(20 nodes) Positive regulation of transcription regulatory region DNA binding network (Ictidomys tridecemlineatus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	POU4F1	POU domain protein. (294 aa)
	EP300	E1A binding protein p300. (2423 aa)
	RB1	RB transcriptional corepressor 1. (957 aa)
	GATA3	GATA binding protein 3. (444 aa)
	PAX6	Paired box 6. (436 aa)
	LAMTOR5	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa)
	DDRGK1	DDRGK domain containing 1. (306 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	NIBAN2	Niban apoptosis regulator 2. (749 aa)
	NEUROD1	Neurogenic differentiation factor. (356 aa)
	HAND2	Heart and neural crest derivatives expressed 2. (217 aa)
	POU4F2	POU domain protein. (410 aa)
	H1-0	H1 histone family member 0. (194 aa)
	TRIM6	Tripartite motif containing 6. (469 aa)
	I3NG54_ICTTR	Uncharacterized protein. (91 aa)
	GTF2B	General transcription factor IIB. (316 aa)
	IGF1	Insulin like growth factor 1. (166 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTNNB1	EP300	ENSSTOP00000014441	ENSSTOP00000000650	Catenin beta 1.	E1A binding protein p300.	0.993
CTNNB1	PARP1	ENSSTOP00000014441	ENSSTOP00000014322	Catenin beta 1.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.401
CTNNB1	PAX6	ENSSTOP00000014441	ENSSTOP00000002864	Catenin beta 1.	Paired box 6.	0.433
CTNNB1	TGFB1	ENSSTOP00000014441	ENSSTOP00000008874	Catenin beta 1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.471
EP300	CTNNB1	ENSSTOP00000000650	ENSSTOP00000014441	E1A binding protein p300.	Catenin beta 1.	0.993
EP300	GATA3	ENSSTOP00000000650	ENSSTOP00000000959	E1A binding protein p300.	GATA binding protein 3.	0.912
EP300	GTF2B	ENSSTOP00000000650	ENSSTOP00000028315	E1A binding protein p300.	General transcription factor IIB.	0.812
EP300	NEUROD1	ENSSTOP00000000650	ENSSTOP00000019657	E1A binding protein p300.	Neurogenic differentiation factor.	0.418
EP300	PARP1	ENSSTOP00000000650	ENSSTOP00000014322	E1A binding protein p300.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.745
EP300	PAX6	ENSSTOP00000000650	ENSSTOP00000002864	E1A binding protein p300.	Paired box 6.	0.693
EP300	RB1	ENSSTOP00000000650	ENSSTOP00000000834	E1A binding protein p300.	RB transcriptional corepressor 1.	0.596
EP300	TGFB1	ENSSTOP00000000650	ENSSTOP00000008874	E1A binding protein p300.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.691
GATA3	EP300	ENSSTOP00000000959	ENSSTOP00000000650	GATA binding protein 3.	E1A binding protein p300.	0.912
GATA3	HAND2	ENSSTOP00000000959	ENSSTOP00000020619	GATA binding protein 3.	Heart and neural crest derivatives expressed 2.	0.658
GTF2B	EP300	ENSSTOP00000028315	ENSSTOP00000000650	General transcription factor IIB.	E1A binding protein p300.	0.812
H1-0	PARP1	ENSSTOP00000022420	ENSSTOP00000014322	H1 histone family member 0.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.423
HAND2	GATA3	ENSSTOP00000020619	ENSSTOP00000000959	Heart and neural crest derivatives expressed 2.	GATA binding protein 3.	0.658
IGF1	TGFB1	ENSSTOP00000029785	ENSSTOP00000008874	Insulin like growth factor 1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.645
NEUROD1	EP300	ENSSTOP00000019657	ENSSTOP00000000650	Neurogenic differentiation factor.	E1A binding protein p300.	0.418
NEUROD1	PAX6	ENSSTOP00000019657	ENSSTOP00000002864	Neurogenic differentiation factor.	Paired box 6.	0.571