34 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FNDC3A	Fibronectin type III domain containing 3A. (1198 aa)
	Cdc42	Uncharacterized protein. (191 aa)
	Pik3r2	Uncharacterized protein. (724 aa)
	GRAP2	GRB2 related adaptor protein 2. (324 aa)
	Cd86	Ig-like domain-containing protein. (289 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
	RICTOR	RPTOR independent companion of MTOR complex 2. (1660 aa)
	MAP3K8	Mitogen-activated protein kinase kinase kinase 8. (467 aa)
	RAC1	Rac family small GTPase 1. (211 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	PAK2	Non-specific serine/threonine protein kinase. (524 aa)
	TRIB3	Tribbles pseudokinase 3. (363 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (822 aa)
	MAPKAP1	MAPK associated protein 1. (522 aa)
	FNDC3B	Fibronectin type III domain containing 3B. (1208 aa)
	SRC	Tyrosine-protein kinase. (541 aa)
	LOC101976832	Uncharacterized protein. (1356 aa)
	CD28	CD28 molecule. (221 aa)
	CD276	CD276 molecule. (316 aa)
	I3N4S4_ICTTR	Uncharacterized protein. (162 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	PAK3	Non-specific serine/threonine protein kinase. (559 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	Pik3r3	Uncharacterized protein. (461 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	MLST8	MTOR associated protein, LST8 homolog. (326 aa)
	MAP3K14	Mitogen-activated protein kinase kinase kinase 14. (934 aa)
	LOC101966144	Uncharacterized protein. (147 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2577 aa)
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	PAK1	Non-specific serine/threonine protein kinase. (544 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (556 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSSTOP00000028457	ENSSTOP00000002612	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.968
AKT1	AKT3	ENSSTOP00000028457	ENSSTOP00000009513	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.896
AKT1	CD28	ENSSTOP00000028457	ENSSTOP00000018481	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CD28 molecule.	0.551
AKT1	Cd86	ENSSTOP00000028457	ENSSTOP00000002363	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ig-like domain-containing protein.	0.570
AKT1	Cdc42	ENSSTOP00000028457	ENSSTOP00000000717	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.698
AKT1	FYN	ENSSTOP00000028457	ENSSTOP00000006598	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.704
AKT1	GRB2	ENSSTOP00000028457	ENSSTOP00000011345	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Growth factor receptor bound protein 2.	0.697
AKT1	I3N4S4_ICTTR	ENSSTOP00000028457	ENSSTOP00000019370	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.698
AKT1	LOC101966144	ENSSTOP00000028457	ENSSTOP00000031379	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.698
AKT1	LYN	ENSSTOP00000028457	ENSSTOP00000029495	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.672
AKT1	MAP3K8	ENSSTOP00000028457	ENSSTOP00000006049	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 8.	0.872
AKT1	MAPKAP1	ENSSTOP00000028457	ENSSTOP00000010116	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MAPK associated protein 1.	0.934
AKT1	MLST8	ENSSTOP00000028457	ENSSTOP00000029682	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MTOR associated protein, LST8 homolog.	0.809
AKT1	MTOR	ENSSTOP00000028457	ENSSTOP00000032212	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.994
AKT1	PAK1	ENSSTOP00000028457	ENSSTOP00000011468	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.847
AKT1	PAK2	ENSSTOP00000028457	ENSSTOP00000007400	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.480
AKT1	PAK3	ENSSTOP00000028457	ENSSTOP00000026466	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.572
AKT1	PDPK1	ENSSTOP00000028457	ENSSTOP00000011658	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	3-phosphoinositide dependent protein kinase 1.	0.993
AKT1	PIK3CA	ENSSTOP00000028457	ENSSTOP00000011575	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.969
AKT1	PIK3R1	ENSSTOP00000028457	ENSSTOP00000026032	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphoinositide-3-kinase regulatory subunit 1.	0.950