STRINGSTRING
RPA2 RPA2 RFC3 RFC3 Pold3 Pold3 POLD2 POLD2 CUL4A CUL4A UBA52 UBA52 RAD18 RAD18 USP1 USP1 POLE2 POLE2 RFC1 RFC1 DDB1 DDB1 Rps27a Rps27a POLD1 POLD1 Rfc4 Rfc4 DTL DTL RCBTB2 RCBTB2 Rbx1 Rbx1 Pold4 Pold4 ATAD5 ATAD5 I3MU87_ICTTR I3MU87_ICTTR I3MUA8_ICTTR I3MUA8_ICTTR POLE POLE RPA1 RPA1 WDR48 WDR48 CUL4B CUL4B RFC2 RFC2 I3N110_ICTTR I3N110_ICTTR LOC101966763 LOC101966763 Pole3 Pole3 MEIOB MEIOB Pcna Pcna Rfc5 Rfc5 ENSSTOP00000025372 ENSSTOP00000025372 POLE4 POLE4 RCBTB1 RCBTB1 RPA3 RPA3 ENSSTOP00000028703 ENSSTOP00000028703 ENSSTOP00000028717 ENSSTOP00000028717 ENSSTOP00000029771 ENSSTOP00000029771 ENSSTOP00000031366 ENSSTOP00000031366
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPA2Replication protein A2. (271 aa)
RFC3Replication factor C subunit 3. (339 aa)
Pold3Uncharacterized protein. (467 aa)
POLD2DNA polymerase delta 2, accessory subunit. (469 aa)
CUL4ACullin 4A; Belongs to the cullin family. (671 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
RAD18Uncharacterized protein. (310 aa)
USP1Ubiquitin specific peptidase 1; Belongs to the peptidase C19 family. (719 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (504 aa)
RFC1Replication factor C subunit 1. (1118 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
POLD1DNA polymerase. (1106 aa)
Rfc4AAA domain-containing protein. (364 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (730 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (551 aa)
Rbx1RING-type domain-containing protein. (108 aa)
Pold4Uncharacterized protein. (107 aa)
ATAD5ATPase family AAA domain containing 5. (1897 aa)
I3MU87_ICTTRProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (250 aa)
I3MUA8_ICTTRAAA domain-containing protein. (312 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2282 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (592 aa)
WDR48WD repeat domain 48. (677 aa)
CUL4BCullin 4B; Belongs to the cullin family. (970 aa)
RFC2Replication factor C subunit 2. (321 aa)
I3N110_ICTTRRING-type domain-containing protein. (147 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
Pole3CBFD_NFYB_HMF domain-containing protein. (147 aa)
MEIOBMeiosis specific with OB-fold. (471 aa)
PcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
Rfc5AAA domain-containing protein. (340 aa)
ENSSTOP00000025372CBFD_NFYB_HMF domain-containing protein. (134 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (115 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
RPA3Replication protein A3. (121 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
ENSSTOP00000028717RING-type domain-containing protein. (95 aa)
ENSSTOP00000029771AAA domain-containing protein. (336 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
Server load: low (18%) [HD]