STRINGSTRING
MADD MADD KIF1A KIF1A ATP6V1G2 ATP6V1G2 PRRT1 PRRT1 SLC18A3 SLC18A3 SVOP SVOP SPHK1 SPHK1 Tmem230 Tmem230 DMXL2 DMXL2 MT3 MT3 BTBD8 BTBD8 GRIN2A GRIN2A SYT10 SYT10 SLC10A4 SLC10A4 PICALM PICALM PSEN2 PSEN2 Septin5 Septin5 Rab4b Rab4b RAB3B RAB3B Bcl2l1 Bcl2l1 SLC6A7 SLC6A7 PDE4B PDE4B SLC6A9 SLC6A9 GRIN1 GRIN1 GRIA2 GRIA2 ENSSTOP00000026182 ENSSTOP00000026182 ENSSTOP00000026508 ENSSTOP00000026508 ENSSTOP00000026642 ENSSTOP00000026642 LOC101959679 LOC101959679 OTOF OTOF DLG1 DLG1 CLTA CLTA SCAMP1 SCAMP1 PTPRS PTPRS ICA1 ICA1 ENSSTOP00000028182 ENSSTOP00000028182 Vamp3 Vamp3 RAB11B RAB11B SCAMP5 SCAMP5 SNAP47 SNAP47 MME MME SYT7 SYT7 IGF1 IGF1 ATP6V0A1 ATP6V0A1 RAB27A RAB27A MTMR2 MTMR2 RAB3IL1 RAB3IL1 Trappc4 Trappc4 SV2A SV2A APC APC ABCC8 ABCC8 ENTPD1 ENTPD1 TRPM7 TRPM7 RNF112 RNF112 SNAPIN SNAPIN GRIN2B GRIN2B PTPN5 PTPN5 SNAP91 SNAP91 SLC17A6 SLC17A6 PRRT2 PRRT2 DOC2A DOC2A GAD2 GAD2 GABBR1 GABBR1 DLG2 DLG2 RAB3A RAB3A RAB27B RAB27B SYN3 SYN3 DDC DDC CACFD1 CACFD1 SYP SYP SYT11 SYT11 GABRA2 GABRA2 RAB3C RAB3C PPT1 PPT1 Vamp2 Vamp2 SLC18A2 SLC18A2 STON2 STON2 SYNPR SYNPR CYP19A1 CYP19A1 SLC5A7 SLC5A7 SEMA4C SEMA4C Syngr2 Syngr2 MYO5A MYO5A Tprg1l Tprg1l ERC1 ERC1 CDKN2AIPNL CDKN2AIPNL STX10 STX10 SLC6A15 SLC6A15 GRIA1 GRIA1 NCSTN NCSTN SLC6A17 SLC6A17 KIRREL3 KIRREL3 STX1A STX1A MAL2 MAL2 SYT9 SYT9 RAB5B RAB5B DNAJC5 DNAJC5 AP2A2 AP2A2 SLC30A3 SLC30A3 C16orf70 C16orf70 SYN2 SYN2 SV2B SV2B SLC17A8 SLC17A8 OPRD1 OPRD1 TRIM9 TRIM9 MARCKSL1 MARCKSL1 SYNGR3 SYNGR3 RAB26 RAB26 SGTA SGTA UNC13D UNC13D SV2C SV2C KIF3C KIF3C GIPC1 GIPC1 RAB35 RAB35 MCTP1 MCTP1 VPS45 VPS45 SLC17A7 SLC17A7 Rab3ip Rab3ip LOC101970259 LOC101970259 RPH3A RPH3A ATP6V0D1 ATP6V0D1 SYNJ2 SYNJ2 SHH SHH SYNGR1 SYNGR1 KCNK9 KCNK9 WFS1 WFS1 SLC9B2 SLC9B2 UNC13C UNC13C VTI1B VTI1B STX16 STX16 SYNDIG1 SYNDIG1 SYN1 SYN1 I3MYM1_ICTTR I3MYM1_ICTTR Dmd Dmd I3N0K9_ICTTR I3N0K9_ICTTR RAB4A RAB4A LOC101967215 LOC101967215 CADM1 CADM1 PRKN PRKN RAB2A RAB2A STX12 STX12 CLTB CLTB SLC40A1 SLC40A1 WDR7 WDR7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MADDMAP kinase activating death domain. (1597 aa)
KIF1AKinesin family member 1A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1689 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
PRRT1Proline rich transmembrane protein 1. (271 aa)
SLC18A3Solute carrier family 18 member A3. (531 aa)
SVOPSV2 related protein. (527 aa)
SPHK1Sphingosine kinase 1. (385 aa)
Tmem230Uncharacterized protein. (120 aa)
DMXL2Dmx like 2. (3057 aa)
MT3Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (68 aa)
BTBD8BTB domain containing 8. (1398 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1423 aa)
SYT10Synaptotagmin 10. (523 aa)
SLC10A4Solute carrier family 10 member 4. (439 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (660 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
Septin5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (378 aa)
Rab4bUncharacterized protein. (213 aa)
RAB3BRAB3B, member RAS oncogene family. (219 aa)
Bcl2l1BH4_2 domain-containing protein. (233 aa)
SLC6A7Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (636 aa)
PDE4BPhosphodiesterase. (737 aa)
SLC6A9Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (685 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (959 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
ENSSTOP00000026182Uncharacterized protein. (109 aa)
ENSSTOP00000026508BH4_2 domain-containing protein. (224 aa)
ENSSTOP00000026642Uncharacterized protein. (98 aa)
LOC101959679Uncharacterized protein. (767 aa)
OTOFOtoferlin. (1995 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
SCAMP1Secretory carrier-associated membrane protein. (338 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1855 aa)
ICA1Islet cell autoantigen 1. (482 aa)
ENSSTOP00000028182Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (126 aa)
Vamp3V-SNARE coiled-coil homology domain-containing protein. (106 aa)
RAB11BRAB11B, member RAS oncogene family. (218 aa)
SCAMP5Secretory carrier-associated membrane protein. (235 aa)
SNAP47Synaptosome associated protein 47. (447 aa)
MMEMembrane metalloendopeptidase. (749 aa)
SYT7Synaptotagmin 7. (688 aa)
IGF1Insulin like growth factor 1. (166 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (863 aa)
RAB27ARAB27A, member RAS oncogene family. (220 aa)
MTMR2Myotubularin related protein 2. (643 aa)
RAB3IL1RAB3A interacting protein like 1. (408 aa)
Trappc4Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (194 aa)
SV2ASynaptic vesicle glycoprotein 2A. (741 aa)
APCAPC regulator of WNT signaling pathway. (2865 aa)
ABCC8ATP binding cassette subfamily C member 8. (1624 aa)
ENTPD1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (509 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1727 aa)
RNF112Ring finger protein 112. (645 aa)
SNAPINSNAP associated protein. (125 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
PTPN5Protein tyrosine phosphatase non-receptor type 5. (538 aa)
SNAP91Synaptosome associated protein 91. (902 aa)
SLC17A6Solute carrier family 17 member 6. (582 aa)
PRRT2Proline rich transmembrane protein 2. (414 aa)
DOC2ADouble C2-like domain-containing protein. (401 aa)
GAD2Glutamate decarboxylase 2. (585 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (984 aa)
DLG2Discs large MAGUK scaffold protein 2. (870 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
SYN3Synapsin III. (579 aa)
DDCDopa decarboxylase. (432 aa)
CACFD1Calcium channel flower domain containing 1. (171 aa)
SYPSynaptophysin. (313 aa)
SYT11Synaptotagmin 11. (419 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
RAB3CRAB3C, member RAS oncogene family. (227 aa)
PPT1Palmitoyl-protein thioesterase 1. (278 aa)
Vamp2V-SNARE coiled-coil homology domain-containing protein. (140 aa)
SLC18A2Solute carrier family 18 member A2. (518 aa)
STON2Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (899 aa)
SYNPRSynaptoporin. (285 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
SLC5A7Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (580 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (831 aa)
Syngr2Synaptogyrin. (223 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1845 aa)
Tprg1lHSac2 domain-containing protein. (266 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1120 aa)
CDKN2AIPNLCDKN2A interacting protein N-terminal like. (116 aa)
STX10Syntaxin 10; Belongs to the syntaxin family. (254 aa)
SLC6A15Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (732 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (837 aa)
NCSTNNicastrin. (709 aa)
SLC6A17Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (727 aa)
KIRREL3Kirre like nephrin family adhesion molecule 3. (753 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (284 aa)
MAL2Mal, T cell differentiation protein 2 (gene/pseudogene). (144 aa)
SYT9Synaptotagmin 9. (491 aa)
RAB5BRAB5B, member RAS oncogene family. (215 aa)
DNAJC5DnaJ heat shock protein family (Hsp40) member C5. (198 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (914 aa)
SLC30A3Solute carrier family 30 member 3. (388 aa)
C16orf70Chromosome 16 open reading frame 70. (428 aa)
SYN2Synapsin II. (521 aa)
SV2BSynaptic vesicle glycoprotein 2B. (683 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (372 aa)
TRIM9Tripartite motif containing 9. (788 aa)
MARCKSL1MARCKS like 1. (178 aa)
SYNGR3Synaptogyrin. (229 aa)
RAB26RAB26, member RAS oncogene family. (278 aa)
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (313 aa)
UNC13DUnc-13 homolog D. (1089 aa)
SV2CSynaptic vesicle glycoprotein 2C. (727 aa)
KIF3CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (794 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
RAB35RAB35, member RAS oncogene family. (199 aa)
MCTP1Multiple C2 and transmembrane domain containing 1. (952 aa)
VPS45Vacuolar protein sorting 45 homolog; Belongs to the STXBP/unc-18/SEC1 family. (570 aa)
SLC17A7Solute carrier family 17 member 7. (560 aa)
Rab3ipSec2p domain-containing protein. (459 aa)
LOC101970259Uncharacterized protein. (1976 aa)
RPH3ARabphilin 3A. (679 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
SYNJ2Synaptojanin 2. (1471 aa)
SHHSonic hedgehog signaling molecule. (370 aa)
SYNGR1Synaptogyrin 1. (201 aa)
KCNK9Potassium channel subfamily K member. (372 aa)
WFS1Wolframin ER transmembrane glycoprotein. (889 aa)
SLC9B2Solute carrier family 9 member B2. (509 aa)
UNC13CUnc-13 homolog C. (2117 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (232 aa)
STX16Syntaxin 16; Belongs to the syntaxin family. (327 aa)
SYNDIG1Synapse differentiation inducing 1. (258 aa)
SYN1Synapsin I. (705 aa)
I3MYM1_ICTTRUncharacterized protein. (210 aa)
DmdUncharacterized protein. (1255 aa)
I3N0K9_ICTTRUncharacterized protein. (198 aa)
RAB4ARAB4A, member RAS oncogene family. (218 aa)
LOC101967215Double C2-like domain-containing protein. (404 aa)
CADM1Cell adhesion molecule 1. (477 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (463 aa)
RAB2ARAB2A, member RAS oncogene family. (196 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (274 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (574 aa)
WDR7WD repeat domain 7. (1490 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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