCH1Patched 1. (1450 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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