STRINGSTRING
ABCB6 ABCB6 MAPK8 MAPK8 MT2A MT2A MAPK1 MAPK1 CHUK CHUK FOXA2 FOXA2 CYP1A2 CYP1A2 MT3 MT3 JUN JUN Sumo1 Sumo1 MAPK9 MAPK9 ENSSTOP00000029812 ENSSTOP00000029812 AKT1 AKT1 HSF1 HSF1 ATP7A ATP7A FOS FOS GSN GSN MT4 MT4 MMP9 MMP9 NCF1 NCF1 EGFR EGFR HMOX1 HMOX1 CYBB CYBB HESX1 HESX1 MAPK3 MAPK3 OGG1 OGG1 DAXX DAXX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABCB6ATP binding cassette subfamily B member 6 (Langereis blood group). (843 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
MT2AMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
MAPK1Mitogen-activated protein kinase. (331 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (769 aa)
FOXA2Forkhead box A2. (463 aa)
CYP1A2Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (515 aa)
MT3Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (68 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
Sumo1Small ubiquitin-related modifier 1; Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post- translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for insta [...] (101 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
ENSSTOP00000029812Small ubiquitin-related modifier. (112 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
HSF1Heat shock transcription factor 1. (545 aa)
ATP7AATPase copper transporting alpha. (1495 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
GSNGelsolin. (748 aa)
MT4Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (62 aa)
MMP9Matrix metallopeptidase 9. (667 aa)
NCF1Neutrophil cytosolic factor 1. (405 aa)
EGFRReceptor protein-tyrosine kinase. (1192 aa)
HMOX1Heme oxygenase 1. (288 aa)
CYBBCytochrome b-245 beta chain. (549 aa)
HESX1HESX homeobox 1. (184 aa)
MAPK3Mitogen-activated protein kinase. (361 aa)
OGG18-oxoguanine DNA glycosylase. (344 aa)
DAXXDeath domain associated protein. (740 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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