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| | I3NCK5_ICTTR | CARD domain-containing protein. (102 aa) |
| | LOC101968601 | Uncharacterized protein. (80 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (804 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1386 aa) |
| | DAPK3 | Death associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa) |
| | ENSSTOP00000032292 | Miro domain-containing protein. (101 aa) |
| | IVNS1ABP | Influenza virus NS1A binding protein. (642 aa) |
| | ENSSTOP00000032126 | Uncharacterized protein. (141 aa) |
| | VDR | Vitamin D receptor. (423 aa) |
| | Tmbim7p | Uncharacterized protein; Belongs to the BI1 family. (302 aa) |
| | ZNF385B | Zinc finger protein 385B. (486 aa) |
| | RPS27L | 40S ribosomal protein S27. (109 aa) |
| | PPM1F | Protein phosphatase, Mg2+/Mn2+ dependent 1F. (452 aa) |
| | ENSSTOP00000031310 | Uncharacterized protein; Belongs to the peptidase C14A family. (233 aa) |
| | TNFSF12 | TNF superfamily member 12; Belongs to the tumor necrosis factor family. (249 aa) |
| | IL7 | Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (159 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | NGF | Nerve growth factor; Belongs to the NGF-beta family. (305 aa) |
| | BCL2L2 | BCL2 like 2. (193 aa) |
| | HTRA2 | HtrA serine peptidase 2. (458 aa) |
| | Inhba | TGF_BETA_2 domain-containing protein. (133 aa) |
| | IGF1 | Insulin like growth factor 1. (166 aa) |
| | ESR2 | Estrogen receptor 2. (525 aa) |
| | VDAC2 | Voltage dependent anion channel 2. (294 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (208 aa) |
| | PDK1 | Protein-serine/threonine kinase. (436 aa) |
| | ENSSTOP00000029171 | Uncharacterized protein. (73 aa) |
| | ENSSTOP00000029159 | WRNPLPNID domain-containing protein. (83 aa) |
| | MFF | Mitochondrial fission factor. (316 aa) |
| | FHIT | Bis(5'-adenosyl)-triphosphatase. (151 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa) |
| | MOAP1 | Modulator of apoptosis 1. (350 aa) |
| | ENSSTOP00000027930 | Uncharacterized protein. (173 aa) |
| | PDK2 | Protein-serine/threonine kinase. (407 aa) |
| | TNFRSF12A | TNF receptor superfamily member 12A. (129 aa) |
| | STK3 | Serine/threonine kinase 3. (491 aa) |
| | ENSSTOP00000027321 | Uncharacterized protein. (207 aa) |
| | CDIP1 | Cell death inducing p53 target 1. (240 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2748 aa) |
| | NF1 | Neurofibromin 1. (2473 aa) |
| | ENSSTOP00000027050 | Thioredoxin domain-containing protein. (188 aa) |
| | UBE2K | Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa) |
| | ENSSTOP00000026714 | HIT domain-containing protein. (122 aa) |
| | P2RX4 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa) |
| | HMOX1 | Heme oxygenase 1. (288 aa) |
| | ENSSTOP00000026508 | BH4_2 domain-containing protein. (224 aa) |
| | ENSSTOP00000026381 | Uncharacterized protein. (87 aa) |
| | RHOT1 | Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (704 aa) |
| | Bex3 | Uncharacterized protein. (102 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | LOC101962169 | Uncharacterized protein. (83 aa) |
| | USP28 | Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (1144 aa) |
| | TM2D1 | TM2 domain containing 1. (208 aa) |
| | ENSSTOP00000025794 | Uncharacterized protein. (78 aa) |
| | IL33 | Interleukin 33. (264 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) |
| | CTTN | Cortactin. (549 aa) |
| | CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (488 aa) |
| | Bcl2l1 | BH4_2 domain-containing protein. (233 aa) |
| | UBE4B | Ubiquitination factor E4B. (1311 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | UACA | Uveal autoantigen with coiled-coil domains and ankyrin repeats. (1413 aa) |
| | BAG6 | BCL2 associated athanogene 6. (1162 aa) |
| | SCN2A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2006 aa) |
| | ENSSTOP00000024013 | Uncharacterized protein. (102 aa) |
| | Ikbke | Protein kinase domain-containing protein. (130 aa) |
| | LCN2 | Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family. (198 aa) |
| | I3NHC9_ICTTR | 40S ribosomal protein S27. (84 aa) |
| | GPX1 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (201 aa) |
| | ATF4 | Activating transcription factor 4. (352 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1248 aa) |
| | DNAJC10 | DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. (793 aa) |
| | PPARD | Peroxisome proliferator activated receptor delta. (441 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa) |
| | BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (195 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (397 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (383 aa) |
| | FNIP2 | Folliculin interacting protein 2. (1182 aa) |
| | LOC101964473 | Uncharacterized protein; Belongs to the peptidase C14A family. (376 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (634 aa) |
| | KRT8 | Keratin 8; Belongs to the intermediate filament family. (490 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa) |
| | ITPRIP | Inositol 1,4,5-trisphosphate receptor interacting protein. (556 aa) |
| | Foxo3 | Forkhead box O3. (673 aa) |
| | Prdx2 | Thioredoxin domain-containing protein. (198 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) |
| | HIP1 | Huntingtin interacting protein 1. (989 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (480 aa) |
| | HIPK1 | Homeodomain interacting protein kinase 1. (1208 aa) |
| | ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1077 aa) |
| | NDUFA13 | NADH:ubiquinone oxidoreductase subunit A13. (144 aa) |
| | POU4F2 | POU domain protein. (410 aa) |
| | PHLDA3 | Pleckstrin homology like domain family A member 3. (125 aa) |
| | CCK | Cholecystokinin. (115 aa) |
| | SPI1 | Spi-1 proto-oncogene. (270 aa) |
| | I3N9L4_ICTTR | Protein kinase domain-containing protein. (388 aa) |
| | NANOS3 | Nanos C2HC-type zinc finger 3; Belongs to the nanos family. (180 aa) |
| | FAIM2 | Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family. (316 aa) |
| | PERP | P53 apoptosis effector related to PMP22. (193 aa) |
| | NOL3 | Nucleolar protein 3. (210 aa) |
| | Pdcd10 | Programmed cell death 10. (212 aa) |
| | Cd70 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (177 aa) |
| | BOK | BCL2 family apoptosis regulator BOK. (173 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1247 aa) |
| | INHBB | Inhibin subunit beta B. (336 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa) |
| | PTGIS | Prostaglandin I2 synthase; Belongs to the cytochrome P450 family. (414 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (162 aa) |
| | Mllt11 | WRNPLPNID domain-containing protein. (90 aa) |
| | DEDD2 | Death effector domain containing 2. (327 aa) |
| | G0S2 | G0/G1 switch 2. (105 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa) |
| | DAB2IP | DAB2 interacting protein. (1148 aa) |
| | ADORA2A | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (417 aa) |
| | MAPT | Microtubule-associated protein. (430 aa) |
| | CASP8AP2 | Caspase 8 associated protein 2. (1971 aa) |
| | CD28 | CD28 molecule. (221 aa) |
| | Crip1 | LIM zinc-binding domain-containing protein. (77 aa) |
| | PARP2 | Poly [ADP-ribose] polymerase. (566 aa) |
| | ZDHHC3 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (299 aa) |
| | TMEM109 | Transmembrane protein 109. (243 aa) |
| | BAG3 | BCL2 associated athanogene 3. (581 aa) |
| | Hint1 | HIT domain-containing protein. (127 aa) |
| | LOC101959922 | Uncharacterized protein. (442 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa) |
| | FIS1 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa) |
| | HIC1 | HIC ZBTB transcriptional repressor 1. (736 aa) |
| | COA8 | Cytochrome c oxidase assembly factor 8. (170 aa) |
| | CASP6 | Caspase 6; Belongs to the peptidase C14A family. (268 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (982 aa) |
| | POU4F1 | POU domain protein. (294 aa) |
| | TFPT | TCF3 fusion partner. (253 aa) |
| | IER3 | Immediate early response 3. (157 aa) |
| | DDX47 | DEAD-box helicase 47; Belongs to the DEAD box helicase family. (440 aa) |
| | BDKRB2 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (369 aa) |
| | TYROBP | TYRO protein tyrosine kinase binding protein. (113 aa) |
| | MBD4 | Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. (561 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1362 aa) |
| | Ddit3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | BCL2 | BCL2 apoptosis regulator. (195 aa) |
| | MCL1 | MCL1 apoptosis regulator, BCL2 family member. (333 aa) |
| | STK25 | Serine/threonine kinase 25. (421 aa) |
| | I3MU88_ICTTR | Uncharacterized protein. (83 aa) |
| | ITPRIPL2 | ITPRIP like 2. (535 aa) |
| | WWOX | WW domain containing oxidoreductase. (415 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1897 aa) |
| | ARL6IP5 | PRA1 family protein. (152 aa) |
| | I3MTJ0_ICTTR | HIT domain-containing protein. (118 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | GABARAP | GABA type A receptor-associated protein. (117 aa) |
| | BNIP3L | BCL2 interacting protein 3 like. (219 aa) |
| | SIRT1 | Sirtuin 1. (602 aa) |
| | SHH | Sonic hedgehog signaling molecule. (370 aa) |
| | TMEM117 | Transmembrane protein 117. (514 aa) |
| | TNFRSF1B | TNF receptor superfamily member 1B. (436 aa) |
| | RRP8 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (455 aa) |
| | GSKIP | GSK3B interacting protein. (143 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa) |
| | PAWR | Pro-apoptotic WT1 regulator. (340 aa) |
| | ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1038 aa) |
| | KRT18 | Keratin 18; Belongs to the intermediate filament family. (431 aa) |
| | DAPK1 | Death associated protein kinase 1. (1432 aa) |
| | Ggct | Uncharacterized protein. (190 aa) |
| | SFN | Stratifin; Belongs to the 14-3-3 family. (248 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (634 aa) |
| | RNF7 | Ring finger protein 7. (113 aa) |
| | MYBBP1A | MYB binding protein 1a. (1318 aa) |
| | Diablo | Uncharacterized protein. (234 aa) |
| | SIVA1 | Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (175 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | PIDD1 | P53-induced death domain protein 1. (915 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | PML | Promyelocytic leukemia. (877 aa) |
| | PYCARD | PYD and CARD domain containing. (194 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (556 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa) |
| | BNIP3 | BCL2 interacting protein 3. (217 aa) |
| | MKNK2 | MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (461 aa) |
| | FLCN | Folliculin. (579 aa) |
| | Ern2 | Endoplasmic reticulum to nucleus signaling 2. (916 aa) |
| | DIDO1 | Death inducer-obliterator 1. (2246 aa) |
| | ERO1A | Endoplasmic reticulum oxidoreductase 1 alpha. (468 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa) |
| | CHEK2 | Checkpoint kinase 2. (545 aa) |
| | Aen | Exonuclease domain-containing protein. (178 aa) |
| | TRADD | TNFRSF1A associated via death domain. (302 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (520 aa) |
| | SORT1 | Sortilin. (765 aa) |
| | SGPP1 | Sphingosine-1-phosphate phosphatase 1. (428 aa) |
| | PPP1R13B | Protein phosphatase 1 regulatory subunit 13B. (1087 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | SHISA5 | Shisa family member 5. (137 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (437 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4130 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (596 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1005 aa) |
| | E2F2 | E2F transcription factor 2. (432 aa) |
| | TP53BP2 | Tumor protein p53 binding protein 2. (1134 aa) |
| | RRN3 | RRN3 homolog, RNA polymerase I transcription factor. (655 aa) |
| | BCL2A1 | BCL2 related protein A1. (175 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (972 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1307 aa) |
| | Sod2 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (363 aa) |
| | BAD | BCL2 associated agonist of cell death. (208 aa) |
| | AIFM1 | Apoptosis inducing factor mitochondria associated 1. (613 aa) |
| | EDA2R | Ectodysplasin A2 receptor. (297 aa) |
| | SKIL | SKI like proto-oncogene. (677 aa) |
| | LOC101954543 | Uncharacterized protein; Belongs to the peptidase C14A family. (365 aa) |
| | DYRK2 | Dual specificity tyrosine phosphorylation regulated kinase 2. (601 aa) |
| | Faslg | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (69 aa) |
| | DAPL1 | Death associated protein like 1. (110 aa) |
| | CD27 | CD27 molecule. (239 aa) |
| | ANXA6 | Annexin. (673 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | PDIA3 | Protein disulfide-isomerase. (505 aa) |
| | JAK2 | Tyrosine-protein kinase. (1132 aa) |
| | STK24 | Serine/threonine kinase 24. (432 aa) |
| | DEDD | Death effector domain containing. (318 aa) |
| | METTL21C | Methyltransferase like 21C. (263 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (306 aa) |
| | IFI27L2 | Interferon alpha inducible protein 27 like 2. (132 aa) |
| | I3M6A8_ICTTR | Uncharacterized protein. (968 aa) |
| | MLH1 | MutL homolog 1. (758 aa) |
| | EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa) |
| | CRH | Corticotropin releasing hormone. (180 aa) |
| | MELK | Non-specific serine/threonine protein kinase. (641 aa) |
| | NOX1 | NADPH oxidase 1. (561 aa) |
| | CASP2 | Caspase 2; Belongs to the peptidase C14A family. (448 aa) |
| | EYA2 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (551 aa) |
| | ATM | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2618 aa) |
| | LOC101972259 | Uncharacterized protein. (202 aa) |
| | BCL3 | BCL3 transcription coactivator. (440 aa) |
| | EI24 | EI24 autophagy associated transmembrane protein. (326 aa) |
| | Xbp1 | BZIP domain-containing protein. (351 aa) |
| | USP47 | Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa) |
| | NUPR1 | Nuclear protein 1, transcriptional regulator. (81 aa) |
| | Casp3 | Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa) |
| | RNF41 | Ring finger protein 41. (317 aa) |
| | SNW1 | SNW domain containing 1. (554 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1521 aa) |
| | EPHA2 | EPH receptor A2. (923 aa) |
| | RB1CC1 | RB1 inducible coiled-coil 1. (1593 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (890 aa) |
| | E2F1 | E2F transcription factor 1. (392 aa) |
| | XPA | XPA, DNA damage recognition and repair factor. (275 aa) |
| | ATP7A | ATPase copper transporting alpha. (1495 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (437 aa) |
| | DAXX | Death domain associated protein. (740 aa) |
| | SGPL1 | Sphingosine-1-phosphate lyase 1. (568 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (200 aa) |
| | PDE3A | Phosphodiesterase. (1145 aa) |
| | SENP1 | SUMO specific peptidase 1. (645 aa) |
| | QRICH1 | Glutamine rich 1. (778 aa) |
| | UMOD | Uromodulin. (671 aa) |
| | CHAC1 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (222 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa) |
| | LOC101955676 | RING-type domain-containing protein. (326 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (665 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | TMBIM6 | Transmembrane BAX inhibitor motif containing 6; Belongs to the BI1 family. (237 aa) |
| | DELE1 | DAP3 binding cell death enhancer 1. (511 aa) |
| | GSK3A | Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (395 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa) |
| | TIMM50 | Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (353 aa) |
| | EP300 | E1A binding protein p300. (2423 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (228 aa) |
| | ZNF622 | Zinc finger protein 622. (477 aa) |
| | SELENOK | Selenoprotein K. (91 aa) |
| | Brca1 | Uncharacterized protein. (353 aa) |
| | ACVR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa) |
