STRINGSTRING
MAPK10 MAPK10 MAPK3 MAPK3 MAP3K6 MAP3K6 CDK6 CDK6 CDKN2C CDKN2C MAPK8 MAPK8 RBBP4 RBBP4 MAP2K3 MAP2K3 Rps27a Rps27a MAP3K5 MAP3K5 MAPKAPK2 MAPKAPK2 PHC2 PHC2 EED EED UBA52 UBA52 Mdm4 Mdm4 EZH1 EZH1 FOS FOS RBBP7 RBBP7 TNIK TNIK Cdk4 Cdk4 MAPK1 MAPK1 ENSSTOP00000031366 ENSSTOP00000031366 MINK1 MINK1 MAPK11 MAPK11 Mov10 Mov10 CBX2 CBX2 MAP4K4 MAP4K4 LOC101957760 LOC101957760 LOC101957469 LOC101957469 Cdkn2d Cdkn2d MAP2K4 MAP2K4 NPTX1 NPTX1 TXN TXN LOC101966763 LOC101966763 TP53 TP53 CDKN2B CDKN2B FOSL2 FOSL2 I3NAC7_ICTTR I3NAC7_ICTTR JUN JUN KDM6B KDM6B I3NE23_ICTTR I3NE23_ICTTR MAPK14 MAPK14 NME8 NME8 LOC101972712 LOC101972712 ENSSTOP00000024190 ENSSTOP00000024190 MAPKAPK5 MAPKAPK5 ENSSTOP00000025853 ENSSTOP00000025853 ENSSTOP00000026289 ENSSTOP00000026289 PHC1 PHC1 SUZ12 SUZ12 NPTXR NPTXR ENSSTOP00000028703 ENSSTOP00000028703 NPTX2 NPTX2 CBX7 CBX7 EZH2 EZH2 MAPKAPK3 MAPKAPK3 NME9 NME9 MAP2K7 MAP2K7 MAPK9 MAPK9 Mdm2 Mdm2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK10Mitogen-activated protein kinase. (492 aa)
MAPK3Mitogen-activated protein kinase. (361 aa)
MAP3K6Mitogen-activated protein kinase kinase kinase 6. (1293 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (170 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
RBBP4RB binding protein 4, chromatin remodeling factor. (425 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1307 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (358 aa)
PHC2Polyhomeotic homolog 2. (855 aa)
EEDEmbryonic ectoderm development. (441 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
Mdm4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (747 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (425 aa)
TNIKTRAF2 and NCK interacting kinase. (1360 aa)
Cdk4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
MAPK1Mitogen-activated protein kinase. (331 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
MINK1Misshapen like kinase 1. (1342 aa)
MAPK11Mitogen-activated protein kinase. (325 aa)
Mov10AAA_12 domain-containing protein. (1054 aa)
CBX2Chromobox 2. (491 aa)
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4. (1244 aa)
LOC101957760Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC101957469Histone H2B type 1-K. (126 aa)
Cdkn2dANK_REP_REGION domain-containing protein. (166 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (360 aa)
NPTX1Neuronal pentraxin 1. (432 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (162 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (326 aa)
I3NAC7_ICTTRProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (349 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
KDM6BLysine demethylase 6B. (1651 aa)
I3NE23_ICTTRANK_REP_REGION domain-containing protein. (150 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
NME8NME/NM23 family member 8. (518 aa)
LOC101972712Histone H2B type 1. (126 aa)
ENSSTOP00000024190Protein kinase domain-containing protein. (266 aa)
MAPKAPK5MAPK activated protein kinase 5. (472 aa)
ENSSTOP00000025853Uncharacterized protein. (42 aa)
ENSSTOP00000026289Uncharacterized protein. (885 aa)
PHC1Polyhomeotic homolog 1. (1013 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (739 aa)
NPTXRNeuronal pentraxin receptor. (471 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
NPTX2Neuronal pentraxin 2. (423 aa)
CBX7Chromobox 7. (250 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (757 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
NME9NME/NM23 family member 9; Belongs to the NDK family. (365 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (469 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
Mdm2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (489 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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