STRINGSTRING
ERCC6 ERCC6 TAF6 TAF6 Med17 Med17 IKZF1 IKZF1 TAF4B TAF4B TAF13 TAF13 ENSSTOP00000030597 ENSSTOP00000030597 ENSSTOP00000029470 ENSSTOP00000029470 MED18 MED18 ENSSTOP00000028056 ENSSTOP00000028056 ENSSTOP00000026771 ENSSTOP00000026771 MED14 MED14 GTF2A2 GTF2A2 MED24 MED24 SUB1 SUB1 JUN JUN CAND1 CAND1 SETX SETX TP53 TP53 TAF2 TAF2 MED1 MED1 Pou5f1 Pou5f1 CREB1 CREB1 MED12 MED12 TAF8 TAF8 MED16 MED16 TAF4 TAF4 TAF5 TAF5 SRF SRF BCLAF1 BCLAF1 Taf11 Taf11 HNF1B HNF1B TAF7 TAF7 TAF3 TAF3 MED30 MED30 TAF12 TAF12 FOSL1 FOSL1 DHX36 DHX36 WNT10B WNT10B NKX2-5 NKX2-5 HNF1A HNF1A MITF MITF GTF2A1 GTF2A1 ERCC1 ERCC1 XPA XPA MED4 MED4 Ahr Ahr TAF10 TAF10 MED13 MED13 MED8 MED8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1521 aa)
TAF6TATA-box binding protein associated factor 6. (678 aa)
Med17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (651 aa)
IKZF1IKAROS family zinc finger 1. (539 aa)
TAF4BTATA-box binding protein associated factor 4b. (855 aa)
TAF13TATA-box binding protein associated factor 13. (124 aa)
ENSSTOP00000030597Uncharacterized protein. (100 aa)
ENSSTOP00000029470POU-specific domain-containing protein. (311 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa)
ENSSTOP00000028056PC4 domain-containing protein. (100 aa)
ENSSTOP00000026771PC4 domain-containing protein. (134 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1454 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
MED24Mediator complex subunit 24. (1008 aa)
SUB1SUB1 regulator of transcription. (127 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
CAND1Cullin associated and neddylation dissociated 1. (1212 aa)
SETXSenataxin. (2708 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa)
TAF2TATA-box binding protein associated factor 2. (1212 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1575 aa)
Pou5f1POU domain protein. (360 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
MED12Mediator complex subunit 12. (2146 aa)
TAF8TATA-box binding protein associated factor 8. (310 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (866 aa)
TAF4TATA-box binding protein associated factor 4. (636 aa)
TAF5TATA-box binding protein associated factor 5. (787 aa)
SRFSerum response factor. (505 aa)
BCLAF1BCL2 associated transcription factor 1. (933 aa)
Taf11TATA-box binding protein associated factor 11. (211 aa)
HNF1BHNF1 homeobox B. (558 aa)
TAF7TATA-box binding protein associated factor 7. (349 aa)
TAF3TATA-box binding protein associated factor 3. (930 aa)
MED30Mediator complex subunit 30. (152 aa)
TAF12TATA-box binding protein associated factor 12. (213 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (275 aa)
DHX36DEAH-box helicase 36. (1000 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
NKX2-5NK2 homeobox 5. (321 aa)
HNF1AHNF1 homeobox A. (449 aa)
MITFMelanocyte inducing transcription factor. (482 aa)
GTF2A1General transcription factor IIA subunit 1. (366 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa)
XPAXPA, DNA damage recognition and repair factor. (275 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
AhrUncharacterized protein. (848 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
MED13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2173 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (268 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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