STRINGSTRING
MAP2K1 MAP2K1 PLCD3 PLCD3 SOCS3 SOCS3 NFE2 NFE2 LLGL2 LLGL2 PKD1 PKD1 FBXW8 FBXW8 CCN1 CCN1 VASH1 VASH1 VASH2 VASH2 I3N0W3_ICTTR I3N0W3_ICTTR OVOL2 OVOL2 HEY2 HEY2 SYDE1 SYDE1 HS6ST1 HS6ST1 HES1 HES1 NSDHL NSDHL HEY1 HEY1 NCOA6 NCOA6 PLG PLG Apela Apela RBPJ RBPJ Arid1a Arid1a TMED2 TMED2 AKT1 AKT1 JUNB JUNB SPINT1 SPINT1 PLCD1 PLCD1 GGNBP2 GGNBP2 FOSL1 FOSL1 Pkd2 Pkd2 NOTCH2 NOTCH2 WNT2 WNT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
PLCD3Phosphoinositide phospholipase C. (782 aa)
SOCS3Suppressor of cytokine signaling 3. (227 aa)
NFE2Nuclear factor, erythroid 2. (374 aa)
LLGL2LLGL scribble cell polarity complex component 2. (1024 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4252 aa)
FBXW8F-box and WD repeat domain containing 8. (492 aa)
CCN1Cellular communication network factor 1. (381 aa)
VASH1Vasohibin 1. (366 aa)
VASH2Vasohibin 2. (355 aa)
I3N0W3_ICTTRBAF250_C domain-containing protein. (135 aa)
OVOL2Ovo like zinc finger 2. (276 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
SYDE1Synapse defective Rho GTPase homolog 1. (737 aa)
HS6ST1Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (358 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
NSDHLNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (361 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
NCOA6Nuclear receptor coactivator 6. (2064 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (794 aa)
ApelaUncharacterized protein. (54 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (522 aa)
Arid1aARID domain-containing protein. (1014 aa)
TMED2Transmembrane p24 trafficking protein 2. (128 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (510 aa)
PLCD1Phosphoinositide phospholipase C. (756 aa)
GGNBP2Gametogenetin binding protein 2. (738 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (275 aa)
Pkd2EF-hand domain-containing protein. (892 aa)
NOTCH2Notch receptor 2. (2364 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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