(11 nodes) Cardiac neural crest cell development involved in outflow tract morphogenesis network (Ictidomys tridecemlineatus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Pitx2	Homeobox protein. (325 aa)
	EDN1	Endothelin 1. (202 aa)
	Cdc42	Uncharacterized protein. (191 aa)
	I3N4S4_ICTTR	Uncharacterized protein. (162 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	HAND2	Heart and neural crest derivatives expressed 2. (217 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	DICER1	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1904 aa)
	FOLR1	Folate receptor alpha. (255 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	LOC101966144	Uncharacterized protein. (147 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDN1	EDNRA	ENSSTOP00000000496	ENSSTOP00000021182	Endothelin 1.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.995
EDN1	HAND2	ENSSTOP00000000496	ENSSTOP00000020619	Endothelin 1.	Heart and neural crest derivatives expressed 2.	0.533
EDNRA	EDN1	ENSSTOP00000021182	ENSSTOP00000000496	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.995
HAND2	EDN1	ENSSTOP00000020619	ENSSTOP00000000496	Heart and neural crest derivatives expressed 2.	Endothelin 1.	0.533
HES1	JAG1	ENSSTOP00000020051	ENSSTOP00000026569	Hes family bHLH transcription factor 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.540
JAG1	HES1	ENSSTOP00000026569	ENSSTOP00000020051	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hes family bHLH transcription factor 1.	0.540