STRINGSTRING
RAP1A RAP1A SYT5 SYT5 GNB2 GNB2 GNG2 GNG2 CACNA2D1 CACNA2D1 GNAQ GNAQ I3MUP6_ICTTR I3MUP6_ICTTR CACNA1F CACNA1F GNG8 GNG8 KCNJ11 KCNJ11 I3N418_ICTTR I3N418_ICTTR GNA11 GNA11 GNA15 GNA15 GNG7 GNG7 ACSL3 ACSL3 SNX19 SNX19 Gng10 Gng10 KCNG2 KCNG2 CACNB2 CACNB2 ITPR2 ITPR2 RAPGEFL1 RAPGEFL1 ADRA2A ADRA2A ITPR3 ITPR3 CD36 CD36 ITPR1 ITPR1 PLCB2 PLCB2 SLC2A1 SLC2A1 LOC101967288 LOC101967288 KCNB1 KCNB1 CACNA1A CACNA1A PRKACB PRKACB CACNA1D CACNA1D THAP6 THAP6 PLCB3 PLCB3 Gng14 Gng14 ABCC8 ABCC8 ADCY5 ADCY5 RAPGEF3 RAPGEF3 GNG3 GNG3 RAPGEF4 RAPGEF4 PRKACA PRKACA ADCY6 ADCY6 CACNB3 CACNB3 GNG13 GNG13 GNG12 GNG12 KCNC2 KCNC2 GCG GCG FAP FAP GNB4 GNB4 ACSL4 ACSL4 GLP1R GLP1R GNGT2 GNGT2 GNG5 GNG5 GNA14 GNA14 CACNA1E CACNA1E GNGT1 GNGT1 GNG11 GNG11 SLC2A2 SLC2A2 RAPGEF5 RAPGEF5 GNB1 GNB1 CACNA2D2 CACNA2D2 GNAI1 GNAI1 KCNS3 KCNS3 GNB5 GNB5 CACNA1C CACNA1C GNB3 GNB3 GNG4 GNG4 PLCB1 PLCB1 GNAI2 GNAI2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
SYT5Synaptotagmin 5. (386 aa)
GNB2G protein subunit beta 2. (371 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1068 aa)
GNAQG protein subunit alpha q. (313 aa)
I3MUP6_ICTTRGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1981 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
I3N418_ICTTRGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)
GNA11G protein subunit alpha 11. (359 aa)
GNA15G protein subunit alpha 15. (325 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
SNX19Sorting nexin 19. (997 aa)
Gng10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
KCNG2Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family. (465 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (657 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
RAPGEFL1Rap guanine nucleotide exchange factor like 1. (696 aa)
ADRA2AAdrenoceptor alpha 2A; Belongs to the G-protein coupled receptor 1 family. (324 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
CD36CD36 molecule; Belongs to the CD36 family. (473 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2748 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
LOC101967288Uncharacterized protein. (848 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (859 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2092 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2179 aa)
THAP6THAP domain containing 6. (217 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1255 aa)
Gng14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ABCC8ATP binding cassette subfamily C member 8. (1624 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (898 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (985 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (334 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
GNG13G protein subunit gamma 13. (67 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (640 aa)
GCGGlucagon. (180 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
GNB4G protein subunit beta 4. (340 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (473 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNA14G protein subunit alpha 14. (355 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2312 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (521 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (767 aa)
GNB1G protein subunit beta 1. (340 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1112 aa)
GNAI1G protein subunit alpha i1. (354 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
GNB5G protein subunit beta 5. (386 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2193 aa)
GNB3G protein subunit beta 3. (340 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (77 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
GNAI2G protein subunit alpha i2. (355 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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