(9 nodes) Ureter morphogenesis network (Ictidomys tridecemlineatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP4	Bone morphogenetic protein 4. (409 aa)
	MECOM	MDS1 and EVI1 complex locus. (1051 aa)
	EMX2	Empty spiracles homeobox 2. (253 aa)
	SOX9	SRY-box transcription factor 9. (509 aa)
	LHX1	LIM homeobox 1. (406 aa)
	LZTS2	Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (677 aa)
	PAX2	Paired box 2. (417 aa)
	SOX8	SRY-box transcription factor 8. (466 aa)
	GATA3	GATA binding protein 3. (444 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EMX2	PAX2	ENSSTOP00000027188	ENSSTOP00000010388	Empty spiracles homeobox 2.	Paired box 2.	0.410
GATA3	LHX1	ENSSTOP00000000959	ENSSTOP00000017354	GATA binding protein 3.	LIM homeobox 1.	0.422
LHX1	GATA3	ENSSTOP00000017354	ENSSTOP00000000959	LIM homeobox 1.	GATA binding protein 3.	0.422
LHX1	PAX2	ENSSTOP00000017354	ENSSTOP00000010388	LIM homeobox 1.	Paired box 2.	0.537
PAX2	EMX2	ENSSTOP00000010388	ENSSTOP00000027188	Paired box 2.	Empty spiracles homeobox 2.	0.410
PAX2	LHX1	ENSSTOP00000010388	ENSSTOP00000017354	Paired box 2.	LIM homeobox 1.	0.537
PAX2	SOX9	ENSSTOP00000010388	ENSSTOP00000021123	Paired box 2.	SRY-box transcription factor 9.	0.408
SOX9	PAX2	ENSSTOP00000021123	ENSSTOP00000010388	SRY-box transcription factor 9.	Paired box 2.	0.408