STRINGSTRING
PRKCG PRKCG PDE1C PDE1C PLCB2 PLCB2 PPP2R1B PPP2R1B GNB2 GNB2 GNG2 GNG2 GNAQ GNAQ I3MUP6_ICTTR I3MUP6_ICTTR Prkx Prkx PDE4D PDE4D GNG8 GNG8 I3N418_ICTTR I3N418_ICTTR PPP2R5D PPP2R5D GNA11 GNA11 GNAT3 GNAT3 GNA15 GNA15 GNG7 GNG7 SNX19 SNX19 Gng10 Gng10 CAMK2G CAMK2G PLCB4 PLCB4 DCLK1 DCLK1 PDE4B PDE4B PRKAR2A PRKAR2A PPP1CA PPP1CA PDE4A PDE4A PRKAR2B PRKAR2B CDK5 CDK5 CAMKK1 CAMKK1 PLA2G4A PLA2G4A Gng14 Gng14 PLCB3 PLCB3 ADCY8 ADCY8 THAP6 THAP6 CAMKK2 CAMKK2 PRKACB PRKACB ADCY7 ADCY7 PDE1B PDE1B PDYN PDYN ENSSTOP00000027631 ENSSTOP00000027631 Ppp2cb Ppp2cb ADCY5 ADCY5 Pde4c Pde4c OPRM1 OPRM1 PDE1A PDE1A PPP1R1B PPP1R1B GNG3 GNG3 PPP2R1A PPP2R1A PRKACA PRKACA ADCY4 ADCY4 PRKAR1B PRKAR1B ADCY6 ADCY6 GNG13 GNG13 GNG12 GNG12 CAMK4 CAMK4 PRKCD PRKCD ADCY2 ADCY2 ADCY9 ADCY9 GNB4 GNB4 PTRHD1 PTRHD1 ADCY3 ADCY3 POMC POMC GNGT2 GNGT2 GNG5 GNG5 GNA14 GNA14 GNAI3 GNAI3 ADCY1 ADCY1 LRBA LRBA GNGT1 GNGT1 GNG11 GNG11 GNB1 GNB1 PPP2CA PPP2CA GNAL GNAL NBEA NBEA GNAI1 GNAI1 PRKAR1A PRKAR1A GNB5 GNB5 I3MMQ2_ICTTR I3MMQ2_ICTTR CNBD2 CNBD2 GNB3 GNB3 GRK2 GRK2 GNG4 GNG4 PLCB1 PLCB1 GNAI2 GNAI2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PDE1CPhosphodiesterase. (769 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (658 aa)
GNB2G protein subunit beta 2. (371 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
GNAQG protein subunit alpha q. (313 aa)
I3MUP6_ICTTRGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PrkxUncharacterized protein. (330 aa)
PDE4DPhosphodiesterase 4D; Belongs to the cyclic nucleotide phosphodiesterase family. (808 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
I3N418_ICTTRGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (603 aa)
GNA11G protein subunit alpha 11. (359 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
GNA15G protein subunit alpha 15. (325 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
SNX19Sorting nexin 19. (997 aa)
Gng10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (512 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
DCLK1Doublecortin like kinase 1. (761 aa)
PDE4BPhosphodiesterase. (737 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (399 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
PDE4APhosphodiesterase. (776 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (417 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
CAMKK1Calcium/calmodulin dependent protein kinase kinase 1. (505 aa)
PLA2G4APhospholipase A2. (750 aa)
Gng14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1255 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
THAP6THAP domain containing 6. (217 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (587 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
PDE1BPhosphodiesterase. (535 aa)
PDYNProdynorphin. (245 aa)
ENSSTOP00000027631SER_THR_PHOSPHATASE domain-containing protein. (235 aa)
Ppp2cbSerine/threonine-protein phosphatase. (274 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
Pde4cPhosphodiesterase. (563 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (326 aa)
PDE1APhosphodiesterase. (544 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (203 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (334 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
GNG13G protein subunit gamma 13. (67 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (955 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
GNB4G protein subunit beta 4. (340 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
POMCProopiomelanocortin. (212 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNA14G protein subunit alpha 14. (355 aa)
GNAI3G protein subunit alpha i3. (354 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
LRBALPS responsive beige-like anchor protein. (2859 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNB1G protein subunit beta 1. (340 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
GNALG protein subunit alpha L. (378 aa)
NBEANeurobeachin. (2929 aa)
GNAI1G protein subunit alpha i1. (354 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
GNB5G protein subunit beta 5. (386 aa)
I3MMQ2_ICTTRUncharacterized protein. (384 aa)
CNBD2Cyclic nucleotide binding domain containing 2. (560 aa)
GNB3G protein subunit beta 3. (340 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (690 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (77 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
GNAI2G protein subunit alpha i2. (355 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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