STRINGSTRING
Tubb3 Tubb3 NDRG2 NDRG2 BOC BOC DPYSL2 DPYSL2 FEZ1 FEZ1 DSCAM DSCAM Ywhae Ywhae CBL CBL THY1 THY1 UTRN UTRN Dynlt1 Dynlt1 CXCR4 CXCR4 DPYSL3 DPYSL3 LOC101963675 LOC101963675 STX3 STX3 CRMP1 CRMP1 NTRK2 NTRK2 FLRT3 FLRT3 APBB1 APBB1 HSP90AA1 HSP90AA1 C9orf72 C9orf72 SMO SMO SSH1 SSH1 PTBP2 PTBP2 ZFYVE27 ZFYVE27 TRPV2 TRPV2 NEO1 NEO1 LOC101965836 LOC101965836 PAK1 PAK1 LIMK1 LIMK1 DVL1 DVL1 MYO9A MYO9A LRP1 LRP1 KIF3C KIF3C Fgf13 Fgf13 RAC3 RAC3 CDKL5 CDKL5 TAOK2 TAOK2 UNC5C UNC5C PARD3 PARD3 CALM1 CALM1 SIRT1 SIRT1 STMN2 STMN2 Gap43 Gap43 HNRNPR HNRNPR Ppp1r9b Ppp1r9b DCC DCC Cpeb1 Cpeb1 MAPK8IP1 MAPK8IP1 I3N055_ICTTR I3N055_ICTTR TOR1A TOR1A DCX DCX MAP3K12 MAP3K12 COPG2 COPG2 MAPT MAPT ADGRL1 ADGRL1 NIN NIN SNCB SNCB ACAP3 ACAP3 HAP1 HAP1 MAP2 MAP2 SETX SETX GPM6A GPM6A ABITRAM ABITRAM PTPRZ1 PTPRZ1 HSP90AB1 HSP90AB1 OLFM1 OLFM1 CNR1 CNR1 I3NE76_ICTTR I3NE76_ICTTR CALM2 CALM2 I3NFL4_ICTTR I3NFL4_ICTTR LOC101975245 LOC101975245 GSK3B GSK3B SHTN1 SHTN1 DICER1 DICER1 Ppp1r9a Ppp1r9a RTN4R RTN4R FKBP4 FKBP4 ENSSTOP00000023976 ENSSTOP00000023976 CYFIP1 CYFIP1 DLG3 DLG3 KIF5B KIF5B EXOC7 EXOC7 RUFY3 RUFY3 DCLK1 DCLK1 TRPV4 TRPV4 MYH10 MYH10 TRPC5 TRPC5 PTPRF PTPRF ENSSTOP00000025656 ENSSTOP00000025656 HDAC5 HDAC5 ENSSTOP00000025799 ENSSTOP00000025799 GRIA2 GRIA2 ELAVL4 ELAVL4 LMTK2 LMTK2 ENSSTOP00000025973 ENSSTOP00000025973 ALS2 ALS2 LOC101959679 LOC101959679 CIB1 CIB1 APP APP ARPC3 ARPC3 CALM3 CALM3 ENO2 ENO2 STIM1 STIM1 IQGAP1 IQGAP1 ERC2 ERC2 ARHGEF7 ARHGEF7 KIF5C KIF5C DBN1 DBN1 NCAM1 NCAM1 LRP2 LRP2 TSHZ3 TSHZ3 AGRN AGRN KLC1 KLC1 ENSSTOP00000029937 ENSSTOP00000029937 ENSSTOP00000030319 ENSSTOP00000030319 PTCH1 PTCH1 ENSSTOP00000031279 ENSSTOP00000031279 APC APC TRAK2 TRAK2 TENM2 TENM2 ENSSTOP00000032237 ENSSTOP00000032237 L1CAM L1CAM ARPC5 ARPC5 TSC1 TSC1 I3M249_ICTTR I3M249_ICTTR ADCY10 ADCY10 EPHA4 EPHA4 MAP1B MAP1B INPP5J INPP5J SYAP1 SYAP1 RAPGEF4 RAPGEF4 RAPGEF3 RAPGEF3 I3LX54_ICTTR I3LX54_ICTTR LRIG2 LRIG2 LAMP5 LAMP5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tubb3Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
NDRG2NDRG family member 2. (371 aa)
BOCBOC cell adhesion associated, oncogene regulated. (1115 aa)
DPYSL2Dihydropyrimidinase like 2. (677 aa)
FEZ1Fasciculation and elongation protein zeta 1. (219 aa)
DSCAMDS cell adhesion molecule. (2012 aa)
Ywhae14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
CBLCbl proto-oncogene. (870 aa)
THY1Thy-1 cell surface antigen. (162 aa)
UTRNUtrophin. (3191 aa)
Dynlt1Uncharacterized protein. (113 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (352 aa)
DPYSL3Dihydropyrimidinase like 3. (684 aa)
LOC101963675Uncharacterized protein. (215 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (287 aa)
CRMP1Collapsin response mediator protein 1. (619 aa)
NTRK2Tyrosine-protein kinase receptor. (821 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
APBB1Amyloid beta precursor protein binding family B member 1. (708 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (733 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
SSH1Slingshot protein phosphatase 1. (1016 aa)
PTBP2Polypyrimidine tract binding protein 2. (529 aa)
ZFYVE27Zinc finger FYVE-type containing 27. (409 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (758 aa)
NEO1Neogenin 1. (1440 aa)
LOC101965836Tudor domain-containing protein. (274 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
LIMK1LIM domain kinase 1. (628 aa)
DVL1Dishevelled segment polarity protein 1. (696 aa)
MYO9AMyosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2638 aa)
LRP1LDL receptor related protein 1. (4508 aa)
KIF3CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (794 aa)
Fgf13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
RAC3Rac family small GTPase 3. (185 aa)
CDKL5Cyclin dependent kinase like 5. (960 aa)
TAOK2TAO kinase 2. (1240 aa)
UNC5CUnc-5 netrin receptor C. (916 aa)
PARD3Par-3 family cell polarity regulator. (1296 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (148 aa)
SIRT1Sirtuin 1. (602 aa)
STMN2Stathmin; Belongs to the stathmin family. (179 aa)
Gap43Uncharacterized protein. (231 aa)
HNRNPRHeterogeneous nuclear ribonucleoprotein R. (633 aa)
Ppp1r9bPDZ domain-containing protein. (361 aa)
DCCDCC netrin 1 receptor. (1447 aa)
Cpeb1Uncharacterized protein. (566 aa)
MAPK8IP1Mitogen-activated protein kinase 8 interacting protein 1. (697 aa)
I3N055_ICTTRCobl domain-containing protein. (335 aa)
TOR1ATorsin. (311 aa)
DCXDoublecortin. (360 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (890 aa)
COPG2Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (871 aa)
MAPTMicrotubule-associated protein. (430 aa)
ADGRL1Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. (1512 aa)
NINNinein. (2136 aa)
SNCBBeta-synuclein; Belongs to the synuclein family. (134 aa)
ACAP3ArfGAP with coiled-coil, ankyrin repeat and PH domains 3. (786 aa)
HAP1Huntingtin associated protein 1. (638 aa)
MAP2Microtubule-associated protein. (1878 aa)
SETXSenataxin. (2708 aa)
GPM6AGlycoprotein M6A. (278 aa)
ABITRAMActin binding transcription modulator. (179 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2277 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
OLFM1Olfactomedin 1. (435 aa)
CNR1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (473 aa)
I3NE76_ICTTRUncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (435 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
I3NFL4_ICTTRUncharacterized protein. (573 aa)
LOC101975245HATPase_c domain-containing protein. (733 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
SHTN1Shootin 1. (611 aa)
DICER1Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1904 aa)
Ppp1r9aUncharacterized protein. (446 aa)
RTN4RReticulon 4 receptor. (473 aa)
FKBP4Peptidylprolyl isomerase. (459 aa)
ENSSTOP00000023976Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (151 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (867 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (697 aa)
RUFY3RUN and FYVE domain containing 3. (583 aa)
DCLK1Doublecortin like kinase 1. (761 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1908 aa)
ENSSTOP00000025656Uncharacterized protein. (113 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1113 aa)
ENSSTOP00000025799LAM_G_DOMAIN domain-containing protein. (176 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (402 aa)
LMTK2Lemur tyrosine kinase 2. (1485 aa)
ENSSTOP0000002597314_3_3 domain-containing protein. (119 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1657 aa)
LOC101959679Uncharacterized protein. (767 aa)
CIB1Calcium and integrin binding 1. (191 aa)
APPAmyloid beta precursor protein. (739 aa)
ARPC3Actin related protein 2/3 complex subunit 3. (102 aa)
CALM3Calmodulin 3. (149 aa)
ENO2Enolase 2. (434 aa)
STIM1Stromal interaction molecule 1. (716 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (991 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (713 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa)
DBN1Drebrin 1. (679 aa)
NCAM1Neural cell adhesion molecule 1. (1019 aa)
LRP2LDL receptor related protein 2. (4656 aa)
TSHZ3Teashirt zinc finger homeobox 3. (1089 aa)
AGRNAgrin. (1964 aa)
KLC1Kinesin light chain 1. (616 aa)
ENSSTOP00000029937Uncharacterized protein; Belongs to the calmodulin family. (67 aa)
ENSSTOP00000030319Uncharacterized protein. (2101 aa)
PTCH1Patched 1. (1450 aa)
ENSSTOP00000031279Uncharacterized protein. (117 aa)
APCAPC regulator of WNT signaling pathway. (2865 aa)
TRAK2Trafficking kinesin protein 2. (914 aa)
TENM2Teneurin transmembrane protein 2. (2765 aa)
ENSSTOP00000032237Uncharacterized protein; Belongs to the calmodulin family. (148 aa)
L1CAML1 cell adhesion molecule. (1256 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
TSC1TSC complex subunit 1. (1164 aa)
I3M249_ICTTRUncharacterized protein. (683 aa)
ADCY10Adenylate cyclase 10. (1610 aa)
EPHA4EPH receptor A4. (986 aa)
MAP1BMicrotubule associated protein 1B. (2469 aa)
INPP5JInositol polyphosphate-5-phosphatase J. (1002 aa)
SYAP1Synapse associated protein 1. (358 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (985 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (898 aa)
I3LX54_ICTTRUncharacterized protein. (327 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1062 aa)
LAMP5Lysosomal associated membrane protein family member 5. (264 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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