STRINGSTRING
BMP4 BMP4 Pkd2 Pkd2 PAX2 PAX2 BMP7 BMP7 AMER1 AMER1 OSR1 OSR1 SHH SHH SMAD4 SMAD4 WT1 WT1 SIX1 SIX1 SIX4 SIX4 SIX2 SIX2 PDGFRB PDGFRB TCF21 TCF21
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP4Bone morphogenetic protein 4. (409 aa)
Pkd2EF-hand domain-containing protein. (892 aa)
PAX2Paired box 2. (417 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
AMER1APC membrane recruitment protein 1. (1136 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
SHHSonic hedgehog signaling molecule. (370 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
WT1WT1 transcription factor. (523 aa)
SIX1SIX homeobox 1. (284 aa)
SIX4SIX homeobox 4. (781 aa)
SIX2SIX homeobox 2. (296 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1112 aa)
TCF21Transcription factor 21. (179 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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