(66 nodes) Negative regulation of reproductive process network (Ictidomys tridecemlineatus)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	LOC101956987	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (180 aa)
	IGF1	Insulin like growth factor 1. (166 aa)
	ARHGDIB	Rho GDP dissociation inhibitor beta. (200 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	NKX3-1	NK3 homeobox 1. (144 aa)
	SPINK13	Serine peptidase inhibitor, Kazal type 13 (putative). (97 aa)
	HPGDS	Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (204 aa)
	HYAL3	Hyaluronidase. (415 aa)
	OVGP1	Oviductal glycoprotein 1; Belongs to the glycosyl hydrolase 18 family. (517 aa)
	PTGDR2	Prostaglandin D2 receptor 2; Belongs to the G-protein coupled receptor 1 family. (404 aa)
	ZP1	Zona pellucida glycoprotein 1. (619 aa)
	HORMAD1	HORMA domain containing 1. (364 aa)
	LOC101972479	A_deaminase domain-containing protein. (338 aa)
	Shb	SH2 domain-containing protein. (495 aa)
	SERPINF1	Serpin family F member 1; Belongs to the serpin family. (417 aa)
	FBXO43	F-box protein 43. (706 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
	SULF1	Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
	OVOL1	Ovo like transcriptional repressor 1. (267 aa)
	STK11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (437 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (334 aa)
	PRDX4	Peroxiredoxin 4. (272 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	WNT4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
	NR5A1	Nuclear receptor subfamily 5 group A member 1. (461 aa)
	TPST2	Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family. (318 aa)
	CDKN1B	Cyclin dependent kinase inhibitor 1B. (198 aa)
	TRIP13	Thyroid hormone receptor interactor 13. (349 aa)
	LOC101974752	Uncharacterized protein. (134 aa)
	GRB14	Growth factor receptor bound protein 14. (540 aa)
	RGN	Regucalcin. (299 aa)
	NODAL	Nodal growth differentiation factor. (350 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	Osm	Uncharacterized protein. (214 aa)
	ASTL	Metalloendopeptidase. (413 aa)
	DMRT1	Doublesex and mab-3 related transcription factor 1. (371 aa)
	PLAT	Plasminogen activator; Belongs to the peptidase S1 family. (560 aa)
	RAD1	RAD1 checkpoint DNA exonuclease. (279 aa)
	CALR	Calreticulin. (418 aa)
	DDB1	Damage specific DNA binding protein 1. (1140 aa)
	ZP2	Zona pellucida glycoprotein 2. (695 aa)
	NPR2	Guanylate cyclase. (1047 aa)
	I3M7E8_ICTTR	Uncharacterized protein. (157 aa)
	LIF	LIF interleukin 6 family cytokine. (202 aa)
	TIMP1	TIMP metallopeptidase inhibitor 1. (206 aa)
	SNAI1	Snail family transcriptional repressor 1. (264 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (733 aa)
	GPR149	G protein-coupled receptor 149. (731 aa)
	ACVR1C	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
	APC	APC regulator of WNT signaling pathway. (2865 aa)
	ENSSTOP00000030629	SYCP2_ARLD domain-containing protein. (200 aa)
	FBXO5	F-box protein 5. (450 aa)
	DUSP1	Dual specificity phosphatase 1. (272 aa)
	LOC101972772	A_deaminase domain-containing protein. (352 aa)
	WDR77	WD repeat domain 77. (342 aa)
	NPPC	Natriuretic peptide C. (126 aa)
	MYH9	Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
	I3N1G5_ICTTR	Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (1263 aa)
	WT1	WT1 transcription factor. (523 aa)
	Nanos2	Nanos C2HC-type zinc finger 2; Belongs to the nanos family. (130 aa)
	MOS	MOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (349 aa)
	CHFR	Checkpoint with forkhead and ring finger domains. (724 aa)
	AMH	Anti-Mullerian hormone. (545 aa)
	EAF2	ELL associated factor 2. (263 aa)
	ZFPM2	Zinc finger protein, FOG family member 2. (1149 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACVR1C	AMH	ENSSTOP00000032180	ENSSTOP00000015446	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Anti-Mullerian hormone.	0.729
ACVR1C	APC	ENSSTOP00000032180	ENSSTOP00000031860	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	APC regulator of WNT signaling pathway.	0.412
ACVR1C	BMP4	ENSSTOP00000032180	ENSSTOP00000001023	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Bone morphogenetic protein 4.	0.852
ACVR1C	BMP7	ENSSTOP00000032180	ENSSTOP00000011380	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Bone morphogenetic protein 7.	0.657
ACVR1C	NODAL	ENSSTOP00000032180	ENSSTOP00000011597	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Nodal growth differentiation factor.	0.919
AMH	ACVR1C	ENSSTOP00000015446	ENSSTOP00000032180	Anti-Mullerian hormone.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.729
AMH	DMRT1	ENSSTOP00000015446	ENSSTOP00000009178	Anti-Mullerian hormone.	Doublesex and mab-3 related transcription factor 1.	0.607
AMH	NR5A1	ENSSTOP00000015446	ENSSTOP00000000357	Anti-Mullerian hormone.	Nuclear receptor subfamily 5 group A member 1.	0.653
AMH	SPINK13	ENSSTOP00000015446	ENSSTOP00000025274	Anti-Mullerian hormone.	Serine peptidase inhibitor, Kazal type 13 (putative).	0.404
AMH	WNT4	ENSSTOP00000015446	ENSSTOP00000000720	Anti-Mullerian hormone.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.467
AMH	WT1	ENSSTOP00000015446	ENSSTOP00000016765	Anti-Mullerian hormone.	WT1 transcription factor.	0.657
APC	ACVR1C	ENSSTOP00000031860	ENSSTOP00000032180	APC regulator of WNT signaling pathway.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.412
APC	MOS	ENSSTOP00000031860	ENSSTOP00000015800	APC regulator of WNT signaling pathway.	MOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily.	0.412
ARHGDIB	HYAL3	ENSSTOP00000029344	ENSSTOP00000024109	Rho GDP dissociation inhibitor beta.	Hyaluronidase.	0.533
ARHGDIB	PRKACA	ENSSTOP00000029344	ENSSTOP00000002080	Rho GDP dissociation inhibitor beta.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.843
ARHGDIB	PRKACB	ENSSTOP00000029344	ENSSTOP00000028928	Rho GDP dissociation inhibitor beta.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.848
BMP4	ACVR1C	ENSSTOP00000001023	ENSSTOP00000032180	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.852
BMP4	BMP7	ENSSTOP00000001023	ENSSTOP00000011380	Bone morphogenetic protein 4.	Bone morphogenetic protein 7.	0.902
BMP4	SPINK13	ENSSTOP00000001023	ENSSTOP00000025274	Bone morphogenetic protein 4.	Serine peptidase inhibitor, Kazal type 13 (putative).	0.404
BMP4	WNT5A	ENSSTOP00000001023	ENSSTOP00000020681	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.434