(21 nodes) Presynaptic modulation of chemical synaptic transmission network (Ictidomys tridecemlineatus)

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Predicted Interactions

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Your Input:
	ERC1	ELKS/RAB6-interacting/CAST family member 1. (1120 aa)
	SYT4	Synaptotagmin 4. (424 aa)
	P2RX7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (596 aa)
	GRIK2	Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa)
	RAB26	RAB26, member RAS oncogene family. (278 aa)
	GIT1	GIT ArfGAP 1. (773 aa)
	CNR1	Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (473 aa)
	FBXL20	F-box and leucine rich repeat protein 20. (436 aa)
	CACNB2	Calcium voltage-gated channel auxiliary subunit beta 2. (657 aa)
	PRKCG	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	Cacnb4	SH3 domain-containing protein. (542 aa)
	LOC101958023	Uncharacterized protein. (111 aa)
	Rpl22	Uncharacterized protein. (169 aa)
	PLEKHG5	Pleckstrin homology and RhoGEF domain containing G5. (1053 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (603 aa)
	FMR1	Fragile X mental retardation 1. (631 aa)
	GIT2	GIT ArfGAP 2. (752 aa)
	CACNA1B	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2316 aa)
	CHRD	Chordin. (898 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACNA1B	CACNB2	ENSSTOP00000004189	ENSSTOP00000024106	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	Calcium voltage-gated channel auxiliary subunit beta 2.	0.941
CACNA1B	Cacnb4	ENSSTOP00000004189	ENSSTOP00000030084	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	SH3 domain-containing protein.	0.926
CACNA1B	PRKCA	ENSSTOP00000004189	ENSSTOP00000002786	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.695
CACNA1B	PRKCB	ENSSTOP00000004189	ENSSTOP00000011139	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.695
CACNA1B	PRKCG	ENSSTOP00000004189	ENSSTOP00000025760	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.832
CACNB2	CACNA1B	ENSSTOP00000024106	ENSSTOP00000004189	Calcium voltage-gated channel auxiliary subunit beta 2.	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	0.941
CACNB2	Cacnb4	ENSSTOP00000024106	ENSSTOP00000030084	Calcium voltage-gated channel auxiliary subunit beta 2.	SH3 domain-containing protein.	0.893
Cacnb4	CACNA1B	ENSSTOP00000030084	ENSSTOP00000004189	SH3 domain-containing protein.	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	0.926
Cacnb4	CACNB2	ENSSTOP00000030084	ENSSTOP00000024106	SH3 domain-containing protein.	Calcium voltage-gated channel auxiliary subunit beta 2.	0.893
ERC1	GIT1	ENSSTOP00000006858	ENSSTOP00000012806	ELKS/RAB6-interacting/CAST family member 1.	GIT ArfGAP 1.	0.445
ERC1	GIT2	ENSSTOP00000006858	ENSSTOP00000004111	ELKS/RAB6-interacting/CAST family member 1.	GIT ArfGAP 2.	0.423
GIT1	ERC1	ENSSTOP00000012806	ENSSTOP00000006858	GIT ArfGAP 1.	ELKS/RAB6-interacting/CAST family member 1.	0.445
GIT1	GIT2	ENSSTOP00000012806	ENSSTOP00000004111	GIT ArfGAP 1.	GIT ArfGAP 2.	0.899
GIT2	ERC1	ENSSTOP00000004111	ENSSTOP00000006858	GIT ArfGAP 2.	ELKS/RAB6-interacting/CAST family member 1.	0.423
GIT2	GIT1	ENSSTOP00000004111	ENSSTOP00000012806	GIT ArfGAP 2.	GIT ArfGAP 1.	0.899
PRKCA	CACNA1B	ENSSTOP00000002786	ENSSTOP00000004189	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	0.695
PRKCA	PRKCG	ENSSTOP00000002786	ENSSTOP00000025760	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.904
PRKCB	CACNA1B	ENSSTOP00000011139	ENSSTOP00000004189	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	0.695
PRKCB	PRKCG	ENSSTOP00000011139	ENSSTOP00000025760	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.904
PRKCG	CACNA1B	ENSSTOP00000025760	ENSSTOP00000004189	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	0.832