(28 nodes) Positive regulation of cartilage development network (Ictidomys tridecemlineatus)

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Known Interactions

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Predicted Interactions

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Your Input:
	MDK	Midkine. (143 aa)
	PKDCC	Protein kinase domain containing, cytoplasmic. (294 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
	ZBTB16	Zinc finger and BTB domain containing 16. (673 aa)
	THRB	Thyroid hormone receptor beta. (476 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	BMP10	Bone morphogenetic protein 10. (422 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	SOX6	SRY-box transcription factor 6. (855 aa)
	LOXL2	Lysyl oxidase like 2. (776 aa)
	BMP1	Metalloendopeptidase. (934 aa)
	ZNF219	Zinc finger protein 219. (753 aa)
	SMAD7	Mothers against decapentaplegic homolog. (426 aa)
	HOXA11	Homeobox A11. (315 aa)
	CCN1	Cellular communication network factor 1. (381 aa)
	BMP6	Bone morphogenetic protein 6. (507 aa)
	GDF6	Growth differentiation factor 6. (460 aa)
	BMP2	Bone morphogenetic protein 2. (395 aa)
	Mustn1	Uncharacterized protein. (82 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
	SOX9	SRY-box transcription factor 9. (509 aa)
	FGF18	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	GDF2	Growth differentiation factor 2. (429 aa)
	GDF5	Growth differentiation factor 5. (495 aa)
	GLI3	GLI family zinc finger 3. (1582 aa)
	SOX5	SRY-box transcription factor 5. (763 aa)
	RUNX2	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (520 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP1	BMP2	ENSSTOP00000014783	ENSSTOP00000018746	Metalloendopeptidase.	Bone morphogenetic protein 2.	0.587
BMP1	BMP4	ENSSTOP00000014783	ENSSTOP00000001023	Metalloendopeptidase.	Bone morphogenetic protein 4.	0.452
BMP10	BMP2	ENSSTOP00000009290	ENSSTOP00000018746	Bone morphogenetic protein 10.	Bone morphogenetic protein 2.	0.509
BMP10	BMP4	ENSSTOP00000009290	ENSSTOP00000001023	Bone morphogenetic protein 10.	Bone morphogenetic protein 4.	0.480
BMP10	BMP6	ENSSTOP00000009290	ENSSTOP00000017540	Bone morphogenetic protein 10.	Bone morphogenetic protein 6.	0.432
BMP10	BMPR2	ENSSTOP00000009290	ENSSTOP00000002111	Bone morphogenetic protein 10.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.994
BMP10	GDF2	ENSSTOP00000009290	ENSSTOP00000022676	Bone morphogenetic protein 10.	Growth differentiation factor 2.	0.771
BMP10	GDF5	ENSSTOP00000009290	ENSSTOP00000022883	Bone morphogenetic protein 10.	Growth differentiation factor 5.	0.479
BMP10	GDF6	ENSSTOP00000009290	ENSSTOP00000018656	Bone morphogenetic protein 10.	Growth differentiation factor 6.	0.472
BMP10	SMAD1	ENSSTOP00000009290	ENSSTOP00000009717	Bone morphogenetic protein 10.	Mothers against decapentaplegic homolog.	0.414
BMP2	BMP1	ENSSTOP00000018746	ENSSTOP00000014783	Bone morphogenetic protein 2.	Metalloendopeptidase.	0.587
BMP2	BMP10	ENSSTOP00000018746	ENSSTOP00000009290	Bone morphogenetic protein 2.	Bone morphogenetic protein 10.	0.509
BMP2	BMP4	ENSSTOP00000018746	ENSSTOP00000001023	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.887
BMP2	BMP6	ENSSTOP00000018746	ENSSTOP00000017540	Bone morphogenetic protein 2.	Bone morphogenetic protein 6.	0.919
BMP2	BMPR2	ENSSTOP00000018746	ENSSTOP00000002111	Bone morphogenetic protein 2.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.984
BMP2	FGF18	ENSSTOP00000018746	ENSSTOP00000022441	Bone morphogenetic protein 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.425
BMP2	GDF2	ENSSTOP00000018746	ENSSTOP00000022676	Bone morphogenetic protein 2.	Growth differentiation factor 2.	0.480
BMP2	GDF5	ENSSTOP00000018746	ENSSTOP00000022883	Bone morphogenetic protein 2.	Growth differentiation factor 5.	0.729
BMP2	GDF6	ENSSTOP00000018746	ENSSTOP00000018656	Bone morphogenetic protein 2.	Growth differentiation factor 6.	0.579
BMP2	RUNX2	ENSSTOP00000018746	ENSSTOP00000029414	Bone morphogenetic protein 2.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.736