STRINGSTRING
STAT3 STAT3 RXFP4 RXFP4 INSR INSR CFAP20 CFAP20 NR4A3 NR4A3 NMU NMU NPSR1 NPSR1 UCN UCN IFT88 IFT88 GHSR GHSR EIF2AK4 EIF2AK4 INSL5 INSL5 AGRP AGRP MC3R MC3R DRD1 DRD1 HTR1A HTR1A Ins Ins RETN RETN LEPR LEPR MC4R MC4R Ankrd30a Ankrd30a CCK CCK GPR171 GPR171 NAPEPLD NAPEPLD TRH TRH CNR1 CNR1 DGAT1 DGAT1 GHRL GHRL I3NH06_ICTTR I3NH06_ICTTR QRFP QRFP TTC21B TTC21B ENSSTOP00000025615 ENSSTOP00000025615 Crhr1 Crhr1 CRHR2 CRHR2 SGIP1 SGIP1 ESR2 ESR2 LOC101962180 LOC101962180 SLC24A4 SLC24A4 MTOR MTOR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STAT3Signal transducer and activator of transcription. (748 aa)
RXFP4Relaxin family peptide/INSL5 receptor 4. (374 aa)
INSRTyrosine-protein kinase receptor. (1359 aa)
CFAP20Cilia and flagella associated protein 20. (276 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (630 aa)
NMUNeuromedin U. (170 aa)
NPSR1Neuropeptide S receptor 1. (372 aa)
UCNUrocortin. (127 aa)
IFT88Intraflagellar transport 88. (825 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1631 aa)
INSL5Insulin like 5. (135 aa)
AGRPAgouti related neuropeptide. (132 aa)
MC3RMelanocortin 3 receptor. (322 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (445 aa)
HTR1A5-hydroxytryptamine receptor 1A. (423 aa)
InsInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
RETNResistin. (109 aa)
LEPRLeptin receptor. (1148 aa)
MC4RMelanocortin 4 receptor. (333 aa)
Ankrd30aANK_REP_REGION domain-containing protein. (1545 aa)
CCKCholecystokinin. (115 aa)
GPR171G protein-coupled receptor 171; Belongs to the G-protein coupled receptor 1 family. (319 aa)
NAPEPLDN-acyl phosphatidylethanolamine phospholipase D. (400 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (240 aa)
CNR1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (473 aa)
DGAT1O-acyltransferase. (500 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
I3NH06_ICTTRMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (314 aa)
QRFPPyroglutamylated RFamide peptide. (108 aa)
TTC21BTetratricopeptide repeat domain 21B. (1316 aa)
ENSSTOP00000025615DUF3496 domain-containing protein. (484 aa)
Crhr1Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (416 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (436 aa)
SGIP1SH3 domain GRB2 like endophilin interacting protein 1. (846 aa)
ESR2Estrogen receptor 2. (525 aa)
LOC101962180Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (314 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (615 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2577 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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