STRINGSTRING
PRKCG PRKCG FBXO45 FBXO45 FMR1 FMR1 HOMER1 HOMER1 PRKCA PRKCA EIF4E EIF4E RIMS3 RIMS3 LRRK2 LRRK2 ALDOC ALDOC PRKCD PRKCD PIN1 PIN1 Eif4ebp1 Eif4ebp1 BAIAP2 BAIAP2 MTOR MTOR ENSSTOP00000030920 ENSSTOP00000030920 ENSSTOP00000030697 ENSSTOP00000030697 PLCB3 PLCB3 HNRNPA2B1 HNRNPA2B1 DAG1 DAG1 DBN1 DBN1 PRKCE PRKCE PRKCB PRKCB ANKS1B ANKS1B MARCKSL1 MARCKSL1 TRIM9 TRIM9 HTT HTT CALB1 CALB1 CAMK2A CAMK2A STXBP5 STXBP5 PPFIA2 PPFIA2 PPP3CC PPP3CC PTEN PTEN ENSSTOP00000028389 ENSSTOP00000028389 ENSSTOP00000027688 ENSSTOP00000027688 DNAJB1 DNAJB1 HNRNPAB HNRNPAB SNCB SNCB HAP1 HAP1 I3N8Q7_ICTTR I3N8Q7_ICTTR I3N998_ICTTR I3N998_ICTTR CTBP2 CTBP2 EIF4A3 EIF4A3 NEDD4 NEDD4 ENSSTOP00000026667 ENSSTOP00000026667
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
FBXO45F-box protein 45. (251 aa)
FMR1Fragile X mental retardation 1. (631 aa)
HOMER1Homer scaffold protein 1. (363 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (603 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (218 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
LRRK2Leucine rich repeat kinase 2. (2520 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
Eif4ebp1Uncharacterized protein. (118 aa)
BAIAP2BAI1 associated protein 2. (535 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2577 aa)
ENSSTOP00000030920Uncharacterized protein. (284 aa)
ENSSTOP00000030697RRM domain-containing protein. (311 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1255 aa)
HNRNPA2B1Uncharacterized protein. (353 aa)
DAG1Dystroglycan 1. (895 aa)
DBN1Drebrin 1. (679 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa)
ANKS1BAnkyrin repeat and sterile alpha motif domain containing 1B. (1260 aa)
MARCKSL1MARCKS like 1. (178 aa)
TRIM9Tripartite motif containing 9. (788 aa)
HTTHuntingtin. (3114 aa)
CALB1Calbindin 1. (261 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
STXBP5Syntaxin binding protein 5. (964 aa)
PPFIA2PTPRF interacting protein alpha 2. (1174 aa)
PPP3CCSerine/threonine-protein phosphatase. (487 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
ENSSTOP00000028389Uncharacterized protein. (113 aa)
ENSSTOP00000027688Uncharacterized protein. (316 aa)
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (340 aa)
HNRNPABHeterogeneous nuclear ribonucleoprotein A/B. (331 aa)
SNCBBeta-synuclein; Belongs to the synuclein family. (134 aa)
HAP1Huntingtin associated protein 1. (638 aa)
I3N8Q7_ICTTRUncharacterized protein. (292 aa)
I3N998_ICTTRUncharacterized protein. (305 aa)
CTBP2C-terminal binding protein 2. (985 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
NEDD4E3 ubiquitin-protein ligase. (901 aa)
ENSSTOP00000026667Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (430 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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