70 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	NOTCH2	Notch receptor 2. (2364 aa)
	POGLUT1	Protein O-glucosyltransferase 1. (392 aa)
	IKZF3	IKAROS family zinc finger 3. (509 aa)
	IKZF1	IKAROS family zinc finger 1. (539 aa)
	NOTCH3	Notch receptor 3. (2277 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
	YBX1	Y-box binding protein 1. (290 aa)
	CNTN1	Contactin 1. (627 aa)
	APH1B	Aph-1 homolog B, gamma-secretase subunit. (290 aa)
	Mamld1	Uncharacterized protein. (780 aa)
	ELF3	E74 like ETS transcription factor 3. (372 aa)
	Notch4	Uncharacterized protein. (1955 aa)
	JAG2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1106 aa)
	HEY2	Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
	NEURL1	Neuralized E3 ubiquitin protein ligase 1. (574 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (715 aa)
	Ywhaz	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
	DTX4	Deltex E3 ubiquitin ligase 4. (617 aa)
	APH1A	Aph-1 homolog A, gamma-secretase subunit. (265 aa)
	EGFR	Receptor protein-tyrosine kinase. (1192 aa)
	MIB1	Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
	NCSTN	Nicastrin. (709 aa)
	CRB1	Crumbs cell polarity complex component 1. (1406 aa)
	Rps27a	Ubiquitin-like domain-containing protein. (156 aa)
	LRBA	LPS responsive beige-like anchor protein. (2859 aa)
	HEYL	Hes related family bHLH transcription factor with YRPW motif like. (321 aa)
	IKZF4	IKAROS family zinc finger 4. (585 aa)
	NBEA	Neurobeachin. (2929 aa)
	TACC3	Transforming acidic coiled-coil containing protein 3. (835 aa)
	DNER	Delta/notch like EGF repeat containing. (738 aa)
	LOC101966763	Ubiquitin-like domain-containing protein. (156 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (321 aa)
	DLK1	Delta like non-canonical Notch ligand 1. (383 aa)
	PBX4	PBX homeobox 4. (355 aa)
	HES5	Hes family bHLH transcription factor 5. (141 aa)
	DTX2	Deltex E3 ubiquitin ligase 2. (619 aa)
	EP300	E1A binding protein p300. (2423 aa)
	Rfng	Uncharacterized protein. (190 aa)
	NEURL1B	Neuralized E3 ubiquitin protein ligase 1B. (314 aa)
	HEY1	Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
	LFNG	Beta-1,3-N-acetylglucosaminyltransferase. (320 aa)
	LOC101965246	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
	PSEN2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
	Ehf	PNT domain-containing protein. (170 aa)
	IKZF2	IKAROS family zinc finger 2. (526 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
	ENSSTOP00000025854	CSD_1 domain-containing protein. (317 aa)
	PBX1	PBX homeobox 1. (430 aa)
	PSENEN	Presenilin enhancer, gamma-secretase subunit. (101 aa)
	ENSSTOP00000026289	Uncharacterized protein. (885 aa)
	PBX3	PBX homeobox 3. (418 aa)
	ENSSTOP00000028703	Ubiquitin-like domain-containing protein. (122 aa)
	LOC101959658	Uncharacterized protein. (415 aa)
	ENSSTOP00000031366	Ubiquitin-like domain-containing protein. (95 aa)
	ENSSTOP00000031663	Uncharacterized protein. (187 aa)
	FCER2	Fc fragment of IgE receptor II. (319 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	POFUT1	Protein O-fucosyltransferase 1. (391 aa)
	TMED2	Transmembrane p24 trafficking protein 2. (128 aa)
	WWP2	E3 ubiquitin-protein ligase. (820 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	MAML1	Mastermind like transcriptional coactivator 1. (1024 aa)
	PBX2	PBX homeobox 2. (430 aa)
	ITCH	E3 ubiquitin-protein ligase. (855 aa)
	Mov10	AAA_12 domain-containing protein. (1054 aa)
	ADAM10	ADAM metallopeptidase domain 10. (748 aa)
	KAT2B	Lysine acetyltransferase 2B. (731 aa)
	NOTCH1	Notch receptor 1. (2466 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	APH1A	ENSSTOP00000000507	ENSSTOP00000005403	ADAM metallopeptidase domain 10.	Aph-1 homolog A, gamma-secretase subunit.	0.519
ADAM10	CRB1	ENSSTOP00000000507	ENSSTOP00000008143	ADAM metallopeptidase domain 10.	Crumbs cell polarity complex component 1.	0.546
ADAM10	DLL1	ENSSTOP00000000507	ENSSTOP00000018225	ADAM metallopeptidase domain 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.754
ADAM10	DLL4	ENSSTOP00000000507	ENSSTOP00000002756	ADAM metallopeptidase domain 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.663
ADAM10	JAG1	ENSSTOP00000000507	ENSSTOP00000026569	ADAM metallopeptidase domain 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.631
ADAM10	JAG2	ENSSTOP00000000507	ENSSTOP00000017412	ADAM metallopeptidase domain 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.631
ADAM10	NCSTN	ENSSTOP00000000507	ENSSTOP00000007910	ADAM metallopeptidase domain 10.	Nicastrin.	0.673
ADAM10	NOTCH1	ENSSTOP00000000507	ENSSTOP00000005319	ADAM metallopeptidase domain 10.	Notch receptor 1.	0.768
ADAM10	NOTCH2	ENSSTOP00000000507	ENSSTOP00000004190	ADAM metallopeptidase domain 10.	Notch receptor 2.	0.739
ADAM10	NOTCH3	ENSSTOP00000000507	ENSSTOP00000003054	ADAM metallopeptidase domain 10.	Notch receptor 3.	0.640
ADAM10	PSEN1	ENSSTOP00000000507	ENSSTOP00000025290	ADAM metallopeptidase domain 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.577
ADAM10	PSEN2	ENSSTOP00000000507	ENSSTOP00000024249	ADAM metallopeptidase domain 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.542
ADAM10	PSENEN	ENSSTOP00000000507	ENSSTOP00000026270	ADAM metallopeptidase domain 10.	Presenilin enhancer, gamma-secretase subunit.	0.640
AKT1	CRB1	ENSSTOP00000028457	ENSSTOP00000008143	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Crumbs cell polarity complex component 1.	0.519
AKT1	DLL1	ENSSTOP00000028457	ENSSTOP00000018225	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.448
AKT1	DLL4	ENSSTOP00000028457	ENSSTOP00000002756	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.475
AKT1	DNER	ENSSTOP00000028457	ENSSTOP00000012024	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Delta/notch like EGF repeat containing.	0.514
AKT1	EGFR	ENSSTOP00000028457	ENSSTOP00000006038	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor protein-tyrosine kinase.	0.528
AKT1	ENSSTOP00000025854	ENSSTOP00000028457	ENSSTOP00000025854	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CSD_1 domain-containing protein.	0.454
AKT1	EP300	ENSSTOP00000028457	ENSSTOP00000000650	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	E1A binding protein p300.	0.850