STRINGSTRING
Pik3r2 Pik3r2 ZAP70 ZAP70 SOCS3 SOCS3 INPPL1 INPPL1 VAV1 VAV1 FRK FRK SHE SHE ITK ITK SH2D3C SH2D3C CRKL CRKL STAT1 STAT1 SRMS SRMS PTK6 PTK6 JAK3 JAK3 FYN FYN SH2B1 SH2B1 STAT3 STAT3 STAT5A STAT5A I3LWF9_ICTTR I3LWF9_ICTTR SHC1 SHC1 SUPT6H SUPT6H BLK BLK RASA1 RASA1 FER FER NCK2 NCK2 SH2B3 SH2B3 NCK1 NCK1 INPP5D INPP5D GRAP2 GRAP2 Chn2 Chn2 SHC4 SHC4 TYK2 TYK2 SH2D4B SH2D4B GRB7 GRB7 SOCS4 SOCS4 BTK BTK TNS4 TNS4 HCK HCK PLCG2 PLCG2 SYK SYK BMX BMX JAK2 JAK2 STAT5B STAT5B VAV3 VAV3 SH3BP2 SH3BP2 Shc2 Shc2 TNS1 TNS1 SOCS7 SOCS7 PTPN6 PTPN6 LYN LYN Pik3r3 Pik3r3 DAPP1 DAPP1 TNS2 TNS2 TEC TEC SHF SHF RIN2 RIN2 CHN1 CHN1 PIK3R1 PIK3R1 SH2B2 SH2B2 ENSSTOP00000024790 ENSSTOP00000024790 CRK CRK GRB10 GRB10 STAP1 STAP1 ABL1 ABL1 STAP2 STAP2 VAV2 VAV2 SH2D2A SH2D2A Shb Shb SOCS5 SOCS5 GRAP GRAP CISH CISH SHD SHD SOCS1 SOCS1 ABL2 ABL2 CSK CSK PTPN11 PTPN11 JAK1 JAK1 CLNK CLNK STAT4 STAT4 TXK TXK FGR FGR RIN1 RIN1 SH2D4A SH2D4A SRC SRC LCP2 LCP2 STAT2 STAT2 TNS3 TNS3 GRB14 GRB14 SH2D5 SH2D5 FES FES SH2D1A SH2D1A SLA2 SLA2 STAT6 STAT6 BLNK BLNK GRB2 GRB2 SOCS2 SOCS2 SLA SLA LCK LCK MATK MATK PLCG1 PLCG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Pik3r2Uncharacterized protein. (724 aa)
ZAP70Tyrosine-protein kinase. (608 aa)
SOCS3Suppressor of cytokine signaling 3. (227 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
VAV1Vav guanine nucleotide exchange factor 1. (822 aa)
FRKTyrosine-protein kinase. (511 aa)
SHESrc homology 2 domain containing E. (430 aa)
ITKTyrosine-protein kinase. (620 aa)
SH2D3CSH2 domain containing 3C. (858 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
SRMSTyrosine-protein kinase. (534 aa)
PTK6Tyrosine-protein kinase. (450 aa)
JAK3Tyrosine-protein kinase. (1042 aa)
FYNTyrosine-protein kinase. (537 aa)
SH2B1SH2B adaptor protein 1. (757 aa)
STAT3Signal transducer and activator of transcription. (748 aa)
STAT5ASignal transducer and activator of transcription. (773 aa)
I3LWF9_ICTTRSH2 domain-containing protein. (118 aa)
SHC1SHC adaptor protein 1. (583 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
BLKTyrosine-protein kinase. (499 aa)
RASA1RAS p21 protein activator 1. (1030 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
NCK2Cytoplasmic protein. (380 aa)
SH2B3SH2B adaptor protein 3. (429 aa)
NCK1Cytoplasmic protein. (377 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1213 aa)
GRAP2GRB2 related adaptor protein 2. (324 aa)
Chn2Chimaerin; GTPase-activating protein for p21-rac. (468 aa)
SHC4SHC adaptor protein 4. (630 aa)
TYK2Tyrosine-protein kinase. (1194 aa)
SH2D4BSH2 domain containing 4B. (431 aa)
GRB7Growth factor receptor bound protein 7. (531 aa)
SOCS4Suppressor of cytokine signaling 4. (439 aa)
BTKTyrosine-protein kinase. (659 aa)
TNS4Tensin 4. (697 aa)
HCKTyrosine-protein kinase. (502 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
SYKTyrosine-protein kinase. (626 aa)
BMXTyrosine-protein kinase. (655 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
STAT5BSignal transducer and activator of transcription. (765 aa)
VAV3Vav guanine nucleotide exchange factor 3. (847 aa)
SH3BP2SH3 domain binding protein 2. (606 aa)
Shc2Uncharacterized protein. (581 aa)
TNS1Tensin 1. (1867 aa)
SOCS7Suppressor of cytokine signaling 7. (578 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
LYNTyrosine-protein kinase. (512 aa)
Pik3r3Uncharacterized protein. (461 aa)
DAPP1Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (280 aa)
TNS2Tensin 2. (1404 aa)
TECTyrosine-protein kinase. (630 aa)
SHFSrc homology 2 domain containing F. (321 aa)
RIN2Ras and Rab interactor 2. (899 aa)
CHN1Chimaerin; GTPase-activating protein for p21-rac. (459 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
SH2B2SH2B adaptor protein 2. (636 aa)
ENSSTOP00000024790SH2 domain-containing protein. (176 aa)
CRKCRK proto-oncogene, adaptor protein. (305 aa)
GRB10Growth factor receptor bound protein 10. (576 aa)
STAP1Signal transducing adaptor family member 1. (297 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
STAP2Signal transducing adaptor family member 2. (409 aa)
VAV2Vav guanine nucleotide exchange factor 2. (745 aa)
SH2D2ASH2 domain containing 2A. (349 aa)
ShbSH2 domain-containing protein. (495 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
GRAPUncharacterized protein. (157 aa)
CISHCytokine inducible SH2 containing protein. (257 aa)
SHDSrc homology 2 domain containing transforming protein D. (341 aa)
SOCS1Suppressor of cytokine signaling 1. (211 aa)
ABL2Tyrosine-protein kinase. (1142 aa)
CSKTyrosine-protein kinase. (450 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
JAK1Tyrosine-protein kinase. (1142 aa)
CLNKCytokine dependent hematopoietic cell linker. (423 aa)
STAT4Signal transducer and activator of transcription. (758 aa)
TXKTyrosine-protein kinase. (526 aa)
FGRTyrosine-protein kinase. (527 aa)
RIN1Ras and Rab interactor 1. (751 aa)
SH2D4ASH2 domain containing 4A. (451 aa)
SRCTyrosine-protein kinase. (541 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
STAT2Signal transducer and activator of transcription. (805 aa)
TNS3Tensin 3. (1392 aa)
GRB14Growth factor receptor bound protein 14. (540 aa)
SH2D5SH2 domain containing 5. (429 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (126 aa)
SLA2Src like adaptor 2. (268 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
BLNKB cell linker. (456 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
SOCS2Suppressor of cytokine signaling 2. (159 aa)
SLASrc like adaptor. (276 aa)
LCKTyrosine-protein kinase. (521 aa)
MATKTyrosine-protein kinase. (466 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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