STRINGSTRING
NEDD4 NEDD4 PIK3R1 PIK3R1 PSENEN PSENEN LOC101975023 LOC101975023 LOC101964641 LOC101964641 HRAS HRAS ENSSTOP00000028703 ENSSTOP00000028703 SOS1 SOS1 ENSSTOP00000030902 ENSSTOP00000030902 Csde1 Csde1 ENSSTOP00000031366 ENSSTOP00000031366 NRG1 NRG1 WWOX WWOX LOC101976832 LOC101976832 APH1A APH1A WWP1 WWP1 UBA52 UBA52 EREG EREG ERBB4 ERBB4 EGFR EGFR SHC1 SHC1 NRAS NRAS APH1B APH1B FNDC3B FNDC3B ITCH ITCH BTC BTC PIK3CA PIK3CA GRB2 GRB2 FNDC3A FNDC3A Rps27a Rps27a KRAS KRAS NCSTN NCSTN ESR1 ESR1 MXD4 MXD4 NRG2 NRG2 LOC101966763 LOC101966763 ADAP1 ADAP1 ERAS ERAS Stmn1 Stmn1 ADAP2 ADAP2 GFAP GFAP ERBB3 ERBB3 HBEGF HBEGF PSEN2 PSEN2 NRG4 NRG4 PSEN1 PSEN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NEDD4E3 ubiquitin-protein ligase. (901 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
LOC101975023CSD_1 domain-containing protein. (729 aa)
LOC101964641Uncharacterized protein. (400 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1334 aa)
ENSSTOP00000030902Uncharacterized protein. (380 aa)
Csde1Uncharacterized protein. (555 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
NRG1Neuregulin 1. (700 aa)
WWOXWW domain containing oxidoreductase. (415 aa)
LOC101976832Uncharacterized protein. (1356 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
WWP1E3 ubiquitin-protein ligase. (923 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
EREGEpiregulin. (163 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
EGFRReceptor protein-tyrosine kinase. (1192 aa)
SHC1SHC adaptor protein 1. (583 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (290 aa)
FNDC3BFibronectin type III domain containing 3B. (1208 aa)
ITCHE3 ubiquitin-protein ligase. (855 aa)
BTCBetacellulin. (143 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
NCSTNNicastrin. (709 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (593 aa)
MXD4MAX dimerization protein 4. (186 aa)
NRG2Neuregulin 2. (767 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
ADAP1ArfGAP with dual PH domains 1. (303 aa)
ERASES cell expressed Ras. (227 aa)
Stmn1Stathmin; Belongs to the stathmin family. (149 aa)
ADAP2ArfGAP with dual PH domains 2. (272 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (430 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1248 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
NRG4Neuregulin 4. (123 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.