STRINGSTRING
PSMD7 PSMD7 PSMA2 PSMA2 FZD1 FZD1 PSMA3 PSMA3 PSMB7 PSMB7 RAC3 RAC3 PSMD8 PSMD8 Psmc6 Psmc6 PRICKLE3 PRICKLE3 Psmb6 Psmb6 PSMD14 PSMD14 SMURF1 SMURF1 PSMA8 PSMA8 PRICKLE2 PRICKLE2 FZD4 FZD4 PSMB11 PSMB11 RAC2 RAC2 FZD5 FZD5 I3N1R8_ICTTR I3N1R8_ICTTR PARD6A PARD6A LOC101959358 LOC101959358 CLTB CLTB LOC101966763 LOC101966763 PSMB8 PSMB8 PFN1 PFN1 WNT5A WNT5A WNT11 WNT11 FZD8 FZD8 FHDC1 FHDC1 FZD2 FZD2 PSMD3 PSMD3 PSMF1 PSMF1 AP2A1 AP2A1 ARRB2 ARRB2 PSMB3 PSMB3 ENSSTOP00000024305 ENSSTOP00000024305 PSMD13 PSMD13 LOC101972090 LOC101972090 PSMD2 PSMD2 ENSSTOP00000025153 ENSSTOP00000025153 SMURF2 SMURF2 CLTC CLTC DVL3 DVL3 PSME1 PSME1 PRKCG PRKCG PSME3 PSME3 ROR1 ROR1 PSMA5 PSMA5 PSMD11 PSMD11 PRICKLE1 PRICKLE1 PSME2 PSME2 CLTA CLTA ENSSTOP00000028703 ENSSTOP00000028703 PSMA4 PSMA4 Prickle4 Prickle4 FZD7 FZD7 ENSSTOP00000029537 ENSSTOP00000029537 ENSSTOP00000030001 ENSSTOP00000030001 ENSSTOP00000031366 ENSSTOP00000031366 PSMD12 PSMD12 Psmc1 Psmc1 ENSSTOP00000031690 ENSSTOP00000031690 PSMD4 PSMD4 WNT4 WNT4 ROR2 ROR2 PSMB2 PSMB2 DAAM2 DAAM2 PSMB10 PSMB10 AP2B1 AP2B1 CLTCL1 CLTCL1 PRKCA PRKCA DAAM1 DAAM1 PSMB9 PSMB9 PSMD10 PSMD10 WNT1 WNT1 Rhoa Rhoa UBA52 UBA52 PSMC2 PSMC2 PSMA1 PSMA1 RAC1 RAC1 PSMB5 PSMB5 FZD6 FZD6 AP2M1 AP2M1 PSME4 PSME4 DVL2 DVL2 Psmc5 Psmc5 PSMD1 PSMD1 Rps27a Rps27a PSMB1 PSMB1 PSMC3 PSMC3 FZD3 FZD3 AP2A2 AP2A2 Psmd9 Psmd9 Psma6 Psma6 PSMB4 PSMB4 WNT5B WNT5B PRKCB PRKCB PSMA7 PSMA7 PSMC4 PSMC4 PSMD6 PSMD6 DVL1 DVL1 PSMD5 PSMD5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (643 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMB7Proteasome subunit beta. (277 aa)
RAC3Rac family small GTPase 3. (185 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
Psmc626S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (389 aa)
PRICKLE3Prickle planar cell polarity protein 3. (613 aa)
Psmb6Proteasome subunit beta. (239 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
SMURF1E3 ubiquitin-protein ligase. (753 aa)
PSMA8Proteasome subunit alpha type. (257 aa)
PRICKLE2Prickle planar cell polarity protein 2. (767 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
PSMB11Proteasome subunit beta. (293 aa)
RAC2Rac family small GTPase 2. (192 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
I3N1R8_ICTTRUncharacterized protein. (199 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
LOC101959358Uncharacterized protein. (193 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
LOC101966763Ubiquitin-like domain-containing protein. (156 aa)
PSMB8Proteasome subunit beta. (276 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (470 aa)
FHDC1FH2 domain containing 1. (1123 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (556 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (978 aa)
ARRB2Arrestin beta 2. (409 aa)
PSMB3Proteasome subunit beta. (205 aa)
ENSSTOP00000024305Uncharacterized protein. (210 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
LOC101972090AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
ENSSTOP00000025153PROTEASOME_ALPHA_1 domain-containing protein. (87 aa)
SMURF2E3 ubiquitin-protein ligase. (740 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1687 aa)
DVL3Dishevelled segment polarity protein 3. (717 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PSME3Proteasome activator subunit 3. (254 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (956 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PRICKLE1Prickle planar cell polarity protein 1. (833 aa)
PSME2Proteasome activator subunit 2. (239 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
ENSSTOP00000028703Ubiquitin-like domain-containing protein. (122 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
Prickle4Uncharacterized protein. (362 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (598 aa)
ENSSTOP00000029537Proteasome subunit beta. (200 aa)
ENSSTOP00000030001AAA domain-containing protein. (334 aa)
ENSSTOP00000031366Ubiquitin-like domain-containing protein. (95 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
Psmc1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
ENSSTOP00000031690ANK_REP_REGION domain-containing protein. (189 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (910 aa)
PSMB2Proteasome subunit beta. (201 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1067 aa)
PSMB10Proteasome subunit beta. (273 aa)
AP2B1AP complex subunit beta. (951 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1667 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (603 aa)
DAAM1Dishevelled associated activator of morphogenesis 1. (1077 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMD10ANK_REP_REGION domain-containing protein. (226 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
RhoaRas homolog family member A. (193 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
PSMA1Proteasome subunit alpha type. (266 aa)
RAC1Rac family small GTPase 1. (211 aa)
PSMB5Proteasome subunit beta. (220 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (711 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (435 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
Psmc5AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
Rps27aUbiquitin-like domain-containing protein. (156 aa)
PSMB1Proteasome subunit beta. (240 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (914 aa)
Psmd9PDZ domain-containing protein. (223 aa)
Psma6Proteasome subunit alpha type. (148 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (400 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa)
PSMA7Proteasome endopeptidase complex. (216 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
DVL1Dishevelled segment polarity protein 1. (696 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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