STRINGSTRING
ETV3 ETV3 Mov10 Mov10 MAPK1 MAPK1 Mdm2 Mdm2 CDK6 CDK6 MAPK3 MAPK3 I3MEF2_ICTTR I3MEF2_ICTTR Rps27a Rps27a ID1 ID1 Mdm4 Mdm4 UBA52 UBA52 ENSSTOP00000031366 ENSSTOP00000031366 ENSSTOP00000030720 ENSSTOP00000030720 ETS1 ETS1 ENSSTOP00000028703 ENSSTOP00000028703 ENSSTOP00000026289 ENSSTOP00000026289 CDKN2C CDKN2C Cdk4 Cdk4 ENSSTOP00000024190 ENSSTOP00000024190 I3NE23_ICTTR I3NE23_ICTTR CDKN2B CDKN2B TP53 TP53 LOC101966763 LOC101966763 ETS2 ETS2 Cdkn2d Cdkn2d ERF ERF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ETV3ETS variant 3. (510 aa)
Mov10AAA_12 domain-containing protein. (1054 aa)
MAPK1Mitogen-activated protein kinase. (331 aa)
Mdm2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (489 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
MAPK3Mitogen-activated protein kinase. (361 aa)
I3MEF2_ICTTRETS domain-containing protein. (135 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (151 aa)
Mdm4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
ENSSTOP00000030720ETS domain-containing protein. (133 aa)
ETS1ETS proto-oncogene 1, transcription factor. (441 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
ENSSTOP00000026289Uncharacterized protein. (885 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (170 aa)
Cdk4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
ENSSTOP00000024190Protein kinase domain-containing protein. (266 aa)
I3NE23_ICTTRANK_REP_REGION domain-containing protein. (150 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (162 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (471 aa)
Cdkn2dANK_REP_REGION domain-containing protein. (166 aa)
ERFETS2 repressor factor. (552 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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