STRINGSTRING
GLRA3 GLRA3 ENSSTOP00000032175 ENSSTOP00000032175 RAB3GAP1 RAB3GAP1 CDK5 CDK5 BACE1 BACE1 FMR1 FMR1 DRD2 DRD2 NR3C2 NR3C2 ADORA2B ADORA2B SYP SYP GIT2 GIT2 CYTH1 CYTH1 Nrn1 Nrn1 Cacnb4 Cacnb4 MYO6 MYO6 CHRNB3 CHRNB3 APBA1 APBA1 NLGN1 NLGN1 CHRNB2 CHRNB2 ENSSTOP00000026508 ENSSTOP00000026508 P2RX1 P2RX1 PRKCG PRKCG APBA2 APBA2 Bcl2l1 Bcl2l1 ATP2A2 ATP2A2 CACNB2 CACNB2 PRKCA PRKCA RAB3A RAB3A BRAF BRAF GRIN3A GRIN3A CHRNA6 CHRNA6 RIMS3 RIMS3 DGKI DGKI SNAPIN SNAPIN LRRK2 LRRK2 SLC4A8 SLC4A8 CHRM2 CHRM2 FBXL20 FBXL20 RAB5A RAB5A GSK3B GSK3B I3NE76_ICTTR I3NE76_ICTTR CNR1 CNR1 RIMS4 RIMS4 I3N998_ICTTR I3N998_ICTTR P2RY1 P2RY1 P2RY2 P2RY2 VPS18 VPS18 I3N0K9_ICTTR I3N0K9_ICTTR DRD4 DRD4 HTR1A HTR1A I3MW25_ICTTR I3MW25_ICTTR SYT1 SYT1 DRD1 DRD1 CSPG5 CSPG5 P2RY4 P2RY4 RAP1A RAP1A CHRNA4 CHRNA4 NRXN3 NRXN3 GIPC2 GIPC2 GIT1 GIT1 PPFIA2 PPFIA2 GIPC1 GIPC1 DVL1 DVL1 PRKCE PRKCE PRKCB PRKCB KCNH1 KCNH1 GRM7 GRM7 SYNPR SYNPR CASK CASK PREPL PREPL CACNA1B CACNA1B GRM8 GRM8 GIPC3 GIPC3 DNM1L DNM1L RAP1B RAP1B PFN2 PFN2 STXBP5L STXBP5L P2RX7 P2RX7 SYT4 SYT4 ADCY1 ADCY1 STXBP5 STXBP5 ERC1 ERC1 CHRNA3 CHRNA3 CHRNA5 CHRNA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLRA3Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (469 aa)
ENSSTOP00000032175Uncharacterized protein. (123 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (987 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)
FMR1Fragile X mental retardation 1. (631 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
NR3C2Nuclear receptor subfamily 3 group C member 2. (985 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa)
SYPSynaptophysin. (313 aa)
GIT2GIT ArfGAP 2. (752 aa)
CYTH1Cytohesin 1. (389 aa)
Nrn1Uncharacterized protein. (176 aa)
Cacnb4SH3 domain-containing protein. (542 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1294 aa)
CHRNB3Cholinergic receptor nicotinic beta 3 subunit. (459 aa)
APBA1Amyloid beta precursor protein binding family A member 1. (837 aa)
NLGN1Neuroligin 1. (843 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (599 aa)
ENSSTOP00000026508BH4_2 domain-containing protein. (224 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (398 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
APBA2Amyloid beta precursor protein binding family A member 2. (750 aa)
Bcl2l1BH4_2 domain-containing protein. (233 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (657 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (603 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (754 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1115 aa)
CHRNA6Cholinergic receptor nicotinic alpha 6 subunit. (494 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
DGKIDiacylglycerol kinase. (960 aa)
SNAPINSNAP associated protein. (125 aa)
LRRK2Leucine rich repeat kinase 2. (2520 aa)
SLC4A8Anion exchange protein. (1090 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
FBXL20F-box and leucine rich repeat protein 20. (436 aa)
RAB5ARAB5A, member RAS oncogene family. (215 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
I3NE76_ICTTRUncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (435 aa)
CNR1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (473 aa)
RIMS4Regulating synaptic membrane exocytosis 4. (269 aa)
I3N998_ICTTRUncharacterized protein. (305 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
P2RY2Purinergic receptor P2Y2; Belongs to the G-protein coupled receptor 1 family. (376 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (973 aa)
I3N0K9_ICTTRUncharacterized protein. (198 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (374 aa)
HTR1A5-hydroxytryptamine receptor 1A. (423 aa)
I3MW25_ICTTRUncharacterized protein. (144 aa)
SYT1Synaptotagmin 1. (422 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (445 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (550 aa)
P2RY4Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family. (358 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
CHRNA4Cholinergic receptor nicotinic alpha 4 subunit. (617 aa)
NRXN3Neurexin 3. (1571 aa)
GIPC2GIPC PDZ domain containing family member 2. (315 aa)
GIT1GIT ArfGAP 1. (773 aa)
PPFIA2PTPRF interacting protein alpha 2. (1174 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
DVL1Dishevelled segment polarity protein 1. (696 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa)
KCNH1Potassium voltage-gated channel subfamily H member 1. (962 aa)
GRM7Glutamate metabotropic receptor 7. (629 aa)
SYNPRSynaptoporin. (285 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (930 aa)
PREPLProlyl endopeptidase like. (727 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2316 aa)
GRM8Glutamate metabotropic receptor 8. (908 aa)
GIPC3GIPC PDZ domain containing family member 3. (312 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
RAP1BRAP1B, member of RAS oncogene family. (159 aa)
PFN2Profilin; Belongs to the profilin family. (91 aa)
STXBP5LSyntaxin binding protein 5 like. (1186 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (596 aa)
SYT4Synaptotagmin 4. (424 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
STXBP5Syntaxin binding protein 5. (964 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1120 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (502 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (468 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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