STRINGSTRING
NLGN2 NLGN2 CAMK1 CAMK1 Cux2 Cux2 PAFAH1B1 PAFAH1B1 DBNL DBNL TSC2 TSC2 OPA1 OPA1 DNM1L DNM1L RELN RELN ACTR3 ACTR3 STAU2 STAU2 ITPKA ITPKA CAPRIN1 CAPRIN1 EEF2K EEF2K ZMYND8 ZMYND8 RAC1 RAC1 CASK CASK KALRN KALRN MFN1 MFN1 CREBBP CREBBP CAPRIN2 CAPRIN2 FMR1 FMR1 DHX36 DHX36 MFN2 MFN2 ACTR2 ACTR2 Cfl1 Cfl1 DBN1 DBN1 SHANK1 SHANK1 NLGN1 NLGN1 ENSSTOP00000027288 ENSSTOP00000027288 LOC101974667 LOC101974667 PAK3 PAK3 HNRNPK HNRNPK EPHB2 EPHB2 MECP2 MECP2 ENSSTOP00000025781 ENSSTOP00000025781 PSEN1 PSEN1 MAPKAPK5 MAPKAPK5 ENSSTOP00000024231 ENSSTOP00000024231 AFDN AFDN LRP8 LRP8 Ppp1r9a Ppp1r9a DLG5 DLG5 PBRM1 PBRM1 LPAR1 LPAR1 ITSN1 ITSN1 CPEB3 CPEB3 I3N6Q6_ICTTR I3N6Q6_ICTTR Bhlhb9 Bhlhb9 SHANK3 SHANK3 C21orf91 C21orf91 NEURL1 NEURL1 FOXO6 FOXO6 IL2 IL2 NLGN3 NLGN3 CDKL5 CDKL5 PALM PALM LLPH LLPH MTOR MTOR BAIAP2 BAIAP2 CAMK2B CAMK2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NLGN2Neuroligin 2. (744 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (370 aa)
Cux2Uncharacterized protein. (61 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (411 aa)
DBNLDrebrin like. (433 aa)
TSC2TSC complex subunit 2. (1745 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (947 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
RELNReelin. (3416 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (418 aa)
STAU2Staufen double-stranded RNA binding protein 2. (607 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (460 aa)
CAPRIN1Cell cycle associated protein 1. (710 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
ZMYND8Zinc finger MYND-type containing 8. (1187 aa)
RAC1Rac family small GTPase 1. (211 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (930 aa)
KALRNKalirin RhoGEF kinase. (2951 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (741 aa)
CREBBPCREB binding protein. (2410 aa)
CAPRIN2Caprin family member 2. (1205 aa)
FMR1Fragile X mental retardation 1. (631 aa)
DHX36DEAH-box helicase 36. (1000 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
Cfl1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (203 aa)
DBN1Drebrin 1. (679 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (1514 aa)
NLGN1Neuroligin 1. (843 aa)
ENSSTOP00000027288PHD-type domain-containing protein. (197 aa)
LOC101974667Protein kinase domain-containing protein. (692 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
HNRNPKHeterogeneous nuclear ribonucleoprotein K. (464 aa)
EPHB2EPH receptor B2. (978 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (486 aa)
ENSSTOP00000025781Guanylate kinase-like domain-containing protein. (243 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
MAPKAPK5MAPK activated protein kinase 5. (472 aa)
ENSSTOP00000024231Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (276 aa)
AFDNAfadin, adherens junction formation factor. (1801 aa)
LRP8LDL receptor related protein 8. (940 aa)
Ppp1r9aUncharacterized protein. (446 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1920 aa)
PBRM1Polybromo 1. (1710 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
ITSN1Intersectin 1. (1655 aa)
CPEB3Cytoplasmic polyadenylation element binding protein 3. (697 aa)
I3N6Q6_ICTTRADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (160 aa)
Bhlhb9Arm_2 domain-containing protein. (545 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1645 aa)
C21orf91Chromosome 21 open reading frame 91. (297 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
FOXO6Forkhead box O6. (370 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
NLGN3Neuroligin 3. (848 aa)
CDKL5Cyclin dependent kinase like 5. (960 aa)
PALMParalemmin. (393 aa)
LLPHLLP homolog, long-term synaptic facilitation factor. (127 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2577 aa)
BAIAP2BAI1 associated protein 2. (535 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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