133 items (Ictidomys tridecemlineatus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	POC1B	POC1 centriolar protein B. (473 aa)
	WDR12	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (423 aa)
	Traf7	Uncharacterized protein. (670 aa)
	GEMIN5	Gem nuclear organelle associated protein 5. (1507 aa)
	PRPF19	Pre-mRNA processing factor 19. (512 aa)
	BOP1	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (743 aa)
	WDR17	WD repeat domain 17. (1313 aa)
	SMU1	SMU1 DNA replication regulator and spliceosomal factor. (513 aa)
	WDR5	WD repeat domain 5. (384 aa)
	BRWD3	Bromodomain and WD repeat domain containing 3. (1798 aa)
	UTP18	UTP18 small subunit processome component. (555 aa)
	PEX7	Peroxisomal biogenesis factor 7. (318 aa)
	MLST8	MTOR associated protein, LST8 homolog. (326 aa)
	EIF3I	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (325 aa)
	WDR90	WD repeat domain 90. (1848 aa)
	CORO6	Coronin; Belongs to the WD repeat coronin family. (472 aa)
	FZR1	Fizzy and cell division cycle 20 related 1. (493 aa)
	STRN3	Striatin 3. (797 aa)
	ATG16L1	Autophagy related 16 like 1. (624 aa)
	WSB1	WD repeat and SOCS box containing 1. (421 aa)
	FBXW2	F-box and WD repeat domain containing 2. (454 aa)
	TLE4	TLE family member 4, transcriptional corepressor. (773 aa)
	PRPF4	Pre-mRNA processing factor 4. (521 aa)
	TLE1	TLE family member 1, transcriptional corepressor. (803 aa)
	COPA	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1221 aa)
	POC1A	POC1 centriolar protein A. (407 aa)
	WDR59	WD repeat domain 59. (916 aa)
	THOC6	THO complex 6. (341 aa)
	SCAP	SREBF chaperone. (1322 aa)
	CSTF1	Cleavage stimulation factor subunit 1. (431 aa)
	PAK1IP1	PAK1 interacting protein 1. (360 aa)
	KATNB1	Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (655 aa)
	BRWD1	Bromodomain and WD repeat domain containing 1. (2200 aa)
	FBXW11	F-box and WD repeat domain containing 11. (553 aa)
	DCAF7	DDB1 and CUL4 associated factor 7. (342 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
	PHIP	Pleckstrin homology domain interacting protein. (1777 aa)
	LOC101964060	Uncharacterized protein. (757 aa)
	AMBRA1	Autophagy and beclin 1 regulator 1. (1240 aa)
	APAF1	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1247 aa)
	WDR7	WD repeat domain 7. (1490 aa)
	WDR47	WD repeat domain 47. (921 aa)
	WDR77	WD repeat domain 77. (342 aa)
	WDR53	WD repeat domain 53. (358 aa)
	WDHD1	WD repeat and HMG-box DNA binding protein 1. (1106 aa)
	TAF5L	TATA-box binding protein associated factor 5 like. (591 aa)
	WDR41	WD repeat domain 41. (461 aa)
	PWP1	PWP1 homolog, endonuclein. (500 aa)
	WDR18	WD repeat domain 18. (432 aa)
	UTP15	UTP15 small subunit processome component. (527 aa)
	WDR48	WD repeat domain 48. (677 aa)
	FBXW7	F-box and WD repeat domain containing 7. (713 aa)
	Wdr86	WD_REPEATS_REGION domain-containing protein. (339 aa)
	EML5	EMAP like 5. (1969 aa)
	WDR55	WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (382 aa)
	GRWD1	Glutamate rich WD repeat containing 1. (445 aa)
	STRN4	Striatin 4. (666 aa)
	WDR5B	WD repeat domain 5B. (333 aa)
	DAW1	Dynein assembly factor with WD repeats 1. (415 aa)
	GNB2	G protein subunit beta 2. (371 aa)
	CIAO1	Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. (339 aa)
	HERC1	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4862 aa)
	CORO2B	Coronin; Belongs to the WD repeat coronin family. (475 aa)
	LYST	Lysosomal trafficking regulator. (3799 aa)
	CORO1B	Coronin; Belongs to the WD repeat coronin family. (486 aa)
	GNB3	G protein subunit beta 3. (340 aa)
	WDR72	WD repeat domain 72. (1113 aa)
	DPH7	Diphthamide biosynthesis 7. (447 aa)
	WDR36	WD repeat domain 36. (1014 aa)
	NWD1	NACHT and WD repeat domain containing 1. (1243 aa)
	TAF5	TATA-box binding protein associated factor 5. (787 aa)
	WDR37	WD repeat domain 37. (496 aa)
	Tbl1x	Uncharacterized protein. (530 aa)
	TBL1XR1	Transducin beta like 1 X-linked receptor 1. (514 aa)
	Pwp2	Uncharacterized protein. (923 aa)
	GNB5	G protein subunit beta 5. (386 aa)
	STRN	Striatin. (738 aa)
	DTL	Denticleless E3 ubiquitin protein ligase homolog. (730 aa)
	NUP43	Nucleoporin 43. (380 aa)
	TBL3	Transducin beta like 3. (800 aa)
	Aamp	WD_REPEATS_REGION domain-containing protein. (435 aa)
	RBBP4	RB binding protein 4, chromatin remodeling factor. (425 aa)
	KIF21B	Kinesin family member 21B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1637 aa)
	DENND3	DENN domain containing 3. (1284 aa)
	KIF21A	Kinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1670 aa)
	CORO1C	Coronin; Belongs to the WD repeat coronin family. (474 aa)
	GTF3C2	General transcription factor IIIC subunit 2. (909 aa)
	TLE2	TLE family member 2, transcriptional corepressor. (749 aa)
	TBL2	Transducin beta like 2. (443 aa)
	WDFY4	WDFY family member 4. (3134 aa)
	GNB1	G protein subunit beta 1. (340 aa)
	PLRG1	Pleiotropic regulator 1. (515 aa)
	STXBP5L	Syntaxin binding protein 5 like. (1186 aa)
	WDFY3	WD repeat and FYVE domain containing 3. (2987 aa)
	WDSUB1	WD repeat, sterile alpha motif and U-box domain containing 1. (476 aa)
	Wdfy1	Uncharacterized protein. (364 aa)
	SEC31B	SEC31 homolog B, COPII coat complex component. (1168 aa)
	COP1	COP1 E3 ubiquitin ligase. (641 aa)
	CORO1A	Coronin; Belongs to the WD repeat coronin family. (461 aa)
	DCAF13	DDB1 and CUL4 associated factor 13. (445 aa)
	WDR38	WD repeat domain 38. (294 aa)
	WDR61	WD repeat domain 61. (305 aa)
	DDB2	Damage specific DNA binding protein 2. (430 aa)
	RACK1	Receptor for activated C kinase 1. (317 aa)
	WDR11	WD repeat domain 11. (1224 aa)
	FBXW9	F-box and WD repeat domain containing 9. (462 aa)
	DCAF12	DDB1 and CUL4 associated factor 12. (453 aa)
	WDR83	WD repeat domain 83. (315 aa)
	EIPR1	EARP complex and GARP complex interacting protein 1. (387 aa)
	LRWD1	Leucine rich repeats and WD repeat domain containing 1. (649 aa)
	NLE1	Notchless homolog 1. (485 aa)
	ERCC8	ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa)
	GNB4	G protein subunit beta 4. (340 aa)
	EED	Embryonic ectoderm development. (441 aa)
	WDR1	WD repeat domain 1. (618 aa)
	AAAS	Aladin WD repeat nucleoporin. (545 aa)
	CORO2A	Coronin; Belongs to the WD repeat coronin family. (542 aa)
	WDR24	WD repeat domain 24. (789 aa)
	WSB2	WD repeat and SOCS box containing 2. (403 aa)
	ATG16L2	Autophagy related 16 like 2. (620 aa)
	SNRNP40	Small nuclear ribonucleoprotein U5 subunit 40. (358 aa)
	WDR3	WD repeat domain 3. (943 aa)
	WDFY2	WD repeat and FYVE domain containing 2. (400 aa)
	RBBP7	RB binding protein 7, chromatin remodeling factor. (425 aa)
	RRP9	Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein. (475 aa)
	PAFAH1B1	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (411 aa)
	NUP37	Nucleoporin 37. (326 aa)
	CHAF1B	Chromatin assembly factor 1 subunit B. (567 aa)
	WDR31	WD repeat domain 31. (367 aa)
	TLE3	TLE family member 3, transcriptional corepressor. (768 aa)
	LOC101973190	Coronin; Belongs to the WD repeat coronin family. (923 aa)
	RAE1	Ribonucleic acid export 1. (368 aa)
	CFAP52	Cilia and flagella associated protein 52. (620 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAAS	GEMIN5	ENSSTOP00000003920	ENSSTOP00000031448	Aladin WD repeat nucleoporin.	Gem nuclear organelle associated protein 5.	0.590
AAAS	NUP37	ENSSTOP00000003920	ENSSTOP00000001669	Aladin WD repeat nucleoporin.	Nucleoporin 37.	0.952
AAAS	NUP43	ENSSTOP00000003920	ENSSTOP00000012057	Aladin WD repeat nucleoporin.	Nucleoporin 43.	0.988
AAAS	RAE1	ENSSTOP00000003920	ENSSTOP00000000330	Aladin WD repeat nucleoporin.	Ribonucleic acid export 1.	0.960
AMBRA1	APAF1	ENSSTOP00000020016	ENSSTOP00000019918	Autophagy and beclin 1 regulator 1.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.438
AMBRA1	ATG16L1	ENSSTOP00000020016	ENSSTOP00000025869	Autophagy and beclin 1 regulator 1.	Autophagy related 16 like 1.	0.459
AMBRA1	COP1	ENSSTOP00000020016	ENSSTOP00000007580	Autophagy and beclin 1 regulator 1.	COP1 E3 ubiquitin ligase.	0.477
AMBRA1	DCAF13	ENSSTOP00000020016	ENSSTOP00000007182	Autophagy and beclin 1 regulator 1.	DDB1 and CUL4 associated factor 13.	0.543
AMBRA1	DCAF7	ENSSTOP00000020016	ENSSTOP00000021938	Autophagy and beclin 1 regulator 1.	DDB1 and CUL4 associated factor 7.	0.626
AMBRA1	DDB2	ENSSTOP00000020016	ENSSTOP00000006764	Autophagy and beclin 1 regulator 1.	Damage specific DNA binding protein 2.	0.478
AMBRA1	DTL	ENSSTOP00000020016	ENSSTOP00000012151	Autophagy and beclin 1 regulator 1.	Denticleless E3 ubiquitin protein ligase homolog.	0.530
AMBRA1	ERCC8	ENSSTOP00000020016	ENSSTOP00000004762	Autophagy and beclin 1 regulator 1.	ERCC excision repair 8, CSA ubiquitin ligase complex subunit.	0.486
AMBRA1	NUP43	ENSSTOP00000020016	ENSSTOP00000012057	Autophagy and beclin 1 regulator 1.	Nucleoporin 43.	0.538
APAF1	AMBRA1	ENSSTOP00000019918	ENSSTOP00000020016	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Autophagy and beclin 1 regulator 1.	0.438
APAF1	BRWD1	ENSSTOP00000019918	ENSSTOP00000022603	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Bromodomain and WD repeat domain containing 1.	0.495
APAF1	BRWD3	ENSSTOP00000019918	ENSSTOP00000030840	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Bromodomain and WD repeat domain containing 3.	0.495
APAF1	CFAP52	ENSSTOP00000019918	ENSSTOP00000000110	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Cilia and flagella associated protein 52.	0.438
APAF1	COP1	ENSSTOP00000019918	ENSSTOP00000007580	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	COP1 E3 ubiquitin ligase.	0.402
APAF1	DCAF7	ENSSTOP00000019918	ENSSTOP00000021938	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	DDB1 and CUL4 associated factor 7.	0.592
APAF1	DDB2	ENSSTOP00000019918	ENSSTOP00000006764	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Damage specific DNA binding protein 2.	0.555