STRINGSTRING
ATAD5 ATAD5 POLE2 POLE2 RFC1 RFC1 SPRTN SPRTN TRIM25 TRIM25 Rps27a Rps27a UBE2L6 UBE2L6 MAD2L2 MAD2L2 POLH POLH POLD1 POLD1 Rfc4 Rfc4 TRIM47 TRIM47 TRIM65 TRIM65 UBA7 UBA7 REV1 REV1 RCBTB2 RCBTB2 VCP VCP USP10 USP10 Pold4 Pold4 SPATA5 SPATA5 I3MU87_ICTTR I3MU87_ICTTR I3MUA8_ICTTR I3MUA8_ICTTR POLE POLE RPA1 RPA1 NPLOC4 NPLOC4 Pclaf Pclaf RFC2 RFC2 LOC101955511 LOC101955511 LOC101966763 LOC101966763 Pole3 Pole3 MEIOB MEIOB Pcna Pcna USP31 USP31 SPATA5L1 SPATA5L1 Rfc5 Rfc5 ENSSTOP00000025372 ENSSTOP00000025372 REV3L REV3L LOC101973038 LOC101973038 POLE4 POLE4 RCBTB1 RCBTB1 RPA3 RPA3 Polk Polk ENSSTOP00000028703 ENSSTOP00000028703 RCHY1 RCHY1 ENSSTOP00000029771 ENSSTOP00000029771 ENSSTOP00000029795 ENSSTOP00000029795 ENSSTOP00000031366 ENSSTOP00000031366 USP43 USP43 RFC3 RFC3 Pold3 Pold3 POLD2 POLD2 UFD1 UFD1 POLI POLI RPA2 RPA2 UBA52 UBA52
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATAD5ATPase family AAA domain containing 5. (1897 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (504 aa)
RFC1Replication factor C subunit 1. (1118 aa)
SPRTNSprT-like N-terminal domain. (489 aa)
TRIM25Tripartite motif containing 25. (644 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
UBE2L6Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
POLHDNA polymerase eta. (714 aa)
POLD1DNA polymerase. (1106 aa)
Rfc4AAA domain-containing protein. (364 aa)
TRIM47Tripartite motif containing 47. (544 aa)
TRIM65Tripartite motif containing 65. (443 aa)
UBA7Ubiquitin like modifier activating enzyme 7. (999 aa)
REV1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1246 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (551 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
USP10Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (788 aa)
Pold4Uncharacterized protein. (107 aa)
SPATA5Spermatogenesis associated 5. (839 aa)
I3MU87_ICTTRProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (250 aa)
I3MUA8_ICTTRAAA domain-containing protein. (312 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2282 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (592 aa)
NPLOC4NPL4 homolog, ubiquitin recognition factor. (603 aa)
PclafPAF domain-containing protein. (111 aa)
RFC2Replication factor C subunit 2. (321 aa)
LOC101955511Uncharacterized protein. (626 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
Pole3CBFD_NFYB_HMF domain-containing protein. (147 aa)
MEIOBMeiosis specific with OB-fold. (471 aa)
PcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
USP31Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1140 aa)
SPATA5L1Spermatogenesis associated 5 like 1. (789 aa)
Rfc5AAA domain-containing protein. (340 aa)
ENSSTOP00000025372CBFD_NFYB_HMF domain-containing protein. (134 aa)
REV3LREV3 like, DNA directed polymerase zeta catalytic subunit. (3127 aa)
LOC101973038UmuC domain-containing protein. (265 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (115 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
RPA3Replication protein A3. (121 aa)
PolkUmuC domain-containing protein. (541 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
RCHY1Ring finger and CHY zinc finger domain containing 1. (261 aa)
ENSSTOP00000029771AAA domain-containing protein. (336 aa)
ENSSTOP00000029795PAF domain-containing protein. (104 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
USP43Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family. (1131 aa)
RFC3Replication factor C subunit 3. (339 aa)
Pold3Uncharacterized protein. (467 aa)
POLD2DNA polymerase delta 2, accessory subunit. (469 aa)
UFD1Ubiquitin recognition factor in ER associated degradation 1. (307 aa)
POLIDNA polymerase iota. (720 aa)
RPA2Replication protein A2. (271 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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