90 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101962681	Aminotran_1_2 domain-containing protein. (408 aa)
	ESR2	Estrogen receptor 2. (525 aa)
	HNRNPA2B1	Uncharacterized protein. (353 aa)
	ENSSTOP00000029768	Aminotran_1_2 domain-containing protein. (365 aa)
	NGB	Neuroglobin; Belongs to the globin family. (140 aa)
	ASS1	Argininosuccinate synthase 1. (412 aa)
	HPCAL1	Hippocalcin like 1. (193 aa)
	MAPK10	Mitogen-activated protein kinase. (492 aa)
	PDE10A	Phosphodiesterase. (794 aa)
	MAP1B	Microtubule associated protein 1B. (2469 aa)
	ATP7A	ATPase copper transporting alpha. (1495 aa)
	EPHA4	EPH receptor A4. (986 aa)
	DIP2B	Disco interacting protein 2 homolog B. (1576 aa)
	DHX36	DEAH-box helicase 36. (1000 aa)
	KCNC2	Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (640 aa)
	LOC101968704	Uncharacterized protein. (1203 aa)
	CRH	Corticotropin releasing hormone. (180 aa)
	ERCC8	ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa)
	FUS	FUS RNA binding protein. (466 aa)
	SLC5A7	Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (580 aa)
	Ckmt1a	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (417 aa)
	ITGA8	Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1066 aa)
	CLCN2	Chloride channel protein. (903 aa)
	HPCA	Hippocalcin. (193 aa)
	NTRK2	Tyrosine-protein kinase receptor. (821 aa)
	GRIA3	Glutamate ionotropic receptor AMPA type subunit 3. (899 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
	CACNA1E	Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2312 aa)
	CRHBP	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
	NTSR2	Neurotensin receptor 2; Belongs to the G-protein coupled receptor 1 family. (416 aa)
	PCSK1	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (753 aa)
	ITGA1	Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
	GRIK3	Glutamate ionotropic receptor kainate type subunit 3. (919 aa)
	UCN	Urocortin. (127 aa)
	Resp18	RESP18 domain-containing protein. (174 aa)
	SLC17A8	Solute carrier family 17 member 8. (589 aa)
	GRIK5	Glutamate ionotropic receptor kainate type subunit 5. (847 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)
	CNGA3	Cyclic nucleotide gated channel subunit alpha 3. (688 aa)
	Got2	Aminotran_1_2 domain-containing protein. (274 aa)
	ENSSTOP00000030920	Uncharacterized protein. (284 aa)
	ENSSTOP00000030697	RRM domain-containing protein. (311 aa)
	PCSK5	Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1880 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	Pde11a	Phosphodiesterase. (933 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (556 aa)
	CNGA4	Cyclic nucleotide gated channel subunit alpha 4. (530 aa)
	GLUL	Glutamine synthetase. (373 aa)
	HTR5A	5-hydroxytryptamine receptor 5A. (357 aa)
	GRIK4	Glutamate ionotropic receptor kainate type subunit 4. (947 aa)
	NTSR1	Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (418 aa)
	ENDOG	Endonuclease. (281 aa)
	Cacna1h	Uncharacterized protein. (2259 aa)
	GJC2	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (435 aa)
	BGLAP	Osteocalcin; Binds strongly to apatite and calcium. (95 aa)
	Asl	Uncharacterized protein. (464 aa)
	MAP2K4	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (360 aa)
	PNMT	Phenylethanolamine N-methyltransferase. (283 aa)
	KNG1	Kininogen 1. (651 aa)
	PGR	Progesterone receptor. (932 aa)
	PCMT1	Protein-L-isoaspartate O-methyltransferase. (286 aa)
	CHRNA10	Cholinergic receptor nicotinic alpha 10 subunit. (447 aa)
	RBFOX3	RNA binding fox-1 homolog 3. (311 aa)
	NSMF	NMDA receptor synaptonuclear signaling and neuronal migration factor. (530 aa)
	SLC1A1	Amino acid transporter. (523 aa)
	I3N8Q7_ICTTR	Uncharacterized protein. (292 aa)
	CCK	Cholecystokinin. (115 aa)
	EFNA2	Ephrin A2; Belongs to the ephrin family. (197 aa)
	LOC101969207	C-C motif chemokine. (136 aa)
	TH	Tyrosine hydroxylase. (497 aa)
	LOC101967418	Uncharacterized protein. (2364 aa)
	KCNAB1	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (385 aa)
	PPP5C	Serine/threonine-protein phosphatase. (499 aa)
	LOC101971282	RRM domain-containing protein. (452 aa)
	PAM	Peptidylglycine alpha-amidating monooxygenase. (979 aa)
	RUFY3	RUN and FYVE domain containing 3. (583 aa)
	LOC101977971	Aminotran_1_2 domain-containing protein. (393 aa)
	MCRS1	Microspherule protein 1. (462 aa)
	GRIA2	Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
	NCDN	Neurochondrin. (735 aa)
	ENO2	Enolase 2. (434 aa)
	CRHR2	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (436 aa)
	PDE9A	Phosphodiesterase. (511 aa)
	ENSSTOP00000027688	Uncharacterized protein. (316 aa)
	NPFF	Neuropeptide FF-amide peptide precursor. (109 aa)
	CACNA1A	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2092 aa)
	OPRM1	Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (326 aa)
	CAMK2B	Calcium/calmodulin dependent protein kinase II beta. (666 aa)
	PTPN5	Protein tyrosine phosphatase non-receptor type 5. (538 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASS1	ATP7A	ENSSTOP00000027442	ENSSTOP00000002370	Argininosuccinate synthase 1.	ATPase copper transporting alpha.	0.497
ASS1	Asl	ENSSTOP00000027442	ENSSTOP00000017691	Argininosuccinate synthase 1.	Uncharacterized protein.	0.999
ASS1	ENSSTOP00000029768	ENSSTOP00000027442	ENSSTOP00000029768	Argininosuccinate synthase 1.	Aminotran_1_2 domain-containing protein.	0.742
ASS1	GLUL	ENSSTOP00000027442	ENSSTOP00000013014	Argininosuccinate synthase 1.	Glutamine synthetase.	0.791
ASS1	Got2	ENSSTOP00000027442	ENSSTOP00000031640	Argininosuccinate synthase 1.	Aminotran_1_2 domain-containing protein.	0.742
ASS1	LOC101962681	ENSSTOP00000027442	ENSSTOP00000029178	Argininosuccinate synthase 1.	Aminotran_1_2 domain-containing protein.	0.742
ASS1	LOC101977971	ENSSTOP00000027442	ENSSTOP00000025592	Argininosuccinate synthase 1.	Aminotran_1_2 domain-containing protein.	0.742
ATP7A	ASS1	ENSSTOP00000002370	ENSSTOP00000027442	ATPase copper transporting alpha.	Argininosuccinate synthase 1.	0.497
Asl	ASS1	ENSSTOP00000017691	ENSSTOP00000027442	Uncharacterized protein.	Argininosuccinate synthase 1.	0.999
Asl	ENSSTOP00000029768	ENSSTOP00000017691	ENSSTOP00000029768	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.644
Asl	GLUL	ENSSTOP00000017691	ENSSTOP00000013014	Uncharacterized protein.	Glutamine synthetase.	0.482
Asl	Got2	ENSSTOP00000017691	ENSSTOP00000031640	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.644
Asl	LOC101962681	ENSSTOP00000017691	ENSSTOP00000029178	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.644
Asl	LOC101977971	ENSSTOP00000017691	ENSSTOP00000025592	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.644
CACNA1A	CACNA1E	ENSSTOP00000028203	ENSSTOP00000008403	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.	0.901
CACNA1A	CAMK2B	ENSSTOP00000028203	ENSSTOP00000000405	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Calcium/calmodulin dependent protein kinase II beta.	0.496
CACNA1A	Cacna1h	ENSSTOP00000028203	ENSSTOP00000015973	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Uncharacterized protein.	0.788
CACNA1A	LOC101967418	ENSSTOP00000028203	ENSSTOP00000022814	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Uncharacterized protein.	0.788
CACNA1E	CACNA1A	ENSSTOP00000008403	ENSSTOP00000028203	Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	0.901
CACNA1E	CAMK2B	ENSSTOP00000008403	ENSSTOP00000000405	Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.	Calcium/calmodulin dependent protein kinase II beta.	0.490