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METAP2 METAP2 GUCA1C GUCA1C RCVRN RCVRN GNB1 GNB1 GRK4 GRK4 PPEF2 PPEF2 GNGT1 GNGT1 NMT1 NMT1 PDE6H PDE6H PDE6A PDE6A CAMKMT CAMKMT I3M9X0_ICTTR I3M9X0_ICTTR METAP1 METAP1 PDE6G PDE6G GUCY2D GUCY2D CNGA1 CNGA1 CNGB3 CNGB3 RGS9 RGS9 LOC101969867 LOC101969867 GUCA1B GUCA1B RGS9BP RGS9BP PDE6C PDE6C RHO RHO GRK1 GRK1 VEZT VEZT GNAT1 GNAT1 GNB5 GNB5 Fnta Fnta NMT2 NMT2 SAG SAG Guca1a Guca1a PPEF1 PPEF1 Grk7 Grk7 Fntb Fntb PDE6B PDE6B ENSSTOP00000024359 ENSSTOP00000024359
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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METAP2Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (478 aa)
GUCA1CGuanylate cyclase activator 1C. (231 aa)
RCVRNRecoverin. (202 aa)
GNB1G protein subunit beta 1. (340 aa)
GRK4G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (574 aa)
PPEF2Serine/threonine-protein phosphatase. (763 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
NMT1Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (496 aa)
PDE6HRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G- protein-mediated phototransduction in vertebrate rods and cones; Belongs to the rod/cone cGMP-PDE gamma subunit family. (83 aa)
PDE6APhosphodiesterase. (860 aa)
CAMKMTCalmodulin-lysine N-methyltransferase. (323 aa)
I3M9X0_ICTTRCyclic nucleotide-binding domain-containing protein. (870 aa)
METAP1Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). (386 aa)
PDE6GPhosphodiesterase 6G. (87 aa)
GUCY2DGuanylate cyclase. (1108 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (683 aa)
CNGB3Cyclic nucleotide gated channel subunit beta 3. (786 aa)
RGS9Regulator of G protein signaling 9. (675 aa)
LOC101969867Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (209 aa)
GUCA1BGuanylate cyclase activator 1B. (201 aa)
RGS9BPRegulator of G protein signaling 9 binding protein. (236 aa)
PDE6CPhosphodiesterase. (862 aa)
RHORhodopsin. (348 aa)
GRK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (564 aa)
VEZTVezatin, adherens junctions transmembrane protein. (783 aa)
GNAT1G protein subunit alpha transducin 1. (350 aa)
GNB5G protein subunit beta 5. (386 aa)
FntaUncharacterized protein. (379 aa)
NMT2Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (498 aa)
SAGS-antigen visual arrestin. (401 aa)
Guca1aUncharacterized protein. (202 aa)
PPEF1Serine/threonine-protein phosphatase with EF-hands. (656 aa)
Grk7Rhodopsin kinase GRK7; Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO). (548 aa)
FntbProtein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. (471 aa)
PDE6BPhosphodiesterase. (855 aa)
ENSSTOP00000024359Uncharacterized protein. (354 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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