STRINGSTRING
XRCC1 XRCC1 TP53BP1 TP53BP1 LIG3 LIG3 MCPH1 MCPH1 POLM POLM BARD1 BARD1 Brca1 Brca1 DBF4 DBF4 TOPBP1 TOPBP1 LIG4 LIG4 TERF2IP TERF2IP RFC1 RFC1 MDC1 MDC1 KIF24 KIF24 PARP1 PARP1 REV1 REV1 SLF1 SLF1 PAXIP1 PAXIP1 PES1 PES1 DNTT DNTT CTDP1 CTDP1 POLL POLL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
XRCC1X-ray repair cross complementing 1. (632 aa)
TP53BP1Tumor protein p53 binding protein 1. (1968 aa)
LIG3DNA ligase. (1013 aa)
MCPH1Microcephalin 1. (807 aa)
POLMDNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (494 aa)
BARD1BRCA1 associated RING domain 1. (776 aa)
Brca1Uncharacterized protein. (353 aa)
DBF4DBF4 zinc finger. (570 aa)
TOPBP1DNA topoisomerase II binding protein 1. (1527 aa)
LIG4DNA ligase. (911 aa)
TERF2IPTERF2 interacting protein. (396 aa)
RFC1Replication factor C subunit 1. (1118 aa)
MDC1Mediator of DNA damage checkpoint 1. (1845 aa)
KIF24Kinesin family member 24; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1344 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
REV1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1246 aa)
SLF1SMC5-SMC6 complex localization factor 1. (1057 aa)
PAXIP1PAX interacting protein 1. (1032 aa)
PES1Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (585 aa)
DNTTDNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (467 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (884 aa)
POLLDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (575 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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