27 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NCOR2	Nuclear receptor corepressor 2. (2447 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	UBE2D1	Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	SKIL	SKI like proto-oncogene. (677 aa)
	Rps27a	Ubiquitin-like domain-containing protein. (156 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	Hdac1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (399 aa)
	NEDD4L	NEDD4 like E3 ubiquitin protein ligase. (962 aa)
	PPM1A	Protein phosphatase, Mg2+/Mn2+ dependent 1A. (382 aa)
	MAPK1	Mitogen-activated protein kinase. (331 aa)
	TGIF1	TGFB induced factor homeobox 1. (272 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
	SNW1	SNW domain containing 1. (554 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	ENSSTOP00000031366	Ubiquitin-like domain-containing protein. (95 aa)
	SKI	SKI proto-oncogene. (730 aa)
	ENSSTOP00000028703	Ubiquitin-like domain-containing protein. (122 aa)
	NCOR1	Nuclear receptor corepressor 1. (2529 aa)
	ENSSTOP00000026639	Hist_deacetyl domain-containing protein. (323 aa)
	TRIM33	Tripartite motif containing 33. (1028 aa)
	LOC101966763	Ubiquitin-like domain-containing protein. (156 aa)
	USP9X	Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2554 aa)
	MAPK3	Mitogen-activated protein kinase. (361 aa)
	TGIF2	TGFB induced factor homeobox 2. (237 aa)
	SMURF2	E3 ubiquitin-protein ligase. (740 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1B4	SNW1	ENSSTOP00000002067	ENSSTOP00000002944	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	SNW domain containing 1.	0.933
ENSSTOP00000026639	ENSSTOP00000028703	ENSSTOP00000026639	ENSSTOP00000028703	Hist_deacetyl domain-containing protein.	Ubiquitin-like domain-containing protein.	0.572
ENSSTOP00000026639	NCOR1	ENSSTOP00000026639	ENSSTOP00000028352	Hist_deacetyl domain-containing protein.	Nuclear receptor corepressor 1.	0.946
ENSSTOP00000026639	NCOR2	ENSSTOP00000026639	ENSSTOP00000024745	Hist_deacetyl domain-containing protein.	Nuclear receptor corepressor 2.	0.946
ENSSTOP00000026639	PARP1	ENSSTOP00000026639	ENSSTOP00000014322	Hist_deacetyl domain-containing protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.497
ENSSTOP00000026639	SMAD2	ENSSTOP00000026639	ENSSTOP00000003397	Hist_deacetyl domain-containing protein.	Mothers against decapentaplegic homolog.	0.822
ENSSTOP00000026639	SMAD3	ENSSTOP00000026639	ENSSTOP00000009229	Hist_deacetyl domain-containing protein.	Mothers against decapentaplegic homolog.	0.762
ENSSTOP00000026639	SMAD4	ENSSTOP00000026639	ENSSTOP00000016654	Hist_deacetyl domain-containing protein.	Mothers against decapentaplegic homolog.	0.803
ENSSTOP00000026639	SNW1	ENSSTOP00000026639	ENSSTOP00000002944	Hist_deacetyl domain-containing protein.	SNW domain containing 1.	0.674
ENSSTOP00000026639	TGIF1	ENSSTOP00000026639	ENSSTOP00000014856	Hist_deacetyl domain-containing protein.	TGFB induced factor homeobox 1.	0.654
ENSSTOP00000026639	TGIF2	ENSSTOP00000026639	ENSSTOP00000001539	Hist_deacetyl domain-containing protein.	TGFB induced factor homeobox 2.	0.599
ENSSTOP00000026639	TRIM33	ENSSTOP00000026639	ENSSTOP00000025975	Hist_deacetyl domain-containing protein.	Tripartite motif containing 33.	0.416
ENSSTOP00000026639	UBA52	ENSSTOP00000026639	ENSSTOP00000004191	Hist_deacetyl domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.572
ENSSTOP00000028703	ENSSTOP00000026639	ENSSTOP00000028703	ENSSTOP00000026639	Ubiquitin-like domain-containing protein.	Hist_deacetyl domain-containing protein.	0.572
ENSSTOP00000028703	ENSSTOP00000031366	ENSSTOP00000028703	ENSSTOP00000031366	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.985
ENSSTOP00000028703	Hdac1	ENSSTOP00000028703	ENSSTOP00000010833	Ubiquitin-like domain-containing protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.572
ENSSTOP00000028703	LOC101966763	ENSSTOP00000028703	ENSSTOP00000019666	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.985
ENSSTOP00000028703	MAPK1	ENSSTOP00000028703	ENSSTOP00000013254	Ubiquitin-like domain-containing protein.	Mitogen-activated protein kinase.	0.500
ENSSTOP00000028703	MAPK3	ENSSTOP00000028703	ENSSTOP00000000787	Ubiquitin-like domain-containing protein.	Mitogen-activated protein kinase.	0.500
ENSSTOP00000028703	NCOR1	ENSSTOP00000028703	ENSSTOP00000028352	Ubiquitin-like domain-containing protein.	Nuclear receptor corepressor 1.	0.560