STRINGSTRING
PIK3CB PIK3CB LOC101968188 LOC101968188 LOC101968486 LOC101968486 HLA-DQB1 HLA-DQB1 Rps27a Rps27a ITK ITK Map3k20 Map3k20 PAK2 PAK2 Card11 Card11 TRAF6 TRAF6 UBE2D1 UBE2D1 IKBKB IKBKB PLCG2 PLCG2 UBA52 UBA52 HLA-DPB1 HLA-DPB1 HLA-DPA1 HLA-DPA1 GRAP2 GRAP2 I3LZW4_ICTTR I3LZW4_ICTTR Pik3r2 Pik3r2 NCK1 NCK1 LOC101954381 LOC101954381 MAP3K7 MAP3K7 ENSSTOP00000031366 ENSSTOP00000031366 LOC101970873 LOC101970873 SPNS1 SPNS1 ENSSTOP00000029566 ENSSTOP00000029566 ENSSTOP00000028911 ENSSTOP00000028911 ENSSTOP00000028703 ENSSTOP00000028703 UBE2D2 UBE2D2 PTPRJ PTPRJ ENSSTOP00000027615 ENSSTOP00000027615 IKBKG IKBKG PAK3 PAK3 PTPRC PTPRC PIK3R1 PIK3R1 LAT LAT CD101 CD101 TRAT1 TRAT1 CD4 CD4 WAS WAS BCL10 BCL10 TRAV29DV5 TRAV29DV5 LOC101957991 LOC101957991 CSK CSK CD247 CD247 CCDC71L CCDC71L LOC101966763 LOC101966763 PRKCQ PRKCQ MALT1 MALT1 CD3D CD3D PTEN PTEN TAB2 TAB2 LCP2 LCP2 CHUK CHUK LOC101970595 LOC101970595 PAG1 PAG1 UBE2V1 UBE2V1 PDPK1 PDPK1 PIK3CA PIK3CA PAK1 PAK1 PLCG1 PLCG1 NFKB1 NFKB1 INPP5D INPP5D ZAP70 ZAP70 SPNS3 SPNS3 HLA-DRA HLA-DRA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC101968188Ig-like domain-containing protein. (266 aa)
LOC101968486Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (269 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
ITKTyrosine-protein kinase. (620 aa)
Map3k20Uncharacterized protein. (800 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
Card11Uncharacterized protein. (1152 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (288 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (254 aa)
GRAP2GRB2 related adaptor protein 2. (324 aa)
I3LZW4_ICTTRUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (129 aa)
Pik3r2Uncharacterized protein. (724 aa)
NCK1Cytoplasmic protein. (377 aa)
LOC101954381UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (176 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
LOC101970873Ig-like domain-containing protein. (251 aa)
SPNS1Sphingolipid transporter 1 (putative). (528 aa)
ENSSTOP00000029566UBIQUITIN_CONJUGAT_2 domain-containing protein. (122 aa)
ENSSTOP00000028911UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (203 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (143 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1197 aa)
ENSSTOP00000027615Uncharacterized protein. (247 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (492 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1180 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
LATLinker for activation of T cells. (234 aa)
CD101CD101 molecule. (938 aa)
TRAT1T cell receptor associated transmembrane adaptor 1. (186 aa)
CD4CD4 molecule. (451 aa)
WASWASP actin nucleation promoting factor. (503 aa)
BCL10BCL10 immune signaling adaptor. (153 aa)
TRAV29DV5T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene). (133 aa)
LOC101957991Ig-like domain-containing protein. (249 aa)
CSKTyrosine-protein kinase. (450 aa)
CD247CD247 molecule. (144 aa)
CCDC71LUncharacterized protein. (176 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
MALT1MALT1 paracaspase. (747 aa)
CD3DCD3d molecule. (170 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (692 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (769 aa)
LOC101970595Ig-like domain-containing protein. (264 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (430 aa)
UBE2V1Ubiquitin conjugating enzyme E2 V1. (139 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (556 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
NFKB1Nuclear factor kappa B subunit 1. (985 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1213 aa)
ZAP70Tyrosine-protein kinase. (608 aa)
SPNS3Sphingolipid transporter 3 (putative). (515 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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