STRINGSTRING
TMPRSS11D TMPRSS11D LOC101965973 LOC101965973 PAMR1 PAMR1 Klk8 Klk8 CTRL CTRL KLK4 KLK4 C1R C1R HABP2 HABP2 LOC101960700 LOC101960700 HGF HGF LOC101966270 LOC101966270 TMPRSS4 TMPRSS4 PRSS54 PRSS54 LOC101964433 LOC101964433 KLK14 KLK14 I3M4Y2_ICTTR I3M4Y2_ICTTR F2 F2 PRSS58 PRSS58 KLK6 KLK6 PRSS33 PRSS33 PRSS27 PRSS27 PRSS23 PRSS23 TMPRSS13 TMPRSS13 LOC101960778 LOC101960778 CTSG CTSG I3MBK1_ICTTR I3MBK1_ICTTR PRSS57 PRSS57 TMPRSS5 TMPRSS5 TMPRSS11F TMPRSS11F CELA1 CELA1 PLAT PLAT KLKB1 KLKB1 F11 F11 ST14 ST14 MASP1 MASP1 LOC101959085 LOC101959085 OVCH2 OVCH2 GZMA GZMA F9 F9 LOC101959946 LOC101959946 TMPRSS15 TMPRSS15 PRSS55 PRSS55 PROC PROC PRSS48 PRSS48 TMPRSS2 TMPRSS2 KLK5 KLK5 Cfi Cfi LOC101959666 LOC101959666 LOC101974544 LOC101974544 MST1 MST1 PRSS37 PRSS37 Cfb Cfb HTRA4 HTRA4 C1S C1S GZMK GZMK TMPRSS11A TMPRSS11A Klk1 Klk1 Prss43p Prss43p TYSND1 TYSND1 Acr Acr HTRA3 HTRA3 PRSS38 PRSS38 PRSS22 PRSS22 LOC101976500 LOC101976500 LOC101977084 LOC101977084 LOC101968389 LOC101968389 HPN HPN I3MZ36_ICTTR I3MZ36_ICTTR LOC101961680 LOC101961680 Klk9 Klk9 CFD CFD LOC101965676 LOC101965676 TMPRSS11E TMPRSS11E LOC101957774 LOC101957774 KLK12 KLK12 LOC101973046 LOC101973046 TMPRSS9 TMPRSS9 LOC101971243 LOC101971243 HGFAC HGFAC LOC101976153 LOC101976153 LOC101977364 LOC101977364 LOC101978189 LOC101978189 F10 F10 TMPRSS7 TMPRSS7 Prss46p Prss46p CMA1 CMA1 LOC101964582 LOC101964582 LOC101960226 LOC101960226 F7 F7 FAM111A FAM111A ELANE ELANE LOC101968603 LOC101968603 KLK10 KLK10 I3NCB9_ICTTR I3NCB9_ICTTR LOC101966300 LOC101966300 KLK15 KLK15 MASP2 MASP2 TMPRSS3 TMPRSS3 KLK7 KLK7 TMPRSS6 TMPRSS6 LOC101966003 LOC101966003 PLG PLG LOC101964875 LOC101964875 LOC101975297 LOC101975297 LOC101958816 LOC101958816 TMPRSS12 TMPRSS12 I3NHA7_ICTTR I3NHA7_ICTTR HTRA1 HTRA1 LOC101977635 LOC101977635 LOC101966592 LOC101966592 PRSS36 PRSS36 ENSSTOP00000026488 ENSSTOP00000026488 PRSS8 PRSS8 ENSSTOP00000027524 ENSSTOP00000027524 PRSS35 PRSS35 PRSS53 PRSS53 Prss50 Prss50 PRSS56 PRSS56 HTRA2 HTRA2 KLK11 KLK11 C2 C2 Ctrc Ctrc LOC101968019 LOC101968019 CORIN CORIN PLAU PLAU
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMPRSS11DTransmembrane protease serine; Belongs to the peptidase S1 family. (419 aa)
LOC101965973Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (279 aa)
PAMR1Peptidase domain containing associated with muscle regeneration 1; Belongs to the peptidase S1 family. (720 aa)
Klk8Peptidase S1 domain-containing protein. (139 aa)
CTRLChymotrypsin like; Belongs to the peptidase S1 family. (264 aa)
KLK4Kallikrein related peptidase 4; Belongs to the peptidase S1 family. (255 aa)
C1RComplement C1r; Belongs to the peptidase S1 family. (705 aa)
HABP2Hyaluronan binding protein 2. (536 aa)
LOC101960700Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (347 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa)
LOC101966270Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (275 aa)
TMPRSS4Transmembrane serine protease 4; Belongs to the peptidase S1 family. (402 aa)
PRSS54Serine protease 54. (373 aa)
LOC101964433Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (263 aa)
KLK14Kallikrein related peptidase 14; Belongs to the peptidase S1 family. (251 aa)
I3M4Y2_ICTTRPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (361 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
PRSS58Serine protease 58; Belongs to the peptidase S1 family. (241 aa)
KLK6Kallikrein related peptidase 6; Belongs to the peptidase S1 family. (247 aa)
PRSS33Serine protease 33; Belongs to the peptidase S1 family. (286 aa)
PRSS27Serine protease 27; Belongs to the peptidase S1 family. (324 aa)
PRSS23Serine protease 23. (382 aa)
TMPRSS13Transmembrane serine protease 13; Belongs to the peptidase S1 family. (552 aa)
LOC101960778Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (262 aa)
I3MBK1_ICTTRPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (299 aa)
PRSS57Serine protease 57; Belongs to the peptidase S1 family. (348 aa)
TMPRSS5Transmembrane serine protease 5; Belongs to the peptidase S1 family. (465 aa)
TMPRSS11FTransmembrane protease serine; Belongs to the peptidase S1 family. (438 aa)
CELA1Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (266 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (560 aa)
KLKB1Kallikrein B1; Belongs to the peptidase S1 family. (637 aa)
F11Coagulation factor XI; Belongs to the peptidase S1 family. (617 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa)
MASP1Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (733 aa)
LOC101959085Cytochrome c oxidase assembly homolog COX15. (413 aa)
OVCH2Ovochymase 2 (gene/pseudogene); Belongs to the peptidase S1 family. (621 aa)
GZMAGranzyme A; Belongs to the peptidase S1 family. (262 aa)
F9Coagulation factor IX. (463 aa)
LOC101959946Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (315 aa)
TMPRSS15Transmembrane serine protease 15; Belongs to the peptidase S1 family. (1019 aa)
PRSS55Serine protease 55; Belongs to the peptidase S1 family. (290 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa. (460 aa)
PRSS48Serine protease 48; Belongs to the peptidase S1 family. (314 aa)
TMPRSS2Transmembrane serine protease 2; Belongs to the peptidase S1 family. (531 aa)
KLK5Kallikrein related peptidase 5; Belongs to the peptidase S1 family. (293 aa)
CfiUncharacterized protein; Belongs to the peptidase S1 family. (555 aa)
LOC101959666Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (261 aa)
LOC101974544Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (253 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (715 aa)
PRSS37Serine protease 37. (233 aa)
CfbUncharacterized protein; Belongs to the peptidase S1 family. (765 aa)
HTRA4HtrA serine peptidase 4. (482 aa)
C1SComplement C1s; Belongs to the peptidase S1 family. (695 aa)
GZMKGranzyme K; Belongs to the peptidase S1 family. (263 aa)
TMPRSS11ATransmembrane serine protease 11A; Belongs to the peptidase S1 family. (358 aa)
Klk1Kallikrein 1; Belongs to the peptidase S1 family. (261 aa)
Prss43pPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (367 aa)
TYSND1Trypsin domain containing 1. (565 aa)
AcrPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (271 aa)
HTRA3HtrA serine peptidase 3. (249 aa)
PRSS38Serine protease 38; Belongs to the peptidase S1 family. (329 aa)
PRSS22Serine protease 22; Belongs to the peptidase S1 family. (318 aa)
LOC101976500Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. (347 aa)
LOC101977084Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (244 aa)
LOC101968389Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (320 aa)
HPNHepsin; Belongs to the peptidase S1 family. (417 aa)
I3MZ36_ICTTRPeptidase S1 domain-containing protein. (362 aa)
LOC101961680Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (258 aa)
Klk9Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (247 aa)
CFDComplement factor D; Belongs to the peptidase S1 family. (258 aa)
LOC101965676Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (283 aa)
TMPRSS11ETransmembrane protease serine; Belongs to the peptidase S1 family. (422 aa)
LOC101957774Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (286 aa)
KLK12Kallikrein related peptidase 12; Belongs to the peptidase S1 family. (248 aa)
LOC101973046Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (252 aa)
TMPRSS9Transmembrane serine protease 9; Belongs to the peptidase S1 family. (1070 aa)
LOC101971243Transmembrane protease serine; Belongs to the peptidase S1 family. (416 aa)
HGFACHGF activator. (653 aa)
LOC101976153Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (252 aa)
LOC101977364Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (255 aa)
LOC101978189Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (252 aa)
F10Coagulation factor X. (483 aa)
TMPRSS7Transmembrane serine protease 7; Belongs to the peptidase S1 family. (754 aa)
Prss46pPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (300 aa)
CMA1Chymase 1; Belongs to the peptidase S1 family. (212 aa)
LOC101964582Transmembrane protease serine; Belongs to the peptidase S1 family. (417 aa)
LOC101960226Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (316 aa)
F7Coagulation factor VII; Belongs to the peptidase S1 family. (375 aa)
FAM111AFamily with sequence similarity 111 member A. (613 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (266 aa)
LOC101968603Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (180 aa)
KLK10Kallikrein related peptidase 10; Belongs to the peptidase S1 family. (248 aa)
I3NCB9_ICTTRPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (277 aa)
LOC101966300Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
KLK15Kallikrein related peptidase 15; Belongs to the peptidase S1 family. (255 aa)
MASP2Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (690 aa)
TMPRSS3Transmembrane serine protease 3; Belongs to the peptidase S1 family. (453 aa)
KLK7Kallikrein related peptidase 7; Belongs to the peptidase S1 family. (249 aa)
TMPRSS6Transmembrane serine protease 6; Belongs to the peptidase S1 family. (763 aa)
LOC101966003Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (247 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (794 aa)
LOC101964875Transmembrane protease serine; Belongs to the peptidase S1 family. (432 aa)
LOC101975297Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (267 aa)
LOC101958816Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (269 aa)
TMPRSS12Transmembrane serine protease 12; Belongs to the peptidase S1 family. (349 aa)
I3NHA7_ICTTRPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (376 aa)
HTRA1HtrA serine peptidase 1. (424 aa)
LOC101977635Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (255 aa)
LOC101966592Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
PRSS36Polyserase-2; Serine protease. Has a preference for substrates with an Arg instead of a Lys residue in position P1. (849 aa)
ENSSTOP00000026488Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (263 aa)
PRSS8Serine protease 8; Belongs to the peptidase S1 family. (342 aa)
ENSSTOP00000027524Peptidase S1 domain-containing protein. (141 aa)
PRSS35Serine protease 35. (480 aa)
PRSS53Serine protease 53; Belongs to the peptidase S1 family. (553 aa)
Prss50Peptidase S1 domain-containing protein. (403 aa)
PRSS56Serine protease 56; Belongs to the peptidase S1 family. (637 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
KLK11Kallikrein related peptidase 11; Belongs to the peptidase S1 family. (282 aa)
C2Complement C2; Belongs to the peptidase S1 family. (770 aa)
CtrcPeptidase S1 domain-containing protein. (152 aa)
LOC101968019Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (253 aa)
CORINCorin, serine peptidase. (1113 aa)
PLAUPlasminogen activator, urokinase. (424 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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