STRINGSTRING
ATM ATM MAPK3 MAPK3 TNKS2 TNKS2 ERCC1 ERCC1 MAP3K4 MAP3K4 Rad50 Rad50 Rtel1 Rtel1 ERCC4 ERCC4 NEK7 NEK7 HNRNPD HNRNPD NEK2 NEK2 TNKS TNKS MAPK1 MAPK1 NBN NBN NABP2 NABP2 XRCC1 XRCC1 MAPK15 MAPK15 PRKCQ PRKCQ PNKP PNKP XRCC4 XRCC4 SMG6 SMG6 MAPKAPK5 MAPKAPK5 PKIB PKIB MAP2K7 MAP2K7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATMATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2618 aa)
MAPK3Mitogen-activated protein kinase. (361 aa)
TNKS2Poly [ADP-ribose] polymerase. (1155 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1553 aa)
Rad50Zinc-hook domain-containing protein. (1312 aa)
Rtel1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1256 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
NEK7NIMA related kinase 7; Belongs to the protein kinase superfamily. (302 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D. (356 aa)
NEK2NIMA related kinase 2. (445 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
MAPK1Mitogen-activated protein kinase. (331 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (634 aa)
NABP2Nucleic acid binding protein 2. (211 aa)
XRCC1X-ray repair cross complementing 1. (632 aa)
MAPK15Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (554 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
PNKPPolynucleotide kinase 3'-phosphatase. (520 aa)
XRCC4X-ray repair cross complementing 4. (330 aa)
SMG6SMG6 nonsense mediated mRNA decay factor. (1418 aa)
MAPKAPK5MAPK activated protein kinase 5. (472 aa)
PKIBcAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (78 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (469 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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