STRINGSTRING
FGD3 FGD3 LOC101963830 LOC101963830 Rps27a Rps27a TGM6 TGM6 NCSTN NCSTN VAV3 VAV3 SQSTM1 SQSTM1 MCF2 MCF2 ENSSTOP00000031366 ENSSTOP00000031366 ENSSTOP00000031310 ENSSTOP00000031310 PLEKHG5 PLEKHG5 LOC101961455 LOC101961455 NGF NGF SOS1 SOS1 ARHGEF6 ARHGEF6 FGD4 FGD4 ARHGEF10L ARHGEF10L Akap13 Akap13 ENSSTOP00000028703 ENSSTOP00000028703 ARHGEF7 ARHGEF7 ABR ABR TRIO TRIO ITGB3BP ITGB3BP PSENEN PSENEN Bex3 Bex3 ARHGEF4 ARHGEF4 ARHGEF3 ARHGEF3 RTN4 RTN4 ARHGEF2 ARHGEF2 TIAM2 TIAM2 Arhgef25 Arhgef25 GNA13 GNA13 AATF AATF ARHGEF1 ARHGEF1 Casp3 Casp3 ADAM17 ADAM17 Rhoa Rhoa UBA52 UBA52 ARHGEF39 ARHGEF39 CASP2 CASP2 Ywhae Ywhae Tgm3 Tgm3 OMG OMG ARHGEF15 ARHGEF15 KALRN KALRN IKBKB IKBKB TIAM1 TIAM1 APH1A APH1A LOC101973389 LOC101973389 RAC1 RAC1 TRAF6 TRAF6 NET1 NET1 ENSSTOP00000025973 ENSSTOP00000025973 PSEN1 PSEN1 IRAK1 IRAK1 MCF2L MCF2L ARHGEF9 ARHGEF9 PSEN2 PSEN2 ARHGEF33 ARHGEF33 RTN4R RTN4R BCL2L11 BCL2L11 ARHGEF38 ARHGEF38 ARHGEF11 ARHGEF11 VAV2 VAV2 ITSN1 ITSN1 PLEKHG2 PLEKHG2 NGEF NGEF ARHGEF10 ARHGEF10 ARHGEF19 ARHGEF19 ARHGEF5 ARHGEF5 CCDC71L CCDC71L LOC101966763 LOC101966763 ECT2L ECT2L LINGO2 LINGO2 LINGO1 LINGO1 NFKBIA NFKBIA NGFR NGFR BAD BAD ARHGEF37 ARHGEF37 LOC101959358 LOC101959358 ARHGEF26 ARHGEF26 Ect2 Ect2 ARHGEF16 ARHGEF16 FGD1 FGD1 PRDM4 PRDM4 APH1B APH1B FGD2 FGD2 ARHGEF12 ARHGEF12 ARHGDIA ARHGDIA RIPK2 RIPK2 ARHGEF40 ARHGEF40 ARHGEF17 ARHGEF17 MYD88 MYD88 MAPK8 MAPK8 NFKB1 NFKB1 VAV1 VAV1 SESTD1 SESTD1 MCF2L2 MCF2L2 Mag Mag
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGD3FYVE, RhoGEF and PH domain containing 3. (725 aa)
LOC101963830Uncharacterized protein. (1013 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
TGM6Transglutaminase 6. (706 aa)
NCSTNNicastrin. (709 aa)
VAV3Vav guanine nucleotide exchange factor 3. (847 aa)
SQSTM1Sequestosome 1. (440 aa)
MCF2MCF.2 cell line derived transforming sequence. (1096 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
ENSSTOP00000031310Uncharacterized protein; Belongs to the peptidase C14A family. (233 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1053 aa)
LOC101961455Uncharacterized protein. (334 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (305 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1334 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (778 aa)
FGD4FYVE, RhoGEF and PH domain containing 4. (939 aa)
ARHGEF10LRho guanine nucleotide exchange factor 10 like. (1275 aa)
Akap13Uncharacterized protein. (1423 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (713 aa)
ABRABR activator of RhoGEF and GTPase. (871 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3069 aa)
ITGB3BPIntegrin subunit beta 3 binding protein. (180 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
Bex3Uncharacterized protein. (102 aa)
ARHGEF4Rho guanine nucleotide exchange factor 4. (630 aa)
ARHGEF3Rho guanine nucleotide exchange factor 3. (532 aa)
RTN4Reticulon. (1177 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (869 aa)
TIAM2T cell lymphoma invasion and metastasis 2. (1661 aa)
Arhgef25Uncharacterized protein. (619 aa)
GNA13G protein subunit alpha 13. (306 aa)
AATFApoptosis antagonizing transcription factor. (506 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (972 aa)
Casp3Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
ADAM17ADAM metallopeptidase domain 17. (811 aa)
RhoaRas homolog family member A. (193 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ARHGEF39Rho guanine nucleotide exchange factor 39. (335 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (448 aa)
Ywhae14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
Tgm3TGc domain-containing protein. (697 aa)
OMGOligodendrocyte myelin glycoprotein. (443 aa)
ARHGEF15Rho guanine nucleotide exchange factor 15. (849 aa)
KALRNKalirin RhoGEF kinase. (2951 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1567 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
LOC101973389Uncharacterized protein. (182 aa)
RAC1Rac family small GTPase 1. (211 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa)
NET1Neuroepithelial cell transforming 1. (595 aa)
ENSSTOP0000002597314_3_3 domain-containing protein. (119 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (715 aa)
MCF2LMCF.2 cell line derived transforming sequence like. (1127 aa)
ARHGEF9Cdc42 guanine nucleotide exchange factor 9. (523 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
ARHGEF33Rho guanine nucleotide exchange factor 33. (850 aa)
RTN4RReticulon 4 receptor. (473 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (195 aa)
ARHGEF38Rho guanine nucleotide exchange factor 38. (772 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1494 aa)
VAV2Vav guanine nucleotide exchange factor 2. (745 aa)
ITSN1Intersectin 1. (1655 aa)
PLEKHG2Pleckstrin homology and RhoGEF domain containing G2. (1390 aa)
NGEFNeuronal guanine nucleotide exchange factor. (707 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10. (933 aa)
ARHGEF19Rho guanine nucleotide exchange factor 19. (800 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1570 aa)
CCDC71LUncharacterized protein. (176 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
ECT2LEpithelial cell transforming 2 like. (853 aa)
LINGO2Leucine rich repeat and Ig domain containing 2. (606 aa)
LINGO1Leucine rich repeat and Ig domain containing 1. (620 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
NGFRNerve growth factor receptor. (428 aa)
BADBCL2 associated agonist of cell death. (208 aa)
ARHGEF37Rho guanine nucleotide exchange factor 37. (672 aa)
LOC101959358Uncharacterized protein. (193 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (851 aa)
Ect2Uncharacterized protein. (188 aa)
ARHGEF16Rho guanine nucleotide exchange factor 16. (704 aa)
FGD1FYVE, RhoGEF and PH domain containing 1. (937 aa)
PRDM4PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (801 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (290 aa)
FGD2FYVE, RhoGEF and PH domain containing 2. (643 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1518 aa)
ARHGDIARho GDP dissociation inhibitor alpha. (204 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
ARHGEF40Rho guanine nucleotide exchange factor 40. (1516 aa)
ARHGEF17Rho guanine nucleotide exchange factor 17. (2060 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
NFKB1Nuclear factor kappa B subunit 1. (985 aa)
VAV1Vav guanine nucleotide exchange factor 1. (822 aa)
SESTD1SEC14 and spectrin domain containing 1. (696 aa)
MCF2L2MCF.2 cell line derived transforming sequence-like 2. (1115 aa)
MagUncharacterized protein. (64 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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